Motif ID: Hmx2
Z-value: 0.478
Transcription factors associated with Hmx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hmx2 | ENSMUSG00000050100.7 | Hmx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hmx2 | mm10_v2_chr7_+_131548755_131548773 | 0.69 | 1.0e-04 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0060769 | positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339) |
0.6 | 2.4 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.5 | 1.6 | GO:0035799 | ureter maturation(GO:0035799) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) |
0.3 | 0.8 | GO:0090274 | positive regulation of somatostatin secretion(GO:0090274) |
0.3 | 0.8 | GO:0046544 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544) |
0.2 | 0.6 | GO:0070269 | pyroptosis(GO:0070269) |
0.1 | 0.4 | GO:0048014 | Tie signaling pathway(GO:0048014) |
0.1 | 0.5 | GO:0032512 | regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.1 | 0.5 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
0.1 | 0.4 | GO:0015889 | cobalamin transport(GO:0015889) |
0.1 | 0.3 | GO:0045472 | response to ether(GO:0045472) |
0.1 | 0.4 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 0.5 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
0.1 | 0.3 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
0.1 | 0.6 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
0.1 | 0.4 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.1 | 1.0 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.1 | 0.4 | GO:0070814 | hydrogen sulfide biosynthetic process(GO:0070814) |
0.0 | 0.3 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
0.0 | 0.3 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
0.0 | 0.2 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.0 | 0.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.0 | 1.1 | GO:0021854 | hypothalamus development(GO:0021854) |
0.0 | 0.9 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.0 | 0.4 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
0.0 | 0.7 | GO:0045589 | regulation of regulatory T cell differentiation(GO:0045589) |
0.0 | 0.3 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 0.2 | GO:0098734 | protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734) |
0.0 | 0.1 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.0 | 0.2 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503) |
0.0 | 0.3 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
0.0 | 0.1 | GO:0072592 | regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
0.0 | 0.2 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.0 | 1.0 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
0.0 | 0.3 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.4 | GO:0003351 | epithelial cilium movement(GO:0003351) |
0.0 | 0.1 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.0 | 1.0 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 0.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.6 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 0.4 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.1 | GO:0046085 | adenosine metabolic process(GO:0046085) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.6 | GO:0061702 | inflammasome complex(GO:0061702) |
0.1 | 0.3 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.1 | 0.3 | GO:0036156 | inner dynein arm(GO:0036156) |
0.1 | 0.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 0.3 | GO:0042585 | germinal vesicle(GO:0042585) |
0.1 | 0.5 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.1 | 0.7 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.0 | 0.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 0.3 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.0 | 0.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.0 | 0.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.0 | 0.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 0.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 0.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.0 | 0.1 | GO:0071438 | NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438) |
0.0 | 1.0 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.3 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 0.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.1 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.4 | GO:0043034 | costamere(GO:0043034) |
0.0 | 1.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.8 | GO:0005113 | patched binding(GO:0005113) |
0.3 | 1.6 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.2 | 0.5 | GO:0071862 | protein phosphatase type 1 activator activity(GO:0071862) |
0.1 | 0.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 0.3 | GO:0008142 | oxysterol binding(GO:0008142) |
0.1 | 0.6 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.1 | 0.5 | GO:0043495 | protein anchor(GO:0043495) |
0.1 | 0.3 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
0.1 | 0.4 | GO:0031419 | cobalamin binding(GO:0031419) |
0.0 | 0.3 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.5 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
0.0 | 0.3 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.0 | 0.1 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.3 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) |
0.0 | 0.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.1 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.0 | 0.2 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.0 | 0.3 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.0 | 1.0 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 0.8 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.3 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.3 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.0 | 0.6 | GO:0003690 | double-stranded DNA binding(GO:0003690) |
0.0 | 0.4 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.1 | GO:0042806 | fucose binding(GO:0042806) |
0.0 | 0.2 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.0 | 0.8 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
0.0 | 0.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 1.6 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.2 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 3.8 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.1 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.0 | 0.5 | GO:0004559 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
0.0 | 0.2 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.4 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |