Motif ID: Hmbox1

Z-value: 1.302


Transcription factors associated with Hmbox1:

Gene SymbolEntrez IDGene Name
Hmbox1 ENSMUSG00000021972.8 Hmbox1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmbox1mm10_v2_chr14_-_64949838_649498860.562.8e-03Click!


Activity profile for motif Hmbox1.

activity profile for motif Hmbox1


Sorted Z-values histogram for motif Hmbox1

Sorted Z-values for motif Hmbox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmbox1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 13.450 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr6_+_5390387 13.338 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chrX_+_100625737 6.125 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr13_-_3893556 4.586 ENSMUST00000099946.4
Net1
neuroepithelial cell transforming gene 1
chr3_-_100969644 4.413 ENSMUST00000076941.5
Ttf2
transcription termination factor, RNA polymerase II
chrX_+_159303266 3.789 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr10_+_22158566 3.639 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr7_-_25788635 3.193 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr10_+_39133981 3.189 ENSMUST00000019991.7
Tube1
epsilon-tubulin 1
chr1_-_163289214 3.096 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr15_+_25773985 3.075 ENSMUST00000125667.1
Myo10
myosin X
chr2_-_172043466 2.937 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chrX_+_169685191 2.847 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr13_-_74807913 2.787 ENSMUST00000065629.4
Cast
calpastatin
chrX_-_23266751 2.754 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr3_-_95217690 2.639 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr1_-_75278345 2.451 ENSMUST00000039534.4
Resp18
regulated endocrine-specific protein 18
chrX_-_111537947 2.269 ENSMUST00000132319.1
ENSMUST00000123951.1
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr3_-_95217877 2.240 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr11_+_83942062 2.230 ENSMUST00000049257.7
Ddx52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr3_-_79842662 2.224 ENSMUST00000029568.1
Tmem144
transmembrane protein 144
chr11_+_77686155 2.158 ENSMUST00000100802.4
ENSMUST00000181023.1
Nufip2

nuclear fragile X mental retardation protein interacting protein 2

chr2_-_169405435 2.145 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr11_-_64436653 2.128 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr11_-_94507337 2.109 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chrX_+_169879596 1.984 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr3_-_95217741 1.984 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr4_+_128993224 1.950 ENSMUST00000030583.6
ENSMUST00000102604.4
Ak2

adenylate kinase 2

chrX_-_111531163 1.889 ENSMUST00000128819.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr3_+_145118564 1.886 ENSMUST00000098538.2
ENSMUST00000106192.2
ENSMUST00000029920.8
ENSMUST00000098539.2
Odf2l



outer dense fiber of sperm tails 2-like



chr10_+_11609256 1.830 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr17_+_86963077 1.825 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr17_-_40935047 1.816 ENSMUST00000087114.3
Cenpq
centromere protein Q
chrX_-_12160355 1.777 ENSMUST00000043441.6
Bcor
BCL6 interacting corepressor
chr8_-_105347885 1.749 ENSMUST00000014922.4
Fhod1
formin homology 2 domain containing 1
chr1_-_97761538 1.748 ENSMUST00000171129.1
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr14_+_66635251 1.734 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
Adra1a


adrenergic receptor, alpha 1a


chrX_+_164419855 1.734 ENSMUST00000112255.1
Piga
phosphatidylinositol glycan anchor biosynthesis, class A
chr12_+_52097737 1.688 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr19_-_4928241 1.631 ENSMUST00000025851.3
Dpp3
dipeptidylpeptidase 3
chr1_+_88227005 1.570 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr1_+_15805639 1.524 ENSMUST00000027057.6
Terf1
telomeric repeat binding factor 1
chrX_-_38252398 1.493 ENSMUST00000089056.3
ENSMUST00000089054.4
ENSMUST00000066498.7
Tmem255a


transmembrane protein 255A


chr4_-_58912678 1.477 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180


expressed sequence AI314180


chr12_+_64965742 1.455 ENSMUST00000066296.7
Fam179b
family with sequence similarity 179, member B
chr1_+_156040884 1.455 ENSMUST00000060404.4
Tor1aip2
torsin A interacting protein 2
chr4_-_97584612 1.445 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr10_+_53596936 1.440 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr9_+_35423582 1.419 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr6_-_97179100 1.333 ENSMUST00000095664.3
Tmf1
TATA element modulatory factor 1
chr3_+_108653979 1.317 ENSMUST00000106613.1
Clcc1
chloride channel CLIC-like 1
chr10_-_128804353 1.310 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr3_+_108653907 1.298 ENSMUST00000106609.1
Clcc1
chloride channel CLIC-like 1
chr1_-_152386675 1.257 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr19_+_6105774 1.243 ENSMUST00000044451.3
Naaladl1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr3_-_69004565 1.229 ENSMUST00000169064.1
Ift80
intraflagellar transport 80
chr3_-_69004475 1.219 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80

intraflagellar transport 80

chr19_+_45015168 1.215 ENSMUST00000039016.6
Lzts2
leucine zipper, putative tumor suppressor 2
chr3_+_108653931 1.202 ENSMUST00000029483.8
ENSMUST00000124384.1
Clcc1

chloride channel CLIC-like 1

chr10_-_49783259 1.198 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr9_-_78368167 1.197 ENSMUST00000071991.5
Dppa5a
developmental pluripotency associated 5A
chr2_-_25224653 1.164 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr3_+_5218589 1.154 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr7_-_45061651 1.059 ENSMUST00000007981.3
ENSMUST00000107831.1
Prrg2

proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

chr8_-_66486494 1.059 ENSMUST00000026681.5
Tma16
translation machinery associated 16 homolog (S. cerevisiae)
chr19_+_23675839 1.054 ENSMUST00000056396.5
Gm6563
predicted pseudogene 6563
chr8_-_88362154 1.023 ENSMUST00000034085.7
Brd7
bromodomain containing 7
chr10_+_127677064 1.012 ENSMUST00000118612.1
ENSMUST00000048099.4
Tmem194

transmembrane protein 194

chr3_-_69004503 1.003 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr1_-_31222604 1.000 ENSMUST00000127775.1
4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr7_-_45061706 0.938 ENSMUST00000107832.1
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr16_+_35983424 0.918 ENSMUST00000173555.1
Kpna1
karyopherin (importin) alpha 1
chr8_+_45507768 0.905 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr13_+_55209776 0.892 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr8_+_45658666 0.883 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr13_+_49504774 0.877 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr13_-_21531084 0.870 ENSMUST00000045228.5
Zkscan8
zinc finger with KRAB and SCAN domains 8
chr2_-_128687354 0.860 ENSMUST00000110332.1
ENSMUST00000110333.1
ENSMUST00000014499.3
Anapc1


anaphase promoting complex subunit 1


chr19_+_45015198 0.855 ENSMUST00000179108.1
Lzts2
leucine zipper, putative tumor suppressor 2
chr10_-_7663569 0.830 ENSMUST00000162606.1
Pcmt1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
chr8_+_45658731 0.824 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr1_+_156040909 0.823 ENSMUST00000065648.8
ENSMUST00000097526.2
Tor1aip2

torsin A interacting protein 2

chr12_-_113361232 0.808 ENSMUST00000103423.1
Ighg3
Immunoglobulin heavy constant gamma 3
chr2_+_117249725 0.726 ENSMUST00000028825.4
Fam98b
family with sequence similarity 98, member B
chr18_-_61211572 0.674 ENSMUST00000146409.1
Slc26a2
solute carrier family 26 (sulfate transporter), member 2
chr7_+_120917744 0.665 ENSMUST00000033173.7
ENSMUST00000106483.2
Polr3e

polymerase (RNA) III (DNA directed) polypeptide E

chr1_-_137969213 0.662 ENSMUST00000182680.1
ENSMUST00000182424.1
Gm26936

predicted gene, 26936

chr6_+_29853746 0.642 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr8_+_9977707 0.641 ENSMUST00000139793.1
ENSMUST00000048216.5
Abhd13

abhydrolase domain containing 13

chr10_-_40257648 0.637 ENSMUST00000019982.7
Gtf3c6
general transcription factor IIIC, polypeptide 6, alpha
chr13_-_90905321 0.628 ENSMUST00000109541.3
Atp6ap1l
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr8_+_11556061 0.606 ENSMUST00000054399.4
Ing1
inhibitor of growth family, member 1
chr11_+_101468164 0.603 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr7_+_83891983 0.562 ENSMUST00000094215.3
ENSMUST00000130103.1
Mesdc2

mesoderm development candidate 2

chr12_-_64965496 0.537 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr12_-_31634592 0.525 ENSMUST00000020979.7
ENSMUST00000177962.1
Bcap29

B cell receptor associated protein 29

chr18_-_6241470 0.516 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr11_-_4704334 0.481 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr4_+_116558056 0.476 ENSMUST00000106475.1
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr4_+_20042046 0.465 ENSMUST00000098242.3
Ggh
gamma-glutamyl hydrolase
chr4_+_100478806 0.454 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chrM_+_5319 0.445 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr3_+_95588928 0.438 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr18_+_65698253 0.421 ENSMUST00000115097.1
ENSMUST00000117694.1
Oacyl

O-acyltransferase like

chr8_-_107588392 0.417 ENSMUST00000044106.4
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr18_-_6241486 0.385 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr14_-_63193541 0.375 ENSMUST00000038229.4
Neil2
nei like 2 (E. coli)
chr10_-_128525859 0.370 ENSMUST00000026427.6
Esyt1
extended synaptotagmin-like protein 1
chr1_+_59256906 0.357 ENSMUST00000160662.1
ENSMUST00000114248.2
Cdk15

cyclin-dependent kinase 15

chr17_+_56079652 0.346 ENSMUST00000002911.8
Hdgfrp2
hepatoma-derived growth factor, related protein 2
chr1_-_191907527 0.338 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr19_+_8757139 0.336 ENSMUST00000183939.1
Nxf1
nuclear RNA export factor 1
chr5_-_48754521 0.318 ENSMUST00000101214.2
ENSMUST00000176191.1
Kcnip4

Kv channel interacting protein 4

chr7_+_116093296 0.292 ENSMUST00000032899.5
1110004F10Rik
RIKEN cDNA 1110004F10 gene
chr3_+_95588960 0.263 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chrX_+_135993820 0.227 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr4_-_119174178 0.216 ENSMUST00000106355.3
Zfp691
zinc finger protein 691
chr5_-_136565432 0.209 ENSMUST00000176172.1
Cux1
cut-like homeobox 1
chr12_+_17266545 0.199 ENSMUST00000057288.5
Pdia6
protein disulfide isomerase associated 6
chr11_+_93996082 0.196 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr3_+_95588990 0.195 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr15_+_55112317 0.186 ENSMUST00000096433.3
Deptor
DEP domain containing MTOR-interacting protein
chr19_+_8757099 0.181 ENSMUST00000184970.1
Nxf1
nuclear RNA export factor 1
chr4_+_117252010 0.170 ENSMUST00000125943.1
ENSMUST00000106434.1
Tmem53

transmembrane protein 53

chr4_-_40757823 0.169 ENSMUST00000030117.4
Smu1
smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
chr12_-_81532840 0.168 ENSMUST00000166664.1
ENSMUST00000164386.1
ENSMUST00000169158.1
ENSMUST00000164431.1
ENSMUST00000163402.1
Gm20498

Synj2bp


predicted gene 20498

synaptojanin 2 binding protein


chr2_-_157571270 0.164 ENSMUST00000173378.1
Blcap
bladder cancer associated protein homolog (human)
chr8_-_9977650 0.156 ENSMUST00000170033.1
Lig4
ligase IV, DNA, ATP-dependent
chr12_+_69963452 0.154 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr7_+_140881898 0.151 ENSMUST00000026560.7
Psmd13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr10_-_11080956 0.142 ENSMUST00000105560.1
Grm1
glutamate receptor, metabotropic 1
chr10_-_81600857 0.140 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
Tle6


transducin-like enhancer of split 6, homolog of Drosophila E(spl)


chr17_+_40934676 0.134 ENSMUST00000169611.2
Mut
methylmalonyl-Coenzyme A mutase
chr14_-_70323783 0.090 ENSMUST00000151011.1
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr14_-_55671873 0.075 ENSMUST00000163750.1
ENSMUST00000010520.8
Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr19_+_5038826 0.049 ENSMUST00000053705.6
B3gnt1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr15_-_79285502 0.047 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr3_-_116711820 0.043 ENSMUST00000153108.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr1_-_170589791 0.025 ENSMUST00000161966.1
ENSMUST00000160456.1
Nos1ap

nitric oxide synthase 1 (neuronal) adaptor protein

chr1_-_152386589 0.014 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 13.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.3 13.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.9 6.1 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.8 3.2 GO:2000668 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.6 1.7 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.5 1.5 GO:0031627 telomeric loop formation(GO:0031627)
0.4 1.3 GO:2000834 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.4 1.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.4 2.8 GO:0007343 egg activation(GO:0007343)
0.4 3.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.3 4.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.3 1.9 GO:0006172 ADP biosynthetic process(GO:0006172)
0.3 0.9 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.3 4.6 GO:0051451 myoblast migration(GO:0051451)
0.3 3.1 GO:0048664 neuron fate determination(GO:0048664)
0.2 4.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.2 0.9 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 0.7 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.2 2.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.2 1.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 0.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 3.6 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 4.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 1.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.8 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 1.6 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 2.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.8 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.0 3.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 2.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-dependent nucleosome organization(GO:0034723) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 3.8 GO:0006821 chloride transport(GO:0006821)
0.0 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.0 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 3.1 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)
0.0 2.1 GO:0000910 cytokinesis(GO:0000910)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.2 3.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.5 2.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 1.9 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.2 1.5 GO:0070187 telosome(GO:0070187)
0.2 1.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 2.2 GO:0042788 polysomal ribosome(GO:0042788)
0.2 3.2 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 1.2 GO:0045298 tubulin complex(GO:0045298)
0.1 1.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 7.0 GO:0005871 kinesin complex(GO:0005871)
0.1 2.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 3.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.1 1.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 3.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 5.3 GO:0005874 microtubule(GO:0005874)
0.0 2.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.0 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 4.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.8 GO:0005884 actin filament(GO:0005884)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.8 GO:0000775 chromosome, centromeric region(GO:0000775)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.5 7.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.5 3.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.4 1.7 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 3.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 0.9 GO:0070052 collagen V binding(GO:0070052)
0.3 1.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 4.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 1.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.2 0.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 6.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.2 GO:0016805 dipeptidase activity(GO:0016805)
0.1 2.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 4.5 GO:0005254 chloride channel activity(GO:0005254)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 11.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.1 GO:0030507 spectrin binding(GO:0030507)
0.1 1.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 12.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 5.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.0 0.4 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 4.8 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 4.0 GO:0000287 magnesium ion binding(GO:0000287)