Motif ID: Hoxc9

Z-value: 0.565


Transcription factors associated with Hoxc9:

Gene SymbolEntrez IDGene Name
Hoxc9 ENSMUSG00000036139.6 Hoxc9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxc9mm10_v2_chr15_+_102977032_102977032-0.301.4e-01Click!


Activity profile for motif Hoxc9.

activity profile for motif Hoxc9


Sorted Z-values histogram for motif Hoxc9

Sorted Z-values for motif Hoxc9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc9

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_129199919 3.538 ENSMUST00000029657.9
ENSMUST00000106382.4
 Pitx2

paired-like homeodomain transcription factor 2

chr3_+_129199878 2.758 ENSMUST00000174661.2
 Pitx2
paired-like homeodomain transcription factor 2
chr8_-_105471481 1.805 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr1_+_187997835 1.794 ENSMUST00000110938.1
 Esrrg
estrogen-related receptor gamma
chr1_+_187997821 1.741 ENSMUST00000027906.6
 Esrrg
estrogen-related receptor gamma
chr2_+_102658640 1.658 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_-_38714491 1.586 ENSMUST00000028084.4
 Nr5a1
nuclear receptor subfamily 5, group A, member 1
chr3_+_129199960 1.584 ENSMUST00000173645.2
 Pitx2
paired-like homeodomain transcription factor 2
chr4_+_136143497 1.476 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr10_-_92162753 1.356 ENSMUST00000182197.1
 Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr7_-_139582790 1.232 ENSMUST00000106095.2
 Nkx6-2
NK6 homeobox 2
chr2_+_70474923 1.054 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chr8_-_120228221 0.744 ENSMUST00000183235.1
 A330074K22Rik
RIKEN cDNA A330074K22 gene
chr10_+_4710119 0.742 ENSMUST00000105588.1
ENSMUST00000105589.1
 Esr1

estrogen receptor 1 (alpha)

chr3_+_66985647 0.687 ENSMUST00000162362.1
ENSMUST00000065074.7
 Rsrc1

arginine/serine-rich coiled-coil 1

chr16_-_37384915 0.655 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr3_+_66985700 0.618 ENSMUST00000046542.6
ENSMUST00000162693.1
 Rsrc1

arginine/serine-rich coiled-coil 1

chr13_-_25270076 0.586 ENSMUST00000057866.6
 Nrsn1
neurensin 1
chr1_-_45503282 0.535 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr13_-_78197815 0.511 ENSMUST00000127137.2
 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr16_-_37384940 0.503 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chrX_-_103186618 0.468 ENSMUST00000121720.1
 Nap1l2
nucleosome assembly protein 1-like 2
chr5_-_67427794 0.450 ENSMUST00000169190.1
 Bend4
BEN domain containing 4
chr2_-_26516620 0.408 ENSMUST00000132820.1
 Notch1
notch 1
chrX_+_56609843 0.374 ENSMUST00000077741.5
ENSMUST00000114784.2
 Slc9a6

solute carrier family 9 (sodium/hydrogen exchanger), member 6

chr19_+_24875679 0.358 ENSMUST00000073080.5
 Gm10053
predicted gene 10053
chr7_-_30612731 0.351 ENSMUST00000006476.4
 Upk1a
uroplakin 1A
chr11_-_72215592 0.320 ENSMUST00000021157.8
 Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chrX_+_56609751 0.307 ENSMUST00000144068.1
 Slc9a6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr5_-_44101668 0.263 ENSMUST00000087441.4
ENSMUST00000074113.6
 Prom1

prominin 1

chr3_+_66985680 0.252 ENSMUST00000065047.6
 Rsrc1
arginine/serine-rich coiled-coil 1
chr11_-_98022594 0.229 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
 Cacnb1



calcium channel, voltage-dependent, beta 1 subunit



chr18_-_56975333 0.214 ENSMUST00000139243.2
ENSMUST00000025488.8
 C330018D20Rik

RIKEN cDNA C330018D20 gene

chr17_+_24426676 0.209 ENSMUST00000024946.5
 Eci1
enoyl-Coenzyme A delta isomerase 1
chr3_+_67892189 0.193 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr5_+_67260696 0.171 ENSMUST00000161233.1
ENSMUST00000160352.1
 Tmem33

transmembrane protein 33

chr18_+_65582281 0.159 ENSMUST00000183319.1
 Zfp532
zinc finger protein 532
chr1_+_66321708 0.157 ENSMUST00000114013.1
 Map2
microtubule-associated protein 2
chr5_+_67260565 0.136 ENSMUST00000037918.5
ENSMUST00000162543.1
 Tmem33

transmembrane protein 33

chrX_-_18461371 0.131 ENSMUST00000044188.4
 4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr13_+_89540636 0.112 ENSMUST00000022108.7
 Hapln1
hyaluronan and proteoglycan link protein 1
chr12_-_15816762 0.108 ENSMUST00000020922.7
 Trib2
tribbles homolog 2 (Drosophila)
chr18_+_65582239 0.103 ENSMUST00000182684.1
 Zfp532
zinc finger protein 532
chr2_-_128967725 0.092 ENSMUST00000099385.2
 Gm10762
predicted gene 10762
chr10_-_88605017 0.074 ENSMUST00000119185.1
ENSMUST00000121629.1
 Mybpc1

myosin binding protein C, slow-type

chr11_-_94242701 0.073 ENSMUST00000061469.3
 Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr15_+_8968389 0.066 ENSMUST00000053308.9
ENSMUST00000166524.1
 Ranbp3l

RAN binding protein 3-like

chr17_-_57000018 0.062 ENSMUST00000002740.2
 Pspn
persephin
chr10_+_43524080 0.054 ENSMUST00000057649.6
 Gm9803
predicted gene 9803
chr9_-_89705017 0.054 ENSMUST00000058488.6
 Tmed3
transmembrane emp24 domain containing 3
chr18_+_65582390 0.020 ENSMUST00000169679.1
ENSMUST00000183326.1
 Zfp532

zinc finger protein 532

chr9_+_121710389 0.013 ENSMUST00000035113.9
 Deb1
differentially expressed in B16F10 1
chr10_-_67912620 0.012 ENSMUST00000064656.7
 Zfp365
zinc finger protein 365
chr1_-_74284636 0.007 ENSMUST00000178235.1
ENSMUST00000006462.7
 Aamp

angio-associated migratory protein

chr9_-_7835255 0.004 ENSMUST00000074246.6
 Birc2
baculoviral IAP repeat-containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.4 1.6 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.3 1.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 0.7 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.4 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.1 0.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 1.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662) cellular response to fatty acid(GO:0071398)
0.1 3.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0044308 axonal spine(GO:0044308)
0.1 0.3 GO:0071914 prominosome(GO:0071914)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.3 GO:0070847 core mediator complex(GO:0070847)
0.1 1.7 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 8.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.6 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 3.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 7.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.7 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0042805 actinin binding(GO:0042805)