Motif ID: Hoxa1

Z-value: 0.961


Transcription factors associated with Hoxa1:

Gene SymbolEntrez IDGene Name
Hoxa1 ENSMUSG00000029844.9 Hoxa1



Activity profile for motif Hoxa1.

activity profile for motif Hoxa1


Sorted Z-values histogram for motif Hoxa1

Sorted Z-values for motif Hoxa1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa1

PNG image of the network

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Top targets:


Showing 1 to 20 of 100 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_15239045 4.655 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr2_+_158375638 3.347 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr3_+_55782500 2.869 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr13_+_72628802 2.419 ENSMUST00000074372.4
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr2_+_163225363 2.321 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr10_+_81628702 2.130 ENSMUST00000129622.1
 Ankrd24
ankyrin repeat domain 24
chr5_-_135573036 1.832 ENSMUST00000004936.6
 Ccl24
chemokine (C-C motif) ligand 24
chr5_-_145201829 1.794 ENSMUST00000162220.1
ENSMUST00000031632.8
 Zkscan14

zinc finger with KRAB and SCAN domains 14

chr15_-_95528702 1.641 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr10_+_79988584 1.609 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr11_+_103774150 1.597 ENSMUST00000000127.5
 Wnt3
wingless-related MMTV integration site 3
chr14_+_70077375 1.596 ENSMUST00000035908.1
 Egr3
early growth response 3
chr8_-_11312731 1.593 ENSMUST00000033898.9
 Col4a1
collagen, type IV, alpha 1
chr13_+_72628831 1.581 ENSMUST00000169028.1
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr15_+_98167806 1.468 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr14_+_66344369 1.435 ENSMUST00000118426.1
ENSMUST00000121955.1
ENSMUST00000120229.1
ENSMUST00000134440.1
 Stmn4



stathmin-like 4



chr5_+_27261916 1.357 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr14_+_66344296 1.296 ENSMUST00000152093.1
ENSMUST00000074523.6
 Stmn4

stathmin-like 4

chr2_-_148045891 1.238 ENSMUST00000109964.1
 Foxa2
forkhead box A2
chrX_+_110814390 1.205 ENSMUST00000078229.3
 Pou3f4
POU domain, class 3, transcription factor 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.6 1.8 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.5 1.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 1.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 1.6 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of thymocyte aggregation(GO:2000400)
0.0 1.4 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 1.3 GO:0043084 penile erection(GO:0043084)
0.4 1.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 1.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 1.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.3 1.0 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.0 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.9 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.9 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.8 GO:0016578 histone deubiquitination(GO:0016578)
0.2 0.7 GO:0035633 maintenance of blood-brain barrier(GO:0035633)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 1.6 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 1.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.6 GO:0043204 perikaryon(GO:0043204)
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 1.6 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.4 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.4 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)