Motif ID: Hoxb6

Z-value: 0.347


Transcription factors associated with Hoxb6:

Gene SymbolEntrez IDGene Name
Hoxb6 ENSMUSG00000000690.4 Hoxb6



Activity profile for motif Hoxb6.

activity profile for motif Hoxb6


Sorted Z-values histogram for motif Hoxb6

Sorted Z-values for motif Hoxb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 1.129 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr12_-_119238794 0.871 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr4_+_15881255 0.759 ENSMUST00000029876.1
Calb1
calbindin 1
chr8_-_105471481 0.638 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr10_-_58675631 0.620 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr13_-_85127514 0.563 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr14_+_32599922 0.494 ENSMUST00000068938.5
Prrxl1
paired related homeobox protein-like 1
chr19_+_25406661 0.478 ENSMUST00000146647.1
Kank1
KN motif and ankyrin repeat domains 1
chr6_-_3494587 0.433 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr2_-_125859139 0.384 ENSMUST00000110463.1
ENSMUST00000028635.5
Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

chr2_+_164769892 0.376 ENSMUST00000088248.6
ENSMUST00000001439.6
Ube2c

ubiquitin-conjugating enzyme E2C

chr3_-_100969644 0.376 ENSMUST00000076941.5
Ttf2
transcription termination factor, RNA polymerase II
chr9_+_96258697 0.325 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr6_-_12109583 0.285 ENSMUST00000080891.5
Gm6578
predicted gene 6578
chr3_+_66985647 0.285 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr1_-_45503282 0.269 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr7_+_51880312 0.250 ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr15_+_34306666 0.219 ENSMUST00000163455.2
ENSMUST00000022947.5
Matn2

matrilin 2

chr16_+_44347121 0.214 ENSMUST00000050897.6
Spice1
spindle and centriole associated protein 1
chr3_+_94413244 0.183 ENSMUST00000166032.1
ENSMUST00000045245.5
Tdrkh

tudor and KH domain containing protein

chr3_-_119783262 0.166 ENSMUST00000029780.7
Ptbp2
polypyrimidine tract binding protein 2
chr3_+_66985680 0.161 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chrX_+_140367494 0.157 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr11_-_69795930 0.157 ENSMUST00000045971.8
Chrnb1
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr3_-_116712644 0.150 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr19_-_6925367 0.149 ENSMUST00000057716.4
Tex40
testis expressed 40
chr11_-_72215592 0.134 ENSMUST00000021157.8
Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr9_+_92309362 0.134 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr3_-_94412883 0.128 ENSMUST00000181305.1
1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr8_+_31111816 0.124 ENSMUST00000046941.7
Rnf122
ring finger protein 122
chr11_-_74724670 0.107 ENSMUST00000021091.8
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr2_+_125859134 0.105 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2

galactokinase 2

chr9_-_35570393 0.104 ENSMUST00000115110.4
Hyls1
hydrolethalus syndrome 1
chr8_-_77610668 0.089 ENSMUST00000141202.1
ENSMUST00000152168.1
Tmem184c

transmembrane protein 184C

chr10_+_72309225 0.086 ENSMUST00000061324.4
Gm9923
predicted pseudogene 9923
chr19_+_24875679 0.086 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr8_-_77610597 0.077 ENSMUST00000034030.8
Tmem184c
transmembrane protein 184C
chrX_-_101222426 0.059 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr9_+_21955747 0.036 ENSMUST00000053583.5
Swsap1
SWIM type zinc finger 7 associated protein 1
chr6_+_86371489 0.033 ENSMUST00000089558.5
Snrpg
small nuclear ribonucleoprotein polypeptide G
chr11_-_96977660 0.011 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2

Sp2 transcription factor

chr13_+_93304066 0.008 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr5_+_31526989 0.001 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
Slc4a1ap


solute carrier family 4 (anion exchanger), member 1, adaptor protein



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.5 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 0.6 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.5 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.8 GO:0007614 short-term memory(GO:0007614)
0.0 0.9 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.0 0.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.9 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.8 GO:0019842 vitamin binding(GO:0019842)