Motif ID: Homez

Z-value: 0.965


Transcription factors associated with Homez:

Gene SymbolEntrez IDGene Name
Homez ENSMUSG00000057156.9 Homez

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Homezmm10_v2_chr14_-_54864055_548641580.385.7e-02Click!


Activity profile for motif Homez.

activity profile for motif Homez


Sorted Z-values histogram for motif Homez

Sorted Z-values for motif Homez



Network of associatons between targets according to the STRING database.



First level regulatory network of Homez

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 3.981 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr13_-_85127514 3.321 ENSMUST00000179230.1
 Gm4076
predicted gene 4076
chr4_-_117178726 2.774 ENSMUST00000153953.1
ENSMUST00000106436.1
 Kif2c

kinesin family member 2C

chr4_+_44300876 2.551 ENSMUST00000045607.5
 Melk
maternal embryonic leucine zipper kinase
chr4_+_115057683 2.427 ENSMUST00000161601.1
 Tal1
T cell acute lymphocytic leukemia 1
chr8_-_4779513 2.405 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr16_-_26989974 2.117 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr4_+_115057410 2.084 ENSMUST00000136946.1
 Tal1
T cell acute lymphocytic leukemia 1
chr2_+_71389239 2.063 ENSMUST00000028408.2
 Hat1
histone aminotransferase 1
chr9_-_36726374 1.968 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1


chr6_+_85587524 1.929 ENSMUST00000072018.5
 Alms1
Alstrom syndrome 1
chr18_+_50030977 1.911 ENSMUST00000145726.1
ENSMUST00000128377.1
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr3_-_63899437 1.800 ENSMUST00000159188.1
ENSMUST00000177143.1
 Plch1

phospholipase C, eta 1

chr17_+_87635974 1.740 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule
chr8_+_116921735 1.706 ENSMUST00000034205.4
 Cenpn
centromere protein N
chr3_+_5218516 1.692 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr1_-_163994767 1.665 ENSMUST00000097493.3
ENSMUST00000045876.6
 BC055324

cDNA sequence BC055324

chr19_-_36919606 1.598 ENSMUST00000057337.7
 Fgfbp3
fibroblast growth factor binding protein 3
chr3_+_5218546 1.594 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr5_-_8422695 1.592 ENSMUST00000171808.1
 Dbf4
DBF4 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 4.5 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.7 4.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 3.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.6 2.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 2.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 2.6 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 2.4 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.4 2.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 2.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.3 2.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.6 1.7 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.4 1.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.7 GO:0034508 centromere complex assembly(GO:0034508)
0.2 1.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.6 GO:0032611 interleukin-1 beta production(GO:0032611)
0.3 1.4 GO:0070829 heterochromatin maintenance(GO:0070829)
0.1 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.4 GO:0000578 embryonic axis specification(GO:0000578)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 4.5 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 3.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.1 2.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.3 GO:0005657 replication fork(GO:0005657)
0.0 2.3 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.5 1.9 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 1.8 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.5 1.4 GO:1990423 RZZ complex(GO:1990423)
0.1 1.4 GO:0001741 XY body(GO:0001741)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.2 GO:0042555 MCM complex(GO:0042555)
0.2 1.0 GO:0061702 inflammasome complex(GO:0061702)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 1.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.2 0.9 GO:0071817 MMXD complex(GO:0071817)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 4.1 GO:0070888 E-box binding(GO:0070888)
0.2 2.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.8 GO:0003682 chromatin binding(GO:0003682)
0.1 2.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.4 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.7 2.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 1.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.3 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 1.2 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 1.0 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)