Motif ID: Hoxa7_Hoxc8

Z-value: 0.560

Transcription factors associated with Hoxa7_Hoxc8:

Gene SymbolEntrez IDGene Name
Hoxa7 ENSMUSG00000038236.6 Hoxa7
Hoxc8 ENSMUSG00000001657.6 Hoxc8






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa7_Hoxc8

PNG image of the network

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Top targets:


Showing 1 to 20 of 92 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_86548268 2.627 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr3_+_55782500 1.770 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr8_+_45885479 1.393 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr19_+_55895508 1.286 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr14_+_80000292 1.277 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr1_+_72284367 1.228 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr15_-_37458523 1.123 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr5_-_62766153 1.064 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_-_143933204 0.868 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chrX_-_143933089 0.840 ENSMUST00000087313.3
Dcx
doublecortin
chr15_-_8710409 0.791 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710734 0.781 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_125136692 0.725 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr18_+_23753708 0.714 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr3_+_55461758 0.672 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr2_+_109917639 0.667 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr6_-_118479237 0.647 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr3_+_5218516 0.638 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr6_+_30541582 0.616 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr13_+_43785107 0.614 ENSMUST00000015540.2
Cd83
CD83 antigen

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.4 1.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 1.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.2 0.7 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 0.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.1 1.6 GO:0043205 fibril(GO:0043205)
0.1 1.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.3 GO:0042581 specific granule(GO:0042581)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 1.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 1.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 0.4 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.4 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)