Motif ID: Hlx

Z-value: 0.246


Transcription factors associated with Hlx:

Gene SymbolEntrez IDGene Name
Hlx ENSMUSG00000039377.6 Hlx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hlxmm10_v2_chr1_-_184732616_1847326270.366.9e-02Click!


Activity profile for motif Hlx.

activity profile for motif Hlx


Sorted Z-values histogram for motif Hlx

Sorted Z-values for motif Hlx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hlx

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_45103747 0.521 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chrX_-_143933204 0.499 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chrX_-_143933089 0.495 ENSMUST00000087313.3
 Dcx
doublecortin
chr9_+_54980880 0.426 ENSMUST00000093844.3
 Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr15_-_8710734 0.383 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 0.365 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_50094277 0.333 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr5_-_62766153 0.265 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_180109192 0.218 ENSMUST00000143176.1
ENSMUST00000135056.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr6_+_7555053 0.172 ENSMUST00000090679.2
ENSMUST00000184986.1
 Tac1

tachykinin 1

chr19_-_53944621 0.131 ENSMUST00000135402.2
 Bbip1
BBSome interacting protein 1
chr3_+_32436376 0.084 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr7_-_34313531 0.067 ENSMUST00000108074.1
 4931406P16Rik
RIKEN cDNA 4931406P16 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.2 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.1 1.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0043205 fibril(GO:0043205)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.4 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)