Motif ID: Hnf4a

Z-value: 0.694


Transcription factors associated with Hnf4a:

Gene SymbolEntrez IDGene Name
Hnf4a ENSMUSG00000017950.10 Hnf4a



Activity profile for motif Hnf4a.

activity profile for motif Hnf4a


Sorted Z-values histogram for motif Hnf4a

Sorted Z-values for motif Hnf4a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf4a

PNG image of the network

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Top targets:


Showing 1 to 20 of 199 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_101840602 2.456 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr2_-_131043088 2.299 ENSMUST00000110240.3
ENSMUST00000066958.4
ENSMUST00000110235.1
 Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr2_-_131042682 2.242 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
 Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr14_+_101840501 2.217 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr9_-_77347816 2.012 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr7_+_45896941 1.900 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr11_+_104282371 1.890 ENSMUST00000106988.1
ENSMUST00000106989.1
 Mapt

microtubule-associated protein tau

chr9_-_77347787 1.631 ENSMUST00000184848.1
ENSMUST00000184415.1
 Mlip

muscular LMNA-interacting protein

chr11_-_81968415 1.581 ENSMUST00000066197.6
 Asic2
acid-sensing (proton-gated) ion channel 2
chr7_+_45897429 1.470 ENSMUST00000140243.1
 Tmem143
transmembrane protein 143
chrX_-_162565514 1.406 ENSMUST00000154424.1
 Reps2
RALBP1 associated Eps domain containing protein 2
chr7_+_112225856 1.347 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
 Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr15_+_3270767 1.321 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr8_-_113848615 1.291 ENSMUST00000093113.4
 Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr15_+_82252397 1.224 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr6_+_86195214 1.187 ENSMUST00000032066.9
 Tgfa
transforming growth factor alpha
chr15_-_102722150 1.186 ENSMUST00000023818.3
 Calcoco1
calcium binding and coiled coil domain 1
chr15_-_102722120 1.176 ENSMUST00000171838.1
 Calcoco1
calcium binding and coiled coil domain 1
chr4_+_136286061 1.163 ENSMUST00000069195.4
ENSMUST00000130658.1
 Zfp46

zinc finger protein 46

chr4_+_126609818 1.096 ENSMUST00000097886.3
ENSMUST00000164362.1
 5730409E04Rik

RIKEN cDNA 5730409E04Rik gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.5 GO:0030279 negative regulation of ossification(GO:0030279)
0.2 3.6 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 3.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.3 2.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 2.1 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.1 1.9 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.5 1.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 1.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.4 1.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.3 1.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 1.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 1.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 1.2 GO:0015862 uridine transport(GO:0015862)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 1.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 1.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 1.0 GO:0097421 liver regeneration(GO:0097421)
0.1 1.0 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.7 GO:0016605 PML body(GO:0016605)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.0 GO:0043197 dendritic spine(GO:0043197)
0.2 1.9 GO:0045298 tubulin complex(GO:0045298)
0.3 1.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.3 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.2 1.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.1 0.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.4 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 0.4 GO:0070552 BRISC complex(GO:0070552)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.7 GO:0042805 actinin binding(GO:0042805)
1.5 4.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 2.8 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 2.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 1.3 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1 1.3 GO:0008430 selenium binding(GO:0008430)
0.0 1.3 GO:0017022 myosin binding(GO:0017022)
0.0 1.3 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 0.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.9 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.9 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)