Motif ID: Hoxc10

Z-value: 0.753


Transcription factors associated with Hoxc10:

Gene SymbolEntrez IDGene Name
Hoxc10 ENSMUSG00000022484.7 Hoxc10



Activity profile for motif Hoxc10.

activity profile for motif Hoxc10


Sorted Z-values histogram for motif Hoxc10

Sorted Z-values for motif Hoxc10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc10

PNG image of the network

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Top targets:


Showing 1 to 20 of 90 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_159737510 6.598 ENSMUST00000111669.3
 Tnr
tenascin R
chr5_+_117841839 4.512 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr16_-_23988852 3.730 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr6_-_13839916 3.046 ENSMUST00000060442.7
 Gpr85
G protein-coupled receptor 85
chr2_-_25469742 2.773 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr13_-_84064772 2.765 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr15_+_21111452 2.730 ENSMUST00000075132.6
 Cdh12
cadherin 12
chr18_-_42899470 2.504 ENSMUST00000120632.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_-_42899294 2.452 ENSMUST00000117687.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr4_+_144893127 1.955 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_-_36104060 1.890 ENSMUST00000112961.3
ENSMUST00000112966.3
 Lhx6

LIM homeobox protein 6

chr2_-_25470031 1.884 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr15_+_81936753 1.751 ENSMUST00000038757.7
 Csdc2
cold shock domain containing C2, RNA binding
chr15_+_81936911 1.739 ENSMUST00000135663.1
 Csdc2
cold shock domain containing C2, RNA binding
chr15_+_92597104 1.648 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr2_+_178141920 1.593 ENSMUST00000103066.3
 Phactr3
phosphatase and actin regulator 3
chr17_-_90088343 1.561 ENSMUST00000173917.1
 Nrxn1
neurexin I
chr17_-_91092715 1.471 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr15_-_58214882 1.463 ENSMUST00000022986.6
 Fbxo32
F-box protein 32
chr17_+_31433054 1.455 ENSMUST00000136384.1
 Pde9a
phosphodiesterase 9A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 6.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.7 5.0 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.9 4.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.1 4.5 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
1.2 3.7 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.6 3.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 2.0 GO:0042572 retinol metabolic process(GO:0042572)
0.3 1.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.7 GO:0007097 nuclear migration(GO:0007097)
0.5 1.5 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.4 GO:0048679 regulation of axon regeneration(GO:0048679)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.2 1.2 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.4 1.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092) positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 1.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 1.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 6.6 GO:0072534 perineuronal net(GO:0072534)
0.1 5.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 4.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 4.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 3.7 GO:0005657 replication fork(GO:0005657)
0.0 2.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0042641 actomyosin(GO:0042641)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 0.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 0.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0032585 multivesicular body membrane(GO:0032585)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.6 GO:0046625 sphingolipid binding(GO:0046625)
0.4 5.0 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
1.2 4.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.5 4.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 3.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 3.0 GO:0005057 receptor signaling protein activity(GO:0005057)
0.3 2.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 1.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.4 GO:0002162 dystroglycan binding(GO:0002162)
0.4 1.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 1.2 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.1 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 1.1 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.3 1.0 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)