Motif ID: Ikzf2

Z-value: 0.795


Transcription factors associated with Ikzf2:

Gene SymbolEntrez IDGene Name
Ikzf2 ENSMUSG00000025997.7 Ikzf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf2mm10_v2_chr1_-_69685937_696859660.349.4e-02Click!


Activity profile for motif Ikzf2.

activity profile for motif Ikzf2


Sorted Z-values histogram for motif Ikzf2

Sorted Z-values for motif Ikzf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ikzf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 120 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 10.301 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chrX_+_103422010 7.952 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr19_+_55894508 3.474 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr15_+_3270767 2.562 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr7_-_70360593 1.954 ENSMUST00000032768.7
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr5_+_92897981 1.848 ENSMUST00000113051.2
 Shroom3
shroom family member 3
chr3_-_154330543 1.604 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr5_+_110330697 1.581 ENSMUST00000112481.1
 Pole
polymerase (DNA directed), epsilon
chrX_+_106920618 1.547 ENSMUST00000060576.7
 Lpar4
lysophosphatidic acid receptor 4
chr6_+_4003926 1.544 ENSMUST00000031670.8
 Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr11_-_84525514 1.417 ENSMUST00000018842.7
 Lhx1
LIM homeobox protein 1
chr4_+_57637816 1.375 ENSMUST00000150412.1
 Gm20459
predicted gene 20459
chr3_+_159839729 1.374 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chr8_-_61591130 1.327 ENSMUST00000135439.1
ENSMUST00000121200.1
 Palld

palladin, cytoskeletal associated protein

chr1_-_45503282 1.277 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr7_-_139582790 1.150 ENSMUST00000106095.2
 Nkx6-2
NK6 homeobox 2
chr8_-_80739497 1.106 ENSMUST00000043359.8
 Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr2_+_103970221 1.098 ENSMUST00000111140.2
ENSMUST00000111139.2
 Lmo2

LIM domain only 2

chr11_-_55419898 1.053 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr2_-_71546745 0.981 ENSMUST00000024159.6
 Dlx2
distal-less homeobox 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 10.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 3.5 GO:0048625 myoblast fate commitment(GO:0048625)
0.4 2.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 2.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.4 2.0 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 1.8 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.4 1.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 1.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 1.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.6 GO:0021884 forebrain neuron development(GO:0021884)
0.5 1.4 GO:0060067 cervix development(GO:0060067) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 1.4 GO:0031017 exocrine pancreas development(GO:0031017)
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 1.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.1 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.3 1.0 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.3 0.9 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.8 GO:0002102 podosome(GO:0002102)
0.0 1.8 GO:0043296 apical junction complex(GO:0043296)
0.3 1.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 1.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 1.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.1 GO:0016589 NURF complex(GO:0016589)
0.1 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 0.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 2.6 GO:0008430 selenium binding(GO:0008430)
0.0 2.2 GO:0051015 actin filament binding(GO:0051015)
0.2 2.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.9 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 1.5 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 1.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.8 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)