Motif ID: Hoxb4

Z-value: 0.308


Transcription factors associated with Hoxb4:

Gene SymbolEntrez IDGene Name
Hoxb4 ENSMUSG00000038692.7 Hoxb4



Activity profile for motif Hoxb4.

activity profile for motif Hoxb4


Sorted Z-values histogram for motif Hoxb4

Sorted Z-values for motif Hoxb4



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_78968079 0.842 ENSMUST00000049117.5
 Gm5830
predicted pseudogene 5830
chr1_+_159737510 0.789 ENSMUST00000111669.3
 Tnr
tenascin R
chr12_+_58211772 0.745 ENSMUST00000110671.2
ENSMUST00000044299.2
 Sstr1

somatostatin receptor 1

chrX_-_143933204 0.578 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chrX_-_143933089 0.577 ENSMUST00000087313.3
 Dcx
doublecortin
chr11_+_85353156 0.496 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
 Bcas3





breast carcinoma amplified sequence 3





chr13_+_94083490 0.390 ENSMUST00000156071.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr16_-_94370450 0.366 ENSMUST00000138514.1
 Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr3_-_37125943 0.357 ENSMUST00000029275.5
 Il2
interleukin 2
chr19_+_4711153 0.313 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr8_+_83666827 0.250 ENSMUST00000019608.5
 Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr4_+_43493345 0.249 ENSMUST00000030181.5
ENSMUST00000107922.2
 Ccdc107

coiled-coil domain containing 107

chrX_+_166344692 0.216 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr10_-_59616667 0.211 ENSMUST00000020312.6
 Mcu
mitochondrial calcium uniporter
chr7_-_30232186 0.190 ENSMUST00000006254.5
 Tbcb
tubulin folding cofactor B
chr1_+_146497614 0.163 ENSMUST00000132847.1
ENSMUST00000166814.1
 Brinp3

bone morphogenetic protein/retinoic acid inducible neural specific 3

chr7_+_28693032 0.157 ENSMUST00000151227.1
ENSMUST00000108281.1
 Fbxo27

F-box protein 27

chr7_+_30232310 0.153 ENSMUST00000108193.1
ENSMUST00000108192.1
 Polr2i

polymerase (RNA) II (DNA directed) polypeptide I

chr1_-_171222435 0.151 ENSMUST00000147246.1
ENSMUST00000111326.1
ENSMUST00000138184.1
 Tomm40l


translocase of outer mitochondrial membrane 40 homolog-like (yeast)


chr5_+_143363890 0.130 ENSMUST00000010969.8
 Grid2ip
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chr7_+_30232032 0.126 ENSMUST00000149654.1
 Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr16_-_37384915 0.124 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr12_-_15816762 0.115 ENSMUST00000020922.7
 Trib2
tribbles homolog 2 (Drosophila)
chr2_-_38714491 0.090 ENSMUST00000028084.4
 Nr5a1
nuclear receptor subfamily 5, group A, member 1
chr18_-_56562187 0.070 ENSMUST00000171844.2
 Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr16_+_78930940 0.061 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr1_-_171222508 0.059 ENSMUST00000005817.2
 Tomm40l
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr17_+_57279094 0.045 ENSMUST00000169220.2
ENSMUST00000005889.9
ENSMUST00000112870.4
 Vav1


vav 1 oncogene


chr16_-_37384940 0.035 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chr2_-_84775420 0.026 ENSMUST00000111641.1
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.2 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 1.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0072534 perineuronal net(GO:0072534)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.1 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.2 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 1.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0015288 porin activity(GO:0015288)