Motif ID: Hoxb1

Z-value: 0.463


Transcription factors associated with Hoxb1:

Gene SymbolEntrez IDGene Name
Hoxb1 ENSMUSG00000018973.2 Hoxb1



Activity profile for motif Hoxb1.

activity profile for motif Hoxb1


Sorted Z-values histogram for motif Hoxb1

Sorted Z-values for motif Hoxb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 69 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_119053339 2.495 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr1_-_119053619 1.466 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr3_+_127633134 1.347 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr14_-_69284982 1.326 ENSMUST00000183882.1
ENSMUST00000037064.4
Slc25a37

solute carrier family 25, member 37

chr5_-_24527276 1.117 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr8_-_87959560 0.983 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr7_+_73391160 0.973 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr9_+_65890237 0.963 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr2_+_84840612 0.934 ENSMUST00000111625.1
Slc43a1
solute carrier family 43, member 1
chr14_-_69503220 0.657 ENSMUST00000180059.2
Gm21464
predicted gene, 21464
chrX_+_110814390 0.613 ENSMUST00000078229.3
Pou3f4
POU domain, class 3, transcription factor 4
chr10_-_63421739 0.598 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr3_-_65958236 0.558 ENSMUST00000029416.7
Ccnl1
cyclin L1
chr8_+_84901928 0.529 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr4_-_91399984 0.492 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_+_103114385 0.456 ENSMUST00000106858.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr4_-_103114238 0.452 ENSMUST00000036451.8
ENSMUST00000036557.8
Wdr78

WD repeat domain 78

chr10_+_67185730 0.446 ENSMUST00000173689.1
Jmjd1c
jumonji domain containing 1C
chr5_+_139543889 0.443 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr4_-_103114555 0.429 ENSMUST00000106868.3
Wdr78
WD repeat domain 78

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 4.0 GO:0060032 notochord regression(GO:0060032)
0.0 1.3 GO:0021954 central nervous system neuron development(GO:0021954)
0.3 1.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 1.0 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.0 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.7 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.7 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.1 0.6 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 0.6 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.6 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.4 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.3 GO:1905154 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.0 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular_function category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.1 1.0 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 0.8 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) procollagen-proline dioxygenase activity(GO:0019798) peptidyl-proline dioxygenase activity(GO:0031543) hypophosphite dioxygenase activity(GO:0034792) DNA-N1-methyladenine dioxygenase activity(GO:0043734) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)