Motif ID: Hmga1

Z-value: 0.832


Transcription factors associated with Hmga1:

Gene SymbolEntrez IDGene Name
Hmga1 ENSMUSG00000046711.9 Hmga1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga1mm10_v2_chr17_+_27556613_27556635-0.154.8e-01Click!


Activity profile for motif Hmga1.

activity profile for motif Hmga1


Sorted Z-values histogram for motif Hmga1

Sorted Z-values for motif Hmga1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_45981548 3.149 ENSMUST00000085632.2
 Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr13_-_85127514 3.104 ENSMUST00000179230.1
 Gm4076
predicted gene 4076
chr4_+_105789869 2.481 ENSMUST00000184254.1
 Gm12728
predicted gene 12728
chr10_+_96136603 2.192 ENSMUST00000074615.6
 Gm5426
predicted pseudogene 5426
chrX_-_103483205 2.189 ENSMUST00000127786.2
 Xist
inactive X specific transcripts
chr3_-_88577208 1.905 ENSMUST00000098952.2
 Gm10704
predicted pseudogene 10704
chr15_+_99006056 1.861 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr15_+_31276491 1.449 ENSMUST00000068987.5
 Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chr13_-_41273977 1.359 ENSMUST00000163881.1
 Gm17364
predicted gene, 17364
chr10_+_4611971 1.150 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr18_+_35770318 0.810 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chr16_-_36784924 0.770 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
 Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chrX_+_166344692 0.704 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr3_-_121171678 0.690 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
 Rwdd3




RWD domain containing 3




chr17_+_85620816 0.670 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr17_+_3397189 0.661 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr7_+_34251038 0.660 ENSMUST00000105172.1
 Gm6096
predicted gene 6096
chr1_+_180101144 0.647 ENSMUST00000133890.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr5_+_17574726 0.638 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chrX_-_93632113 0.575 ENSMUST00000006856.2
 Pola1
polymerase (DNA directed), alpha 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 1.8 GO:0007097 nuclear migration(GO:0007097)
0.0 1.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.2 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.2 0.8 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.8 GO:0014037 Schwann cell differentiation(GO:0014037)
0.2 0.7 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2 0.7 GO:0097402 neuroblast migration(GO:0097402)
0.1 0.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.6 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.6 GO:0006273 lagging strand elongation(GO:0006273)
0.2 0.5 GO:0060423 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) negative regulation of mitotic cell cycle, embryonic(GO:0045976) foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:0000805 X chromosome(GO:0000805)
0.1 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.8 GO:0031262 Ndc80 complex(GO:0031262)
0.2 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.5 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.4 1.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 0.8 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.6 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.6 GO:0043495 protein anchor(GO:0043495)
0.2 0.5 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.5 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)