Motif ID: Hoxc6

Z-value: 0.318


Transcription factors associated with Hoxc6:

Gene SymbolEntrez IDGene Name
Hoxc6 ENSMUSG00000001661.4 Hoxc6



Activity profile for motif Hoxc6.

activity profile for motif Hoxc6


Sorted Z-values histogram for motif Hoxc6

Sorted Z-values for motif Hoxc6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_19208914 1.273 ENSMUST00000027059.4
 Tfap2b
transcription factor AP-2 beta
chr3_+_129213920 0.646 ENSMUST00000042587.10
 Pitx2
paired-like homeodomain transcription factor 2
chr3_+_5218546 0.633 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr3_+_5218516 0.564 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr3_+_5218589 0.529 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr3_+_66985700 0.514 ENSMUST00000046542.6
ENSMUST00000162693.1
 Rsrc1

arginine/serine-rich coiled-coil 1

chr6_-_65144908 0.467 ENSMUST00000031982.4
 Hpgds
hematopoietic prostaglandin D synthase
chr3_+_66985647 0.456 ENSMUST00000162362.1
ENSMUST00000065074.7
 Rsrc1

arginine/serine-rich coiled-coil 1

chr2_-_51149100 0.421 ENSMUST00000154545.1
ENSMUST00000017288.2
 Rnd3

Rho family GTPase 3

chr6_-_3494587 0.392 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr3_+_66985680 0.342 ENSMUST00000065047.6
 Rsrc1
arginine/serine-rich coiled-coil 1
chr9_-_27155418 0.328 ENSMUST00000167074.1
ENSMUST00000034472.8
 Jam3

junction adhesion molecule 3

chr15_+_44619551 0.286 ENSMUST00000022964.7
 Ebag9
estrogen receptor-binding fragment-associated gene 9
chr5_-_110046486 0.280 ENSMUST00000167969.1
 Gm17655
predicted gene, 17655
chr10_-_53647080 0.209 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr7_+_123123870 0.207 ENSMUST00000094053.5
 Tnrc6a
trinucleotide repeat containing 6a
chr4_+_132351768 0.193 ENSMUST00000172202.1
 Gm17300
predicted gene, 17300
chrX_-_94212638 0.181 ENSMUST00000113922.1
 Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr4_-_132351636 0.180 ENSMUST00000105951.1
 Rcc1
regulator of chromosome condensation 1
chr9_-_21760275 0.175 ENSMUST00000098942.4
 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr5_-_128953303 0.172 ENSMUST00000111346.1
 Rimbp2
RIMS binding protein 2
chr11_-_26210553 0.167 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chrX_-_94212685 0.156 ENSMUST00000050328.8
 Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr10_+_37139558 0.149 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr19_+_32619997 0.148 ENSMUST00000025833.6
 Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chrX_-_136741155 0.140 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
 Morf4l2




mortality factor 4 like 2




chr16_-_56712825 0.123 ENSMUST00000136394.1
 Tfg
Trk-fused gene
chr19_+_24875679 0.117 ENSMUST00000073080.5
 Gm10053
predicted gene 10053
chrM_-_14060 0.117 ENSMUST00000082419.1
 mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr15_+_100154379 0.104 ENSMUST00000023768.6
ENSMUST00000108971.2
 Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)

chr11_-_23895208 0.100 ENSMUST00000102863.2
ENSMUST00000020513.3
 Papolg

poly(A) polymerase gamma

chr6_+_128399881 0.100 ENSMUST00000120405.1
 Nrip2
nuclear receptor interacting protein 2
chr10_-_61784014 0.097 ENSMUST00000020283.4
 H2afy2
H2A histone family, member Y2
chr10_-_100589205 0.091 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr10_+_61175206 0.091 ENSMUST00000079235.5
 Tbata
thymus, brain and testes associated
chr10_-_58718210 0.089 ENSMUST00000169859.1
 Gm17542
predicted gene, 17542
chr17_-_35115428 0.087 ENSMUST00000172854.1
ENSMUST00000062657.4
 Ly6g5b

lymphocyte antigen 6 complex, locus G5B

chr17_-_78985428 0.084 ENSMUST00000118991.1
 Prkd3
protein kinase D3
chr11_-_109472611 0.078 ENSMUST00000168740.1
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chrM_+_14138 0.077 ENSMUST00000082421.1
 mt-Cytb
mitochondrially encoded cytochrome b
chr15_-_50889043 0.070 ENSMUST00000183997.1
ENSMUST00000183757.1
 Trps1

trichorhinophalangeal syndrome I (human)

chr8_-_9976294 0.069 ENSMUST00000095476.4
 Lig4
ligase IV, DNA, ATP-dependent
chr6_+_128399766 0.067 ENSMUST00000001561.5
 Nrip2
nuclear receptor interacting protein 2
chr3_+_151437887 0.066 ENSMUST00000046977.7
 Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr15_+_91673175 0.060 ENSMUST00000060642.6
 Lrrk2
leucine-rich repeat kinase 2
chr16_-_21995478 0.048 ENSMUST00000074230.4
ENSMUST00000060673.6
 Liph

lipase, member H

chr19_+_6364557 0.043 ENSMUST00000155973.1
 Sf1
splicing factor 1
chr10_-_70655934 0.043 ENSMUST00000162144.1
ENSMUST00000162793.1
 Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr7_-_115846080 0.041 ENSMUST00000166207.1
 Sox6
SRY-box containing gene 6
chr9_+_107551516 0.041 ENSMUST00000093786.2
ENSMUST00000122225.1
 Rassf1

Ras association (RalGDS/AF-6) domain family member 1

chr6_+_36388055 0.039 ENSMUST00000172278.1
 Chrm2
cholinergic receptor, muscarinic 2, cardiac
chr10_-_37138863 0.036 ENSMUST00000092584.5
 Marcks
myristoylated alanine rich protein kinase C substrate
chr6_-_30693676 0.034 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
 Cep41



centrosomal protein 41



chr7_-_19604444 0.029 ENSMUST00000086041.5
 Clasrp
CLK4-associating serine/arginine rich protein
chr7_-_24299310 0.024 ENSMUST00000145131.1
 Zfp61
zinc finger protein 61
chr10_-_62449738 0.005 ENSMUST00000020273.9
 Supv3l1
suppressor of var1, 3-like 1 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0097274 urea homeostasis(GO:0097274)
0.2 0.6 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1 0.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.0 1.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:1903351 regulation of protein autoubiquitination(GO:1902498) response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)