Motif ID: Hsf4

Z-value: 0.612


Transcription factors associated with Hsf4:

Gene SymbolEntrez IDGene Name
Hsf4 ENSMUSG00000033249.4 Hsf4



Activity profile for motif Hsf4.

activity profile for motif Hsf4


Sorted Z-values histogram for motif Hsf4

Sorted Z-values for motif Hsf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_110696289 0.994 ENSMUST00000021698.6
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr9_+_71215779 0.973 ENSMUST00000034723.5
 Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr12_-_110696332 0.910 ENSMUST00000094361.4
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_+_150323702 0.900 ENSMUST00000133235.2
 Gm10130
predicted gene 10130
chr1_-_189688074 0.888 ENSMUST00000171929.1
ENSMUST00000165962.1
 Cenpf

centromere protein F

chr12_-_110696248 0.828 ENSMUST00000124156.1
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_-_110695860 0.791 ENSMUST00000149189.1
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr14_-_65833963 0.697 ENSMUST00000022613.9
 Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr15_-_58135047 0.607 ENSMUST00000038194.3
 Atad2
ATPase family, AAA domain containing 2
chr2_+_119897212 0.558 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
 Mga




MAX gene associated




chr17_+_17831004 0.551 ENSMUST00000172097.2
 4930546H06Rik
RIKEN cDNA 4930546H06 gene
chrX_+_42149288 0.535 ENSMUST00000115073.2
ENSMUST00000115072.1
 Stag2

stromal antigen 2

chr6_+_128438757 0.521 ENSMUST00000144745.1
 Gm10069
predicted gene 10069
chr4_-_136892867 0.519 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr19_-_50030735 0.501 ENSMUST00000071866.1
 Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr14_-_79390666 0.493 ENSMUST00000022597.7
 Naa16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr9_-_13826946 0.493 ENSMUST00000147115.1
 Cep57
centrosomal protein 57
chr11_-_90002881 0.487 ENSMUST00000020864.8
 Pctp
phosphatidylcholine transfer protein
chrX_-_109013389 0.478 ENSMUST00000033597.8
 Hmgn5
high-mobility group nucleosome binding domain 5
chr8_-_71537402 0.477 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.5 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 1.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3 1.0 GO:0035799 ureter maturation(GO:0035799)
0.1 1.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.9 GO:0021591 ventricular system development(GO:0021591)
0.1 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.7 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.6 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 0.5 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.1 0.5 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 0.5 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.1 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.5 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.5 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.3 GO:0072562 blood microparticle(GO:0072562)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.1 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 0.3 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.3 GO:0002135 CTP binding(GO:0002135)
0.1 1.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 1.0 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.8 GO:0045502 dynein binding(GO:0045502)
0.2 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 0.6 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.1 0.5 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.4 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.4 GO:0005118 sevenless binding(GO:0005118)