Motif ID: Hoxa6

Z-value: 0.544


Transcription factors associated with Hoxa6:

Gene SymbolEntrez IDGene Name
Hoxa6 ENSMUSG00000043219.8 Hoxa6



Activity profile for motif Hoxa6.

activity profile for motif Hoxa6


Sorted Z-values histogram for motif Hoxa6

Sorted Z-values for motif Hoxa6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa6

PNG image of the network

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Top targets:


Showing 1 to 20 of 182 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_55894508 3.867 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr13_+_94875600 2.145 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr1_+_6730051 1.957 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr14_-_48665098 1.469 ENSMUST00000118578.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr1_+_19212054 1.359 ENSMUST00000064976.4
 Tfap2b
transcription factor AP-2 beta
chr2_-_28916412 1.350 ENSMUST00000050776.2
ENSMUST00000113849.1
 Barhl1

BarH-like 1 (Drosophila)

chr7_-_70366735 1.218 ENSMUST00000089565.5
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr6_+_15196949 1.185 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
 Foxp2



forkhead box P2



chr2_-_28916668 1.093 ENSMUST00000113847.1
 Barhl1
BarH-like 1 (Drosophila)
chr6_-_138426735 1.090 ENSMUST00000162932.1
 Lmo3
LIM domain only 3
chr2_+_70474923 1.077 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chr14_+_75455957 1.046 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr1_+_6734827 1.041 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr1_+_19103022 1.021 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr1_+_187997835 1.003 ENSMUST00000110938.1
 Esrrg
estrogen-related receptor gamma
chr7_-_49636847 0.956 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr1_+_187997821 0.956 ENSMUST00000027906.6
 Esrrg
estrogen-related receptor gamma
chr10_+_88091070 0.938 ENSMUST00000048621.7
 Pmch
pro-melanin-concentrating hormone
chr10_-_45470201 0.932 ENSMUST00000079390.6
 Lin28b
lin-28 homolog B (C. elegans)
chr3_+_102010138 0.887 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 4.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 3.4 GO:0030901 midbrain development(GO:0030901)
0.7 2.7 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 2.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 1.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 1.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.5 1.4 GO:0097274 urea homeostasis(GO:0097274)
0.2 1.2 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 1.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 1.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 1.0 GO:0060539 diaphragm development(GO:0060539)
0.1 1.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.3 0.9 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 0.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.9 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.9 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.5 GO:0005667 transcription factor complex(GO:0005667)
0.5 4.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0008623 CHRAC(GO:0008623)
0.0 0.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.2 GO:0044299 C-fiber(GO:0044299)
0.1 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.0 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.2 4.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 2.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.0 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.8 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)