Motif ID: Hmx3

Z-value: 0.357


Transcription factors associated with Hmx3:

Gene SymbolEntrez IDGene Name
Hmx3 ENSMUSG00000040148.5 Hmx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx3mm10_v2_chr7_+_131542867_1315428670.106.3e-01Click!


Activity profile for motif Hmx3.

activity profile for motif Hmx3


Sorted Z-values histogram for motif Hmx3

Sorted Z-values for motif Hmx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 54 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_83487708 0.815 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr1_-_175979114 0.709 ENSMUST00000104983.1
 B020018G12Rik
RIKEN cDNA B020018G12 gene
chr10_+_106470281 0.676 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr11_+_103133303 0.626 ENSMUST00000107037.1
 Hexim2
hexamethylene bis-acetamide inducible 2
chr4_-_45532470 0.626 ENSMUST00000147448.1
 Shb
src homology 2 domain-containing transforming protein B
chr4_+_144893127 0.600 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_78968079 0.490 ENSMUST00000049117.5
 Gm5830
predicted pseudogene 5830
chr11_+_103133333 0.481 ENSMUST00000124928.1
ENSMUST00000062530.4
 Hexim2

hexamethylene bis-acetamide inducible 2

chr14_-_55560340 0.404 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr14_+_54464141 0.400 ENSMUST00000022782.8
 Lrp10
low-density lipoprotein receptor-related protein 10
chr19_+_41933464 0.391 ENSMUST00000026154.7
 Zdhhc16
zinc finger, DHHC domain containing 16
chr7_+_3645267 0.378 ENSMUST00000038913.9
 Cnot3
CCR4-NOT transcription complex, subunit 3
chr2_-_45112890 0.376 ENSMUST00000076836.6
 Zeb2
zinc finger E-box binding homeobox 2
chr7_-_121035096 0.369 ENSMUST00000065740.2
 Gm9905
predicted gene 9905
chr7_-_30559600 0.368 ENSMUST00000043975.4
ENSMUST00000156241.1
 Lin37

lin-37 homolog (C. elegans)

chrX_+_159708593 0.351 ENSMUST00000080394.6
 Sh3kbp1
SH3-domain kinase binding protein 1
chr4_+_65604984 0.309 ENSMUST00000050850.7
ENSMUST00000107366.1
 Trim32

tripartite motif-containing 32

chr7_-_126897424 0.304 ENSMUST00000120007.1
 Tmem219
transmembrane protein 219
chr13_+_118714678 0.300 ENSMUST00000022246.8
 Fgf10
fibroblast growth factor 10
chr7_-_30559828 0.277 ENSMUST00000108164.1
 Lin37
lin-37 homolog (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.3 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.3 GO:1903265 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0036233 glycine import(GO:0036233)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.1 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)

Gene overrepresentation in molecular_function category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)