Motif ID: Irf4

Z-value: 0.595


Transcription factors associated with Irf4:

Gene SymbolEntrez IDGene Name
Irf4 ENSMUSG00000021356.3 Irf4



Activity profile for motif Irf4.

activity profile for motif Irf4


Sorted Z-values histogram for motif Irf4

Sorted Z-values for motif Irf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Irf4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_90537242 1.855 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr3_+_90537306 1.797 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chrX_-_134161928 1.297 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr11_-_77894096 1.158 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr1_-_163313661 1.134 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr19_-_58454580 1.101 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr19_-_58455161 0.915 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr19_-_58455398 0.788 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr14_-_122465677 0.776 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr6_+_82041623 0.750 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr11_+_119393060 0.743 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr3_-_142395661 0.660 ENSMUST00000029941.9
ENSMUST00000168967.2
ENSMUST00000090134.5
ENSMUST00000058626.8
Pdlim5



PDZ and LIM domain 5



chr2_-_127788854 0.646 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr7_+_58658181 0.629 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr11_-_101551837 0.621 ENSMUST00000017290.4
Brca1
breast cancer 1
chr19_-_24225015 0.601 ENSMUST00000099558.4
Tjp2
tight junction protein 2
chr6_+_71282280 0.573 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr5_+_28165690 0.569 ENSMUST00000036177.7
En2
engrailed 2
chr9_-_114564315 0.569 ENSMUST00000111816.2
Trim71
tripartite motif-containing 71
chr7_-_65370908 0.567 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr13_-_81570640 0.558 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr14_-_66124482 0.544 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr1_+_61638819 0.543 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr16_+_43235856 0.540 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr6_-_39118211 0.537 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr6_-_87335758 0.516 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr14_+_120275669 0.516 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr19_+_56397100 0.498 ENSMUST00000026062.9
Casp7
caspase 7
chr1_+_16688405 0.493 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr2_+_128126030 0.481 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr1_+_66468364 0.478 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chrX_+_150547375 0.451 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr6_+_128362919 0.443 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr13_-_113046357 0.434 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr4_+_115000156 0.422 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr10_+_128706251 0.398 ENSMUST00000054125.8
Pmel
premelanosome protein
chrX_+_94636066 0.396 ENSMUST00000096368.3
Gspt2
G1 to S phase transition 2
chr6_-_97060407 0.393 ENSMUST00000089295.4
Fam19a4
family with sequence similarity 19, member A4
chr4_-_89311021 0.386 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr13_-_100616911 0.379 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
Marveld2


MARVEL (membrane-associating) domain containing 2


chr4_+_115000174 0.371 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr1_-_14310198 0.362 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr16_-_5255923 0.344 ENSMUST00000139584.1
ENSMUST00000064635.5
Fam86

family with sequence similarity 86

chr12_-_110695860 0.344 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr9_-_116175318 0.330 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr2_-_51934644 0.328 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr7_-_141010759 0.328 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr15_-_50889691 0.327 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr13_+_5861489 0.326 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr16_-_43664145 0.324 ENSMUST00000096065.4
Tigit
T cell immunoreceptor with Ig and ITIM domains
chr10_+_94575257 0.321 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr10_-_41490335 0.318 ENSMUST00000019965.6
Smpd2
sphingomyelin phosphodiesterase 2, neutral
chr9_+_64811313 0.314 ENSMUST00000038890.5
Dennd4a
DENN/MADD domain containing 4A
chr2_-_9878580 0.308 ENSMUST00000102976.3
Gata3
GATA binding protein 3
chr16_-_26371828 0.287 ENSMUST00000023154.2
Cldn1
claudin 1
chr13_-_23710714 0.287 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr8_+_105170668 0.286 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr18_+_7869707 0.282 ENSMUST00000166062.1
ENSMUST00000169010.1
Wac

WW domain containing adaptor with coiled-coil

chr11_-_3539228 0.276 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
Smtn



smoothelin



chr1_-_57406443 0.274 ENSMUST00000160837.1
ENSMUST00000161780.1
Tyw5

tRNA-yW synthesizing protein 5

chr1_-_159168642 0.259 ENSMUST00000077309.1
Gm4953
predicted pseudogene 4953
chr9_+_85842852 0.258 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr4_-_136886187 0.251 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr14_+_60732906 0.248 ENSMUST00000162945.1
Spata13
spermatogenesis associated 13
chr3_+_95526777 0.246 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr9_+_45042425 0.246 ENSMUST00000034600.4
Mpzl2
myelin protein zero-like 2
chr2_+_71453276 0.246 ENSMUST00000037210.8
Metap1d
methionyl aminopeptidase type 1D (mitochondrial)
chr15_+_102977032 0.245 ENSMUST00000001706.6
Hoxc9
homeobox C9
chr1_-_174921813 0.242 ENSMUST00000055294.3
Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr17_-_30612613 0.235 ENSMUST00000167624.1
ENSMUST00000024823.6
Glo1

glyoxalase 1

chr13_-_107890059 0.229 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr7_-_80387935 0.229 ENSMUST00000080932.6
Fes
feline sarcoma oncogene
chr19_+_8850785 0.225 ENSMUST00000096257.2
Lrrn4cl
LRRN4 C-terminal like
chr17_+_34203527 0.223 ENSMUST00000025197.5
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_+_89421619 0.217 ENSMUST00000094378.3
ENSMUST00000137793.1
Shc1

src homology 2 domain-containing transforming protein C1

chrX_-_108834303 0.212 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr18_-_78142119 0.205 ENSMUST00000160639.1
Slc14a1
solute carrier family 14 (urea transporter), member 1
chr10_+_86022189 0.178 ENSMUST00000120344.1
ENSMUST00000117597.1
Fbxo7

F-box protein 7

chr12_+_52699297 0.173 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr1_+_187215737 0.172 ENSMUST00000160471.1
Gpatch2
G patch domain containing 2
chr10_+_18235030 0.169 ENSMUST00000181897.1
Gm10827
predicted gene 10827
chr8_+_128685654 0.167 ENSMUST00000090006.5
Itgb1
integrin beta 1 (fibronectin receptor beta)
chr17_+_35424870 0.158 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr16_+_24393350 0.150 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr5_-_104021919 0.147 ENSMUST00000031251.9
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr4_-_123139929 0.140 ENSMUST00000030404.4
Ppie
peptidylprolyl isomerase E (cyclophilin E)
chr1_+_58393119 0.133 ENSMUST00000050552.8
Bzw1
basic leucine zipper and W2 domains 1
chr19_+_33822908 0.130 ENSMUST00000042061.6
Gm5519
predicted pseudogene 5519
chrX_-_101222426 0.128 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr16_+_35938972 0.127 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chrX_+_94367112 0.127 ENSMUST00000113898.1
Apoo
apolipoprotein O
chr4_-_58911902 0.109 ENSMUST00000134848.1
ENSMUST00000107557.2
ENSMUST00000149301.1
AI314180


expressed sequence AI314180


chr11_+_62820469 0.109 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr1_+_132008285 0.107 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr1_-_161876656 0.104 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr13_+_96082158 0.104 ENSMUST00000185178.1
Gm17190
predicted gene 17190
chr5_-_104021799 0.098 ENSMUST00000119025.1
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr18_-_70530138 0.090 ENSMUST00000161542.1
ENSMUST00000159389.1
Poli

polymerase (DNA directed), iota

chr10_+_21882184 0.086 ENSMUST00000120509.1
Sgk1
serum/glucocorticoid regulated kinase 1
chrX_-_95444789 0.084 ENSMUST00000084535.5
Amer1
APC membrane recruitment 1
chr6_+_35177386 0.081 ENSMUST00000043815.9
Nup205
nucleoporin 205
chr10_-_100589205 0.080 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr13_+_24614608 0.079 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr11_+_78245743 0.078 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr18_-_70530313 0.077 ENSMUST00000043286.8
Poli
polymerase (DNA directed), iota
chr8_+_90828820 0.076 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr1_-_184732616 0.070 ENSMUST00000048572.6
Hlx
H2.0-like homeobox
chr4_-_72200833 0.069 ENSMUST00000102848.2
ENSMUST00000072695.6
ENSMUST00000107337.1
ENSMUST00000074216.7
Tle1



transducin-like enhancer of split 1, homolog of Drosophila E(spl)



chr6_-_49214954 0.068 ENSMUST00000031838.7
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr3_+_142496924 0.064 ENSMUST00000090127.2
Gbp5
guanylate binding protein 5
chr9_-_108428484 0.062 ENSMUST00000076592.2
Ccdc36
coiled-coil domain containing 36
chr7_-_16286744 0.061 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
Ccdc9


coiled-coil domain containing 9


chr9_+_35267857 0.056 ENSMUST00000034543.4
Rpusd4
RNA pseudouridylate synthase domain containing 4
chr7_+_4460687 0.055 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chrX_+_159303266 0.054 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr15_-_76243401 0.046 ENSMUST00000165738.1
ENSMUST00000075689.6
Parp10

poly (ADP-ribose) polymerase family, member 10

chr16_+_65520503 0.046 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chr4_-_46536096 0.042 ENSMUST00000102924.2
Trim14
tripartite motif-containing 14
chr7_-_62420139 0.039 ENSMUST00000094340.3
Mkrn3
makorin, ring finger protein, 3
chr17_+_34564268 0.039 ENSMUST00000015612.7
Notch4
notch 4
chr2_+_23069210 0.039 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr16_-_55838827 0.035 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr16_-_24393588 0.032 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr10_-_111997204 0.030 ENSMUST00000074805.5
Glipr1
GLI pathogenesis-related 1 (glioma)
chr13_+_42052015 0.028 ENSMUST00000060148.5
Hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr2_+_23069057 0.027 ENSMUST00000114526.1
ENSMUST00000114529.2
Acbd5

acyl-Coenzyme A binding domain containing 5

chr10_+_126978690 0.017 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_+_175632169 0.014 ENSMUST00000097458.3
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr7_+_83755904 0.011 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr10_+_69212634 0.009 ENSMUST00000020101.5
Rhobtb1
Rho-related BTB domain containing 1
chr2_+_147012996 0.008 ENSMUST00000028921.5
Xrn2
5'-3' exoribonuclease 2
chr11_+_69966896 0.005 ENSMUST00000151515.1
Cldn7
claudin 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0006553 lysine metabolic process(GO:0006553)
0.2 0.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.5 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.2 0.5 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.2 0.6 GO:1903011 negative regulation of bone development(GO:1903011)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.5 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0035799 ureter maturation(GO:0035799) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.8 GO:0033504 floor plate development(GO:0033504)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.3 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.1 0.3 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 1.1 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.3 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.3 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 0.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.4 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.6 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 3.7 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.0 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:1902915 negative regulation of protein import into nucleus, translocation(GO:0033159) protein poly-ADP-ribosylation(GO:0070212) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.3 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.3 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.3 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 0.4 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.1 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.1 0.2 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
0.1 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.3 GO:0002135 CTP binding(GO:0002135)
0.1 0.2 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.5 GO:0016594 glycine binding(GO:0016594)
0.0 2.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0043236 fibronectin binding(GO:0001968) laminin binding(GO:0043236)
0.0 0.2 GO:0046977 TAP binding(GO:0046977)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0045502 dynein binding(GO:0045502)
0.0 0.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)