Motif ID: Hoxa7_Hoxc8
Z-value: 0.560
Transcription factors associated with Hoxa7_Hoxc8:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxa7 | ENSMUSG00000038236.6 | Hoxa7 |
Hoxc8 | ENSMUSG00000001657.6 | Hoxc8 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.6 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.2 | 0.7 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.2 | 1.3 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.1 | 0.4 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.1 | 2.8 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.1 | 0.6 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
0.1 | 1.7 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.1 | 0.4 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.1 | 0.3 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.1 | 0.2 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
0.1 | 0.3 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.1 | 0.4 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 0.3 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
0.1 | 0.2 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.0 | 0.4 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) |
0.0 | 0.3 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.0 | 0.1 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.0 | 0.2 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
0.0 | 0.5 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 1.3 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 0.4 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.2 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
0.0 | 0.1 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.0 | 0.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.0 | 0.3 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.0 | 0.6 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.0 | 1.1 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.0 | 0.4 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
0.0 | 0.0 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.3 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 1.6 | GO:0043205 | fibril(GO:0043205) |
0.1 | 1.3 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 0.2 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.4 | GO:0097433 | dense body(GO:0097433) |
0.0 | 0.2 | GO:0033503 | HULC complex(GO:0033503) |
0.0 | 0.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 0.2 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.2 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 1.8 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.4 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.0 | 0.0 | GO:0005594 | collagen type IX trimer(GO:0005594) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.6 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.1 | 0.4 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.1 | 0.2 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
0.1 | 1.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 1.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 0.3 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.1 | 0.7 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 1.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 0.3 | GO:0070330 | aromatase activity(GO:0070330) |
0.1 | 0.4 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 0.4 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.2 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.0 | 0.2 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.0 | 0.4 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 1.1 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 1.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 1.3 | GO:0045296 | cadherin binding(GO:0045296) |
0.0 | 0.2 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 0.4 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.0 | 0.2 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 0.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 0.4 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
0.0 | 0.6 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.0 | 0.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |