Motif ID: Hlf

Z-value: 0.631


Transcription factors associated with Hlf:

Gene SymbolEntrez IDGene Name
Hlf ENSMUSG00000003949.10 Hlf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hlfmm10_v2_chr11_-_90390895_903909260.535.8e-03Click!


Activity profile for motif Hlf.

activity profile for motif Hlf


Sorted Z-values histogram for motif Hlf

Sorted Z-values for motif Hlf



Network of associatons between targets according to the STRING database.



First level regulatory network of Hlf

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_65971049 2.129 ENSMUST00000128539.1
Clu
clusterin
chr14_+_65970804 1.993 ENSMUST00000138191.1
Clu
clusterin
chr15_-_88978958 1.953 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr14_+_65971164 1.849 ENSMUST00000144619.1
Clu
clusterin
chr4_-_151044564 1.432 ENSMUST00000103204.4
Per3
period circadian clock 3
chr17_-_31637135 1.257 ENSMUST00000118504.1
ENSMUST00000078509.5
ENSMUST00000067801.6
Cbs


cystathionine beta-synthase


chr3_+_127553462 1.212 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr19_-_50678642 1.170 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr11_-_101785252 1.043 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr18_-_80713062 1.041 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr9_-_107668967 0.976 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr5_-_3473178 0.973 ENSMUST00000168422.1
Gm17590
predicted gene, 17590
chr5_+_3343893 0.972 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr3_-_80913528 0.946 ENSMUST00000107743.1
ENSMUST00000029654.8
Glrb

glycine receptor, beta subunit

chr2_+_30834972 0.929 ENSMUST00000113592.2
Prrx2
paired related homeobox 2
chr7_+_110773658 0.903 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr6_+_90465287 0.874 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chr15_+_25758755 0.868 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr2_-_129371131 0.844 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr7_-_114636299 0.804 ENSMUST00000032906.4
ENSMUST00000032907.7
Calca

calcitonin/calcitonin-related polypeptide, alpha

chr16_+_43510267 0.787 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr11_-_77894096 0.719 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr3_+_86070915 0.693 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr3_+_66219909 0.673 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr15_-_50889691 0.662 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr7_+_110774240 0.651 ENSMUST00000147587.1
Ampd3
adenosine monophosphate deaminase 3
chr1_+_10993452 0.642 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr18_+_50030977 0.629 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr2_+_25180737 0.625 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr3_+_51559973 0.600 ENSMUST00000180404.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr3_+_40800054 0.588 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chrX_+_166238901 0.572 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr6_+_83034173 0.565 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr5_-_5514730 0.545 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr2_+_109280738 0.541 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr1_+_156838915 0.497 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr5_-_5514873 0.480 ENSMUST00000060947.7
Cldn12
claudin 12
chr19_-_28963863 0.464 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr2_-_120609500 0.453 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr7_+_27447978 0.452 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr5_-_124032214 0.451 ENSMUST00000040967.7
Vps37b
vacuolar protein sorting 37B (yeast)
chr4_-_98817537 0.433 ENSMUST00000102790.3
Kank4
KN motif and ankyrin repeat domains 4
chr3_-_88762244 0.433 ENSMUST00000183267.1
Syt11
synaptotagmin XI
chr2_-_120609283 0.431 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr10_+_20347788 0.419 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr2_-_120609319 0.418 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr4_+_111720187 0.409 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr18_-_35498856 0.408 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr4_-_97584605 0.403 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_-_109280718 0.395 ENSMUST00000147770.1
Mettl15
methyltransferase like 15
chr10_+_94576254 0.383 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr9_+_38719024 0.381 ENSMUST00000129598.1
Vwa5a
von Willebrand factor A domain containing 5A
chr4_-_97584612 0.380 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr13_+_93771656 0.371 ENSMUST00000091403.4
Arsb
arylsulfatase B
chrX_-_36864238 0.370 ENSMUST00000115249.3
ENSMUST00000115248.3
C330007P06Rik

RIKEN cDNA C330007P06 gene

chrX_-_155216338 0.364 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr3_+_40800013 0.363 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr3_+_97158767 0.362 ENSMUST00000090759.4
Acp6
acid phosphatase 6, lysophosphatidic
chrX_-_155216444 0.342 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr11_-_101551837 0.341 ENSMUST00000017290.4
Brca1
breast cancer 1
chr1_-_69685937 0.338 ENSMUST00000027146.2
Ikzf2
IKAROS family zinc finger 2
chr15_+_99393610 0.329 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr11_-_88718223 0.325 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr11_+_69045640 0.325 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr10_-_31445921 0.323 ENSMUST00000000305.5
Tpd52l1
tumor protein D52-like 1
chr15_+_99393574 0.323 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr2_+_120609383 0.320 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr17_+_47737030 0.316 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr17_+_79614900 0.309 ENSMUST00000040368.2
Rmdn2
regulator of microtubule dynamics 2
chr11_-_106216318 0.296 ENSMUST00000002043.3
Ccdc47
coiled-coil domain containing 47
chr10_+_121739915 0.296 ENSMUST00000065600.7
ENSMUST00000136432.1
BC048403

cDNA sequence BC048403

chr14_+_78849171 0.295 ENSMUST00000040990.5
Vwa8
von Willebrand factor A domain containing 8
chr9_-_123717576 0.295 ENSMUST00000026274.7
Lztfl1
leucine zipper transcription factor-like 1
chr6_+_17463749 0.294 ENSMUST00000115443.1
Met
met proto-oncogene
chr1_-_91459254 0.293 ENSMUST00000069620.8
Per2
period circadian clock 2
chr7_+_90442729 0.286 ENSMUST00000061767.4
ENSMUST00000107206.1
Crebzf

CREB/ATF bZIP transcription factor

chr12_+_117843489 0.282 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr4_-_89311021 0.270 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr15_+_99074968 0.268 ENSMUST00000039665.6
Troap
trophinin associated protein
chr19_+_34290653 0.258 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr3_+_84952146 0.258 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr15_-_98728120 0.255 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr17_+_36958571 0.250 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr11_+_110968016 0.245 ENSMUST00000106636.1
ENSMUST00000180023.1
Kcnj16

potassium inwardly-rectifying channel, subfamily J, member 16

chr13_-_106847267 0.244 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr4_+_47208005 0.236 ENSMUST00000082303.6
ENSMUST00000102917.4
Col15a1

collagen, type XV, alpha 1

chrX_-_56598069 0.236 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr14_+_26122609 0.236 ENSMUST00000100810.6
Duxbl2
doubl homeobox B-like 2
chr17_+_36958623 0.231 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr1_-_58586191 0.228 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr14_+_50944499 0.225 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr10_-_17947997 0.225 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr3_+_96104498 0.220 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
Otud7b



OTU domain containing 7B



chr12_+_73286868 0.217 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr12_+_116281180 0.217 ENSMUST00000100986.2
Esyt2
extended synaptotagmin-like protein 2
chr2_+_118861954 0.213 ENSMUST00000028807.5
Ivd
isovaleryl coenzyme A dehydrogenase
chr14_+_50955992 0.211 ENSMUST00000095925.4
Pnp2
purine-nucleoside phosphorylase 2
chr16_-_59555752 0.210 ENSMUST00000179383.1
ENSMUST00000044604.8
Crybg3

beta-gamma crystallin domain containing 3

chr11_+_110997487 0.210 ENSMUST00000106635.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr12_+_105563123 0.203 ENSMUST00000001652.5
Bdkrb2
bradykinin receptor, beta 2
chr10_+_100488289 0.203 ENSMUST00000164751.1
Cep290
centrosomal protein 290
chr13_-_100650981 0.202 ENSMUST00000022136.6
ENSMUST00000177848.1
Rad17

RAD17 homolog (S. pombe)

chr16_-_87432597 0.201 ENSMUST00000039449.7
Ltn1
listerin E3 ubiquitin protein ligase 1
chr2_-_20943413 0.198 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr3_-_127553233 0.193 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr4_+_42735545 0.188 ENSMUST00000068158.3
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr7_+_67647405 0.188 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr17_+_70561739 0.186 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr5_+_66968961 0.182 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chrX_-_21061981 0.182 ENSMUST00000040628.5
ENSMUST00000115333.2
ENSMUST00000115334.1
Zfp182


zinc finger protein 182


chr2_+_132847719 0.176 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr6_+_124808885 0.175 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr1_+_180641330 0.170 ENSMUST00000085804.5
Lin9
lin-9 homolog (C. elegans)
chr9_-_100506844 0.168 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chrX_-_12673540 0.163 ENSMUST00000060108.6
1810030O07Rik
RIKEN cDNA 1810030O07 gene
chr15_+_34238026 0.162 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr2_+_116900152 0.160 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr13_+_114818232 0.158 ENSMUST00000166104.2
ENSMUST00000166176.2
ENSMUST00000184335.1
ENSMUST00000184245.1
ENSMUST00000015680.4
ENSMUST00000184214.1
ENSMUST00000165022.2
ENSMUST00000164737.1
ENSMUST00000184781.1
ENSMUST00000183407.1
ENSMUST00000184672.1
Mocs2










molybdenum cofactor synthesis 2










chr2_+_126707319 0.154 ENSMUST00000028841.7
ENSMUST00000110416.2
Usp8

ubiquitin specific peptidase 8

chr16_-_4789887 0.150 ENSMUST00000117713.1
Cdip1
cell death inducing Trp53 target 1
chr10_-_99759658 0.145 ENSMUST00000056085.4
Csl
citrate synthase like
chr16_+_19760195 0.136 ENSMUST00000121344.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr10_+_81137953 0.132 ENSMUST00000117956.1
Zbtb7a
zinc finger and BTB domain containing 7a
chr16_-_4789984 0.130 ENSMUST00000004173.5
Cdip1
cell death inducing Trp53 target 1
chr16_-_3907651 0.130 ENSMUST00000177221.1
ENSMUST00000177323.1
1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr8_+_105636509 0.121 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr5_-_150665560 0.119 ENSMUST00000118316.1
N4bp2l2
NEDD4 binding protein 2-like 2
chr7_-_44496406 0.117 ENSMUST00000118515.1
ENSMUST00000138328.1
ENSMUST00000008284.8
ENSMUST00000118808.1
Emc10



ER membrane protein complex subunit 10



chr2_+_104027721 0.117 ENSMUST00000028603.3
Fbxo3
F-box protein 3
chr8_-_84840627 0.114 ENSMUST00000003911.6
ENSMUST00000109761.2
ENSMUST00000128035.1
Rad23a


RAD23a homolog (S. cerevisiae)


chr16_+_20097554 0.112 ENSMUST00000023509.3
Klhl24
kelch-like 24
chrX_+_75095854 0.111 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chr19_-_53371766 0.109 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr11_+_3330781 0.108 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr11_+_83662579 0.106 ENSMUST00000019074.3
Ccl4
chemokine (C-C motif) ligand 4
chr10_-_111997204 0.103 ENSMUST00000074805.5
Glipr1
GLI pathogenesis-related 1 (glioma)
chr11_+_93996082 0.103 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr11_+_80300866 0.102 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr1_+_109993982 0.101 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr11_+_110968056 0.101 ENSMUST00000125692.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_+_123477859 0.101 ENSMUST00000001520.7
Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr16_-_57606816 0.101 ENSMUST00000114371.3
Cmss1
cms small ribosomal subunit 1
chr13_+_51100810 0.096 ENSMUST00000095797.5
Spin1
spindlin 1
chr2_+_69670100 0.095 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr16_-_4790220 0.094 ENSMUST00000118703.1
Cdip1
cell death inducing Trp53 target 1
chr18_-_36726730 0.093 ENSMUST00000061829.6
Cd14
CD14 antigen
chr10_-_121626316 0.091 ENSMUST00000039810.7
Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr2_+_181497165 0.091 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
Tpd52l2




tumor protein D52-like 2




chr12_-_27342696 0.086 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chrX_-_7319291 0.085 ENSMUST00000128319.1
Clcn5
chloride channel 5
chr12_-_104865076 0.085 ENSMUST00000109937.1
ENSMUST00000109936.1
Clmn

calmin

chr7_+_132931142 0.081 ENSMUST00000106157.1
Zranb1
zinc finger, RAN-binding domain containing 1
chr5_-_147894804 0.075 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr12_+_73286779 0.074 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr7_-_35056467 0.073 ENSMUST00000130491.1
Cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr11_-_87826023 0.072 ENSMUST00000103177.3
Lpo
lactoperoxidase
chr7_-_138846202 0.070 ENSMUST00000118810.1
ENSMUST00000075667.4
ENSMUST00000119664.1
Mapk1ip1


mitogen-activated protein kinase 1 interacting protein 1


chr1_-_38129618 0.069 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr5_+_8046077 0.068 ENSMUST00000088786.4
Sri
sorcin
chr2_-_130642770 0.068 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr2_+_76650264 0.068 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr15_-_38078842 0.068 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr11_+_3330401 0.067 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr6_-_83033422 0.065 ENSMUST00000089651.5
Dok1
docking protein 1
chr8_+_117157972 0.065 ENSMUST00000064488.4
ENSMUST00000162997.1
Gan

giant axonal neuropathy

chr16_+_91391721 0.064 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr2_+_104027823 0.063 ENSMUST00000111135.1
ENSMUST00000111136.1
ENSMUST00000102565.3
Fbxo3


F-box protein 3


chr3_+_30792876 0.063 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr4_+_147868830 0.063 ENSMUST00000094481.1
Fv1
Friend virus susceptibility 1
chr7_+_110018301 0.062 ENSMUST00000084731.3
Ipo7
importin 7
chr16_-_16527364 0.061 ENSMUST00000069284.7
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr10_+_88731056 0.059 ENSMUST00000116234.2
Arl1
ADP-ribosylation factor-like 1
chr2_+_172393794 0.058 ENSMUST00000099061.2
ENSMUST00000103073.2
Cass4

Cas scaffolding protein family member 4

chr11_-_116086929 0.056 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr12_+_98771018 0.056 ENSMUST00000021399.7
Zc3h14
zinc finger CCCH type containing 14
chr12_-_110978981 0.055 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
Ankrd9


ankyrin repeat domain 9


chr7_-_133782721 0.055 ENSMUST00000063669.1
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr9_-_71163224 0.052 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr9_-_114933811 0.051 ENSMUST00000084853.3
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr10_-_22149270 0.049 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr4_+_146654927 0.046 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chr17_-_43543639 0.045 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr7_+_44468051 0.045 ENSMUST00000118493.1
Josd2
Josephin domain containing 2
chr3_-_62506970 0.041 ENSMUST00000029336.4
Dhx36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr2_+_112265809 0.040 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr2_+_164879358 0.039 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr11_-_69980468 0.035 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chr4_-_147868469 0.033 ENSMUST00000119975.2
Miip
migration and invasion inhibitory protein
chr19_+_43752996 0.032 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr1_-_165236892 0.032 ENSMUST00000043235.5
Tiprl
TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
chr4_-_11981265 0.031 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chr2_+_181497223 0.030 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr16_+_94370618 0.029 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr4_-_147868631 0.029 ENSMUST00000030886.8
ENSMUST00000172710.1
Miip

migration and invasion inhibitory protein

chr17_+_32036098 0.028 ENSMUST00000081339.6
Rrp1b
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr4_-_11254248 0.025 ENSMUST00000044616.3
ENSMUST00000108319.2
ENSMUST00000108318.2
Ints8


integrator complex subunit 8


chr1_-_52232296 0.025 ENSMUST00000114512.1
Gls
glutaminase
chr3_+_90062781 0.024 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chr17_+_32284772 0.023 ENSMUST00000181112.1
Gm26549
predicted gene, 26549
chr8_-_91133942 0.021 ENSMUST00000120213.1
ENSMUST00000109609.2
Aktip

thymoma viral proto-oncogene 1 interacting protein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.0 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.4 2.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.4 1.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.3 1.0 GO:0060854 patterning of lymph vessels(GO:0060854)
0.3 1.0 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.3 0.8 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.3 0.8 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.2 1.0 GO:0006867 asparagine transport(GO:0006867) glutamine transport(GO:0006868)
0.2 0.7 GO:0006553 lysine metabolic process(GO:0006553)
0.2 0.7 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 0.7 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 1.6 GO:0032264 IMP salvage(GO:0032264)
0.2 1.0 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.2 1.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.4 GO:1905154 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154)
0.1 0.7 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 1.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 0.5 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.9 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.0 0.2 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:1990481 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.9 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 0.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0071220 response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.5 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.6 GO:0007584 response to nutrient(GO:0007584)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.4 GO:0000266 mitochondrial fission(GO:0000266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 1.0 GO:0098536 deuterosome(GO:0098536)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 0.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 6.0 GO:0051787 misfolded protein binding(GO:0051787)
0.2 0.7 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 1.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.0 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.2 0.6 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.2 0.7 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.0 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.1 0.5 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.5 GO:0051010 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 2.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)