Motif ID: Hnf1b
Z-value: 1.105
Transcription factors associated with Hnf1b:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hnf1b | ENSMUSG00000020679.5 | Hnf1b |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 5.3 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
1.1 | 3.4 | GO:1900158 | negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
1.0 | 4.9 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
0.8 | 4.2 | GO:0015705 | iodide transport(GO:0015705) |
0.7 | 2.2 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
0.7 | 2.1 | GO:1904884 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
0.7 | 4.1 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.6 | 1.7 | GO:0097274 | urea homeostasis(GO:0097274) |
0.5 | 1.5 | GO:0003195 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
0.5 | 2.9 | GO:0098700 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.5 | 2.3 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.4 | 1.9 | GO:0072757 | cellular response to camptothecin(GO:0072757) |
0.4 | 1.1 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.4 | 1.4 | GO:0050748 | negative regulation of lipoprotein metabolic process(GO:0050748) |
0.3 | 1.6 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.3 | 1.3 | GO:0015793 | glycerol transport(GO:0015793) |
0.3 | 1.1 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
0.2 | 1.4 | GO:0036112 | medium-chain fatty-acyl-CoA metabolic process(GO:0036112) |
0.2 | 2.9 | GO:0034383 | low-density lipoprotein particle clearance(GO:0034383) |
0.2 | 1.8 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.2 | 0.6 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
0.2 | 0.9 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
0.2 | 0.8 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
0.2 | 2.7 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.2 | 0.7 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
0.1 | 1.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.1 | 3.9 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
0.1 | 1.1 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.1 | 0.7 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.1 | 1.4 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
0.1 | 0.9 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.1 | 1.0 | GO:0033147 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.1 | 0.6 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.1 | 0.3 | GO:1904956 | regulation of endodermal cell fate specification(GO:0042663) motor learning(GO:0061743) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) |
0.1 | 0.6 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
0.1 | 0.4 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
0.1 | 0.4 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.1 | 0.4 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
0.1 | 0.9 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.1 | 1.5 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.1 | 0.3 | GO:0071267 | amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267) |
0.1 | 2.2 | GO:0072698 | protein localization to microtubule cytoskeleton(GO:0072698) |
0.1 | 0.3 | GO:0015791 | polyol transport(GO:0015791) urea transport(GO:0015840) urea transmembrane transport(GO:0071918) |
0.1 | 0.6 | GO:0015838 | amino-acid betaine transport(GO:0015838) |
0.1 | 1.1 | GO:0006825 | copper ion transport(GO:0006825) |
0.1 | 0.6 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.1 | 1.0 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.0 | 0.7 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 1.5 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
0.0 | 0.1 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
0.0 | 0.6 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.0 | 0.6 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.0 | 1.0 | GO:0070232 | regulation of T cell apoptotic process(GO:0070232) |
0.0 | 0.9 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.2 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.0 | 1.5 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
0.0 | 0.2 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
0.0 | 0.4 | GO:0010225 | response to UV-C(GO:0010225) |
0.0 | 1.9 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.8 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
0.0 | 0.5 | GO:0033194 | response to hydroperoxide(GO:0033194) |
0.0 | 0.6 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 1.2 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.0 | 2.5 | GO:0045727 | positive regulation of translation(GO:0045727) |
0.0 | 1.4 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
0.0 | 0.6 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 0.3 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.1 | GO:1902369 | negative regulation of RNA catabolic process(GO:1902369) |
0.0 | 0.4 | GO:0006414 | translational elongation(GO:0006414) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 5.3 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
0.7 | 2.9 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.4 | 1.3 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.4 | 1.4 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
0.3 | 0.9 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.3 | 0.9 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
0.2 | 1.0 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.2 | 0.9 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.2 | 2.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.1 | 2.3 | GO:0031528 | microvillus membrane(GO:0031528) |
0.1 | 2.2 | GO:0031143 | pseudopodium(GO:0031143) |
0.1 | 0.7 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 1.1 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.1 | 1.8 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 2.2 | GO:0010369 | chromocenter(GO:0010369) |
0.1 | 4.2 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 2.1 | GO:0001741 | XY body(GO:0001741) |
0.1 | 1.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.1 | 1.5 | GO:0016580 | Sin3 complex(GO:0016580) |
0.1 | 1.2 | GO:0033655 | host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) |
0.1 | 0.7 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
0.1 | 0.6 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 4.8 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.8 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 1.5 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.2 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
0.0 | 1.1 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.3 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.0 | 0.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.0 | 0.8 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 5.3 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
1.1 | 4.2 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
0.7 | 2.9 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
0.5 | 1.5 | GO:0035939 | microsatellite binding(GO:0035939) |
0.4 | 1.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.4 | 2.1 | GO:0032405 | MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407) |
0.3 | 1.4 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
0.3 | 2.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.3 | 1.3 | GO:0035877 | death effector domain binding(GO:0035877) |
0.3 | 4.1 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.3 | 1.5 | GO:0015265 | urea channel activity(GO:0015265) |
0.2 | 1.1 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.2 | 3.4 | GO:0031005 | filamin binding(GO:0031005) |
0.2 | 0.8 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.2 | 4.9 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.2 | 1.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
0.1 | 2.7 | GO:0070402 | NADPH binding(GO:0070402) |
0.1 | 1.0 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
0.1 | 0.7 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.1 | 0.6 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
0.1 | 1.7 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
0.1 | 1.5 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
0.1 | 1.6 | GO:0008143 | poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266) |
0.1 | 1.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 2.4 | GO:0030371 | translation repressor activity(GO:0030371) |
0.1 | 0.3 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.1 | 1.7 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 6.0 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.1 | 1.2 | GO:0005537 | mannose binding(GO:0005537) |
0.1 | 1.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 0.6 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 0.9 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.0 | 0.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 2.2 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
0.0 | 0.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 2.2 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.6 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 0.4 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 0.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.2 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
0.0 | 1.4 | GO:0016209 | antioxidant activity(GO:0016209) |
0.0 | 0.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.2 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
0.0 | 0.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.9 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 1.8 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.0 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.0 | 0.6 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.8 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |