Motif ID: Hoxa5

Z-value: 1.148


Transcription factors associated with Hoxa5:

Gene SymbolEntrez IDGene Name
Hoxa5 ENSMUSG00000038253.6 Hoxa5



Activity profile for motif Hoxa5.

activity profile for motif Hoxa5


Sorted Z-values histogram for motif Hoxa5

Sorted Z-values for motif Hoxa5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_25882407 3.878 ENSMUST00000163316.2
 Gm6434
predicted gene 6434
chr15_-_81843699 3.705 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chrY_+_1010543 3.092 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr10_-_96409038 2.764 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091
chr18_-_9726670 2.731 ENSMUST00000171339.1
 Gm17430
predicted gene, 17430
chr9_+_17030045 2.606 ENSMUST00000164523.2
 Gm5611
predicted gene 5611
chrX_+_66653003 2.500 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chrY_-_1286563 2.459 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr19_-_50030735 2.160 ENSMUST00000071866.1
 Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr11_+_16752203 1.903 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chr17_-_31636631 1.863 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
 Cbs


cystathionine beta-synthase


chr11_-_83645621 1.856 ENSMUST00000182502.1
 Rpl9-ps1
ribosomal protein L9, pseudogene 1
chr19_-_34255325 1.786 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chr12_+_32953874 1.715 ENSMUST00000076698.5
 Sypl
synaptophysin-like protein
chr12_+_12911986 1.664 ENSMUST00000085720.1
 Rpl36-ps3
ribosomal protein L36, pseudogene 3
chr6_+_127233756 1.650 ENSMUST00000071458.3
 Gm4968
predicted gene 4968
chr5_+_17574268 1.639 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_3343893 1.567 ENSMUST00000165117.1
 Cdk6
cyclin-dependent kinase 6
chr10_-_13324250 1.503 ENSMUST00000105543.1
 Phactr2
phosphatase and actin regulator 2
chr9_-_36726374 1.502 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 198 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 4.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 3.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.7 2.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 2.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.8 2.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.1 2.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 2.0 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.5 1.9 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 1.8 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 1.7 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.5 1.6 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.3 1.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 1.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 1.5 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.3 1.3 GO:0042938 dipeptide transport(GO:0042938)
0.3 1.3 GO:1902309 positive regulation of mast cell chemotaxis(GO:0060754) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 1.3 GO:0035329 hippo signaling(GO:0035329)
0.4 1.2 GO:1990705 cholangiocyte proliferation(GO:1990705)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.8 GO:0000793 condensed chromosome(GO:0000793)
0.6 1.9 GO:0031983 vesicle lumen(GO:0031983)
0.4 1.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.8 GO:0000776 kinetochore(GO:0000776)
0.0 1.8 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.2 1.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.5 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 1.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 1.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.1 GO:0098536 deuterosome(GO:0098536)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 112 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 4.0 GO:0038191 neuropilin binding(GO:0038191)
0.0 3.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.6 1.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.6 1.9 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 1.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 1.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.6 GO:0030332 cyclin binding(GO:0030332)
0.5 1.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 1.3 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.3 1.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 1.3 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.4 1.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 1.0 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)