Motif ID: Hoxc13_Hoxd13

Z-value: 0.789




Activity profile for motif Hoxc13_Hoxd13.

activity profile for motif Hoxc13_Hoxd13


Sorted Z-values histogram for motif Hoxc13_Hoxd13

Sorted Z-values for motif Hoxc13_Hoxd13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc13_Hoxd13

PNG image of the network

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Top targets:


Showing 1 to 20 of 80 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_56978534 6.055 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr10_-_8518801 4.683 ENSMUST00000061601.7
 Ust
uronyl-2-sulfotransferase
chr5_+_17574268 3.707 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_+_108213086 3.524 ENSMUST00000032192.6
 Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr16_-_74411776 3.261 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr18_+_69346143 2.532 ENSMUST00000114980.1
 Tcf4
transcription factor 4
chr17_+_75178911 2.276 ENSMUST00000112514.1
 Ltbp1
latent transforming growth factor beta binding protein 1
chr14_-_118052235 1.973 ENSMUST00000022725.2
 Dct
dopachrome tautomerase
chr13_+_16014457 1.932 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr17_+_75178797 1.902 ENSMUST00000112516.1
ENSMUST00000135447.1
 Ltbp1

latent transforming growth factor beta binding protein 1

chr9_+_32696005 1.056 ENSMUST00000034534.6
ENSMUST00000050797.7
ENSMUST00000184887.1
 Ets1


E26 avian leukemia oncogene 1, 5' domain


chr3_-_142169311 1.012 ENSMUST00000106230.1
 Bmpr1b
bone morphogenetic protein receptor, type 1B
chr17_-_6477102 0.991 ENSMUST00000167717.2
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr16_+_23226014 0.971 ENSMUST00000178797.1
 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr8_+_112570043 0.859 ENSMUST00000034225.6
ENSMUST00000118171.1
 Cntnap4

contactin associated protein-like 4

chr7_-_73537621 0.857 ENSMUST00000172704.1
 Chd2
chromodomain helicase DNA binding protein 2
chr8_+_83666827 0.842 ENSMUST00000019608.5
 Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr3_+_126597415 0.800 ENSMUST00000066452.7
ENSMUST00000171289.1
ENSMUST00000106399.1
 Camk2d


calcium/calmodulin-dependent protein kinase II, delta


chr16_-_57231434 0.785 ENSMUST00000023431.6
 Tbc1d23
TBC1 domain family, member 23
chr3_-_142169196 0.778 ENSMUST00000098568.1
 Bmpr1b
bone morphogenetic protein receptor, type 1B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 3.8 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.5 3.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.6 3.5 GO:0042045 epithelial fluid transport(GO:0042045)
1.1 3.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 3.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.3 2.5 GO:0042118 endothelial cell activation(GO:0042118)
0.3 2.0 GO:0006570 tyrosine metabolic process(GO:0006570)
0.4 1.9 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.4 1.9 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.4 1.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 1.5 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.3 1.1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 1.0 GO:1990743 protein sialylation(GO:1990743)
0.1 0.9 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.8 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 0.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.6 GO:0009405 pathogenesis(GO:0009405)
0.1 0.6 GO:1901475 pyruvate transmembrane transport(GO:1901475)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.6 GO:0000118 histone deacetylase complex(GO:0000118)
1.4 4.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.2 3.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 3.3 GO:0030673 axolemma(GO:0030673)
0.1 2.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.6 1.9 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.8 GO:0043194 axon initial segment(GO:0043194)
0.0 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.7 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
1.0 4.2 GO:0050436 microfibril binding(GO:0050436)
0.3 3.7 GO:0038191 neuropilin binding(GO:0038191)
1.2 3.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 3.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 2.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.3 1.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 1.5 GO:0031432 titin binding(GO:0031432)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.2 0.8 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.6 GO:0015643 toxic substance binding(GO:0015643)