Motif ID: Hmga2

Z-value: 1.057


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_120476527-0.262.0e-01Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

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Top targets:


Showing 1 to 20 of 129 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_19418930 4.346 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3013140 4.295 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr2_-_98667264 3.989 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr9_+_3004457 3.683 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr11_+_22971991 3.629 ENSMUST00000049506.5
 Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr9_+_3025417 3.028 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3023547 2.823 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3018753 2.811 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr9_+_3017408 2.505 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr10_+_123264076 2.424 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr7_-_5413145 1.899 ENSMUST00000108569.2
 Vmn1r58
vomeronasal 1 receptor 58
chr10_-_117282262 1.825 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr4_+_130913120 1.655 ENSMUST00000151698.1
 Laptm5
lysosomal-associated protein transmembrane 5
chr11_-_102897123 1.612 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr16_-_43979050 1.500 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr16_-_26371828 1.364 ENSMUST00000023154.2
 Cldn1
claudin 1
chr3_+_53845086 1.359 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr11_+_82035569 1.270 ENSMUST00000000193.5
 Ccl2
chemokine (C-C motif) ligand 2
chr9_-_123260776 1.238 ENSMUST00000068140.4
 Tmem158
transmembrane protein 158
chr4_+_44756553 1.214 ENSMUST00000107824.2
 Zcchc7
zinc finger, CCHC domain containing 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.4 2.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.1 2.4 GO:0019835 cytolysis(GO:0019835)
0.1 1.5 GO:0018345 protein palmitoylation(GO:0018345)
0.2 1.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 1.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 1.2 GO:0045214 sarcomere organization(GO:0045214)
0.2 1.1 GO:0032929 negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929)
0.0 1.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 0.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.8 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.7 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.2 0.6 GO:0070269 pyroptosis(GO:0070269)
0.1 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 0.5 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.6 GO:0089701 U2AF(GO:0089701)
0.7 2.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 1.3 GO:0044299 C-fiber(GO:0044299)
0.1 1.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.9 GO:0070688 MLL5-L complex(GO:0070688)
0.2 0.8 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 0.6 GO:0061702 inflammasome complex(GO:0061702)
0.2 0.5 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.3 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.2 GO:0005940 septin ring(GO:0005940)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.3 1.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)