Motif ID: Hnf1b

Z-value: 1.105


Transcription factors associated with Hnf1b:

Gene SymbolEntrez IDGene Name
Hnf1b ENSMUSG00000020679.5 Hnf1b



Activity profile for motif Hnf1b.

activity profile for motif Hnf1b


Sorted Z-values histogram for motif Hnf1b

Sorted Z-values for motif Hnf1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf1b

PNG image of the network

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Top targets:


Showing 1 to 20 of 123 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_106464167 5.308 ENSMUST00000049507.5
 Pcsk9
proprotein convertase subtilisin/kexin type 9
chr13_-_53286052 4.929 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr9_-_106158109 4.885 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr19_+_23723279 4.716 ENSMUST00000067077.1
 Gm9938
predicted gene 9938
chr7_-_144751968 4.244 ENSMUST00000155175.1
 Ano1
anoctamin 1, calcium activated chloride channel
chr10_-_76110956 4.076 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr10_-_7212222 3.882 ENSMUST00000015346.5
 Cnksr3
Cnksr family member 3
chr17_-_71459300 3.488 ENSMUST00000183937.1
 Gm4707
predicted gene 4707
chr11_-_76027726 3.394 ENSMUST00000021207.6
 Fam101b
family with sequence similarity 101, member B
chr2_+_167777467 3.377 ENSMUST00000139927.1
ENSMUST00000127441.1
 Gm14321

predicted gene 14321

chrX_+_52791179 3.365 ENSMUST00000101588.1
 Ccdc160
coiled-coil domain containing 160
chr4_-_134767940 2.917 ENSMUST00000037828.6
 Ldlrap1
low density lipoprotein receptor adaptor protein 1
chr3_+_154597352 2.652 ENSMUST00000140644.1
ENSMUST00000144764.1
ENSMUST00000155232.1
 Cryz


crystallin, zeta


chr9_+_99629496 2.628 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
 Dzip1l


DAZ interacting protein 1-like


chr14_+_46882854 2.517 ENSMUST00000022386.8
ENSMUST00000100672.3
 Samd4

sterile alpha motif domain containing 4

chr9_+_15520830 2.370 ENSMUST00000178999.1
 Smco4
single-pass membrane protein with coiled-coil domains 4
chr1_-_4880669 2.335 ENSMUST00000078030.3
 Gm6104
predicted gene 6104
chr1_-_36273425 2.256 ENSMUST00000056946.6
 Neurl3
neuralized homolog 3 homolog (Drosophila)
chr3_-_138131356 2.252 ENSMUST00000029805.8
 Mttp
microsomal triglyceride transfer protein
chr2_+_158768083 2.203 ENSMUST00000029183.2
 Fam83d
family with sequence similarity 83, member D

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 5.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
1.0 4.9 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.8 4.2 GO:0015705 iodide transport(GO:0015705)
0.7 4.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 3.9 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.1 3.4 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.5 2.9 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 2.9 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.2 2.7 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 2.5 GO:0045727 positive regulation of translation(GO:0045727)
0.5 2.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.7 2.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 2.2 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.7 2.1 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.4 1.9 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.8 GO:0090400 stress-induced premature senescence(GO:0090400)
0.6 1.7 GO:0097274 urea homeostasis(GO:0097274)
0.3 1.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.5 1.5 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 5.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 4.8 GO:0005814 centriole(GO:0005814)
0.1 4.2 GO:0034707 chloride channel complex(GO:0034707)
0.7 2.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 2.3 GO:0031528 microvillus membrane(GO:0031528)
0.2 2.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 2.2 GO:0031143 pseudopodium(GO:0031143)
0.1 2.2 GO:0010369 chromocenter(GO:0010369)
0.1 2.1 GO:0001741 XY body(GO:0001741)
0.1 1.8 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.5 GO:0043034 costamere(GO:0043034)
0.4 1.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.4 1.3 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 1.2 GO:0033655 host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.1 1.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.0 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 GO:0070491 repressing transcription factor binding(GO:0070491)
1.8 5.3 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.2 4.9 GO:0017147 Wnt-protein binding(GO:0017147)
1.1 4.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 4.1 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.2 3.4 GO:0031005 filamin binding(GO:0031005)
0.7 2.9 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.3 2.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.7 GO:0070402 NADPH binding(GO:0070402)
0.1 2.4 GO:0030371 translation repressor activity(GO:0030371)
0.0 2.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 2.2 GO:0019894 kinesin binding(GO:0019894)
0.4 2.1 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1 1.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.8 GO:0005178 integrin binding(GO:0005178)
0.1 1.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.6 GO:0008143 poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266)
0.5 1.5 GO:0035939 microsatellite binding(GO:0035939)
0.3 1.5 GO:0015265 urea channel activity(GO:0015265)