Motif ID: Hoxb5

Z-value: 1.227


Transcription factors associated with Hoxb5:

Gene SymbolEntrez IDGene Name
Hoxb5 ENSMUSG00000038700.3 Hoxb5



Activity profile for motif Hoxb5.

activity profile for motif Hoxb5


Sorted Z-values histogram for motif Hoxb5

Sorted Z-values for motif Hoxb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb5

PNG image of the network

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Top targets:


Showing 1 to 20 of 90 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_125532377 11.276 ENSMUST00000031446.6
 Tmem132b
transmembrane protein 132B
chr6_-_18514802 6.503 ENSMUST00000090601.5
 Cttnbp2
cortactin binding protein 2
chr1_-_56971762 5.349 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr17_-_57087729 5.124 ENSMUST00000071135.5
 Tubb4a
tubulin, beta 4A class IVA
chr17_+_35076902 4.804 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr12_-_78980758 4.278 ENSMUST00000174072.1
 Tmem229b
transmembrane protein 229B
chr11_+_74619594 3.953 ENSMUST00000100866.2
 E130309D14Rik
RIKEN cDNA E130309D14 gene
chr17_+_35077080 3.861 ENSMUST00000172959.1
 Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr12_-_78983476 3.821 ENSMUST00000070174.7
 Tmem229b
transmembrane protein 229B
chr2_+_158667119 3.763 ENSMUST00000045503.4
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr19_-_45816007 3.469 ENSMUST00000079431.3
ENSMUST00000026247.6
ENSMUST00000162528.2
 Kcnip2


Kv channel-interacting protein 2


chr3_-_85722474 3.070 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chrX_-_165327376 3.054 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr7_+_3390629 2.570 ENSMUST00000182222.1
 Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chr10_-_62143906 2.422 ENSMUST00000141724.1
ENSMUST00000150057.1
 2010107G23Rik

RIKEN cDNA 2010107G23 gene

chr2_-_153225396 2.398 ENSMUST00000099194.2
 Tspyl3
TSPY-like 3
chr5_+_117133567 2.311 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
 Taok3


TAO kinase 3


chr3_-_89160155 2.150 ENSMUST00000029686.3
 Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr11_+_97798995 1.982 ENSMUST00000143571.1
 Lasp1
LIM and SH3 protein 1
chr13_+_88821472 1.889 ENSMUST00000118731.1
ENSMUST00000081769.6
 Edil3

EGF-like repeats and discoidin I-like domains 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.7 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.3 5.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.9 3.8 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 3.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 3.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.7 3.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 3.1 GO:0071361 cellular response to zinc ion(GO:0071294) cellular response to ethanol(GO:0071361)
0.7 2.8 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.1 2.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 2.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 2.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 2.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.5 1.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.3 1.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 1.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.7 GO:0008021 synaptic vesicle(GO:0008021)
0.1 5.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.6 5.1 GO:0033269 internode region of axon(GO:0033269)
0.0 3.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 3.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 3.2 GO:0043204 perikaryon(GO:0043204)
0.1 2.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 2.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.3 GO:0016342 catenin complex(GO:0016342)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.0 1.1 GO:0030496 midbody(GO:0030496)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 8.7 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.8 6.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 5.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 3.8 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.7 3.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 3.7 GO:0005178 integrin binding(GO:0005178)
0.0 3.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
1.0 3.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 2.9 GO:0016247 channel regulator activity(GO:0016247)
0.5 2.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.4 2.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 2.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 2.0 GO:0051015 actin filament binding(GO:0051015)
0.1 1.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 1.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 1.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 1.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.3 GO:0030552 cAMP binding(GO:0030552)