Motif ID: Hoxa10

Z-value: 0.655


Transcription factors associated with Hoxa10:

Gene SymbolEntrez IDGene Name
Hoxa10 ENSMUSG00000000938.11 Hoxa10



Activity profile for motif Hoxa10.

activity profile for motif Hoxa10


Sorted Z-values histogram for motif Hoxa10

Sorted Z-values for motif Hoxa10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa10

PNG image of the network

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Top targets:


Showing 1 to 20 of 140 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_44617310 2.935 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr6_+_34354119 2.211 ENSMUST00000038406.6
 Akr1b8
aldo-keto reductase family 1, member B8
chrX_+_96455359 2.019 ENSMUST00000033553.7
 Heph
hephaestin
chr4_+_115057683 1.996 ENSMUST00000161601.1
 Tal1
T cell acute lymphocytic leukemia 1
chr3_+_102010138 1.988 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr1_-_89933290 1.976 ENSMUST00000036954.7
 Gbx2
gastrulation brain homeobox 2
chr9_-_39604124 1.895 ENSMUST00000042485.4
ENSMUST00000141370.1
 AW551984

expressed sequence AW551984

chr8_+_106935720 1.828 ENSMUST00000047425.3
 Sntb2
syntrophin, basic 2
chr4_+_115057410 1.421 ENSMUST00000136946.1
 Tal1
T cell acute lymphocytic leukemia 1
chr17_+_29093763 1.399 ENSMUST00000023829.6
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr2_-_51149100 1.246 ENSMUST00000154545.1
ENSMUST00000017288.2
 Rnd3

Rho family GTPase 3

chr6_-_3494587 1.195 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr1_+_74713551 1.174 ENSMUST00000027356.5
 Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr13_+_24614608 0.940 ENSMUST00000091694.3
 Fam65b
family with sequence similarity 65, member B
chr2_+_102658640 0.832 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_+_115042752 0.762 ENSMUST00000134140.2
 Mir17hg
Mir17 host gene 1 (non-protein coding)
chr9_-_100506844 0.684 ENSMUST00000112874.3
 Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr11_-_78984831 0.666 ENSMUST00000073001.4
ENSMUST00000108269.3
 Lgals9

lectin, galactose binding, soluble 9

chr13_+_44840686 0.654 ENSMUST00000173906.1
 Jarid2
jumonji, AT rich interactive domain 2
chr9_-_119825456 0.641 ENSMUST00000070617.7
 Scn11a
sodium channel, voltage-gated, type XI, alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.7 2.2 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.3 2.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 2.0 GO:0006825 copper ion transport(GO:0006825)
0.1 2.0 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 1.9 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 1.4 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.4 1.3 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 1.2 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 1.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.8 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.2 0.7 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 0.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.6 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.6 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.6 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.4 GO:0033193 Lsd1/2 complex(GO:0033193)
0.5 1.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.3 1.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 0.8 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.1 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 0.6 GO:0044299 C-fiber(GO:0044299)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 GO:0070888 E-box binding(GO:0070888)
0.2 2.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 2.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.4 2.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 2.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)