Motif ID: Hmx3

Z-value: 0.357


Transcription factors associated with Hmx3:

Gene SymbolEntrez IDGene Name
Hmx3 ENSMUSG00000040148.5 Hmx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx3mm10_v2_chr7_+_131542867_1315428670.106.3e-01Click!


Activity profile for motif Hmx3.

activity profile for motif Hmx3


Sorted Z-values histogram for motif Hmx3

Sorted Z-values for motif Hmx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_83487708 0.815 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr1_-_175979114 0.709 ENSMUST00000104983.1
 B020018G12Rik
RIKEN cDNA B020018G12 gene
chr10_+_106470281 0.676 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr11_+_103133303 0.626 ENSMUST00000107037.1
 Hexim2
hexamethylene bis-acetamide inducible 2
chr4_-_45532470 0.626 ENSMUST00000147448.1
 Shb
src homology 2 domain-containing transforming protein B
chr4_+_144893127 0.600 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_78968079 0.490 ENSMUST00000049117.5
 Gm5830
predicted pseudogene 5830
chr11_+_103133333 0.481 ENSMUST00000124928.1
ENSMUST00000062530.4
 Hexim2

hexamethylene bis-acetamide inducible 2

chr14_-_55560340 0.404 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr14_+_54464141 0.400 ENSMUST00000022782.8
 Lrp10
low-density lipoprotein receptor-related protein 10
chr19_+_41933464 0.391 ENSMUST00000026154.7
 Zdhhc16
zinc finger, DHHC domain containing 16
chr7_+_3645267 0.378 ENSMUST00000038913.9
 Cnot3
CCR4-NOT transcription complex, subunit 3
chr2_-_45112890 0.376 ENSMUST00000076836.6
 Zeb2
zinc finger E-box binding homeobox 2
chr7_-_121035096 0.369 ENSMUST00000065740.2
 Gm9905
predicted gene 9905
chr7_-_30559600 0.368 ENSMUST00000043975.4
ENSMUST00000156241.1
 Lin37

lin-37 homolog (C. elegans)

chrX_+_159708593 0.351 ENSMUST00000080394.6
 Sh3kbp1
SH3-domain kinase binding protein 1
chr4_+_65604984 0.309 ENSMUST00000050850.7
ENSMUST00000107366.1
 Trim32

tripartite motif-containing 32

chr7_-_126897424 0.304 ENSMUST00000120007.1
 Tmem219
transmembrane protein 219
chr13_+_118714678 0.300 ENSMUST00000022246.8
 Fgf10
fibroblast growth factor 10
chr7_-_30559828 0.277 ENSMUST00000108164.1
 Lin37
lin-37 homolog (C. elegans)
chr10_+_99263224 0.274 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr1_-_158814469 0.254 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr2_-_153015331 0.253 ENSMUST00000028972.8
 Pdrg1
p53 and DNA damage regulated 1
chr7_-_127208423 0.243 ENSMUST00000120705.1
 Tbc1d10b
TBC1 domain family, member 10b
chr9_+_21955747 0.239 ENSMUST00000053583.5
 Swsap1
SWIM type zinc finger 7 associated protein 1
chr2_-_130424242 0.238 ENSMUST00000089581.4
 Pced1a
PC-esterase domain containing 1A
chr7_+_25267669 0.234 ENSMUST00000169266.1
 Cic
capicua homolog (Drosophila)
chr19_+_8802486 0.211 ENSMUST00000172175.1
 Zbtb3
zinc finger and BTB domain containing 3
chr5_-_137684665 0.209 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
 Agfg2


ArfGAP with FG repeats 2


chr3_-_86548268 0.195 ENSMUST00000077524.3
 Mab21l2
mab-21-like 2 (C. elegans)
chr3_+_109573907 0.181 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chr11_+_114668524 0.175 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
 Rpl38



ribosomal protein L38



chr11_+_69838514 0.155 ENSMUST00000133967.1
ENSMUST00000094065.4
 Tmem256

transmembrane protein 256

chr7_+_79273201 0.139 ENSMUST00000037315.6
 Abhd2
abhydrolase domain containing 2
chr19_+_11965817 0.136 ENSMUST00000025590.9
 Osbp
oxysterol binding protein
chr18_+_61639542 0.129 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr7_+_25681158 0.122 ENSMUST00000108403.3
 B9d2
B9 protein domain 2
chr17_-_57247632 0.117 ENSMUST00000005975.6
 Gpr108
G protein-coupled receptor 108
chr9_-_123678782 0.114 ENSMUST00000170591.1
ENSMUST00000171647.1
 Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr7_-_45510400 0.102 ENSMUST00000033096.7
 Nucb1
nucleobindin 1
chrM_+_9452 0.093 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr19_-_41933276 0.085 ENSMUST00000075280.4
ENSMUST00000112123.2
 Exosc1

exosome component 1

chr9_-_123678873 0.076 ENSMUST00000040960.6
 Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr12_-_108179237 0.061 ENSMUST00000071095.7
 Setd3
SET domain containing 3
chr4_+_134397380 0.059 ENSMUST00000105870.1
 Pafah2
platelet-activating factor acetylhydrolase 2
chr13_-_92131494 0.056 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr3_+_96629919 0.051 ENSMUST00000048915.6
 Rbm8a
RNA binding motif protein 8a
chr2_-_130424673 0.049 ENSMUST00000110277.1
 Pced1a
PC-esterase domain containing 1A
chr5_-_87482258 0.047 ENSMUST00000079811.6
ENSMUST00000144144.1
 Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr2_+_3114220 0.044 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr5_+_121777929 0.043 ENSMUST00000160821.1
 Atxn2
ataxin 2
chr3_+_62419668 0.039 ENSMUST00000161057.1
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr5_+_15516489 0.014 ENSMUST00000178227.1
 Gm21847
predicted gene, 21847
chr4_-_129261394 0.010 ENSMUST00000145261.1
 C77080
expressed sequence C77080

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:1903265 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0036233 glycine import(GO:0036233)
0.0 1.1 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)