Motif ID: Irx6_Irx2_Irx3

Z-value: 0.885

Transcription factors associated with Irx6_Irx2_Irx3:

Gene SymbolEntrez IDGene Name
Irx2 ENSMUSG00000001504.9 Irx2
Irx3 ENSMUSG00000031734.11 Irx3
Irx6 ENSMUSG00000031738.8 Irx6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Irx2mm10_v2_chr13_+_72628831_72628971-0.526.8e-03Click!
Irx6mm10_v2_chr8_+_92674289_92674289-0.491.1e-02Click!
Irx3mm10_v2_chr8_-_91801547_91801560-0.452.0e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Irx6_Irx2_Irx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45311538 5.451 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr2_-_67433181 3.029 ENSMUST00000180773.1
Gm26727
predicted gene, 26727
chr10_-_125328957 2.915 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr16_+_17146937 2.384 ENSMUST00000115706.1
ENSMUST00000069064.4
Ydjc

YdjC homolog (bacterial)

chr13_+_49504774 2.206 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr8_+_36489191 2.184 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr10_+_61171954 2.012 ENSMUST00000122261.1
ENSMUST00000121297.1
ENSMUST00000035894.5
Tbata


thymus, brain and testes associated


chr6_+_149130170 2.003 ENSMUST00000087348.3
Gm10203
predicted gene 10203
chr7_-_103827922 1.734 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr9_-_112232449 1.617 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr13_+_76579670 1.570 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr14_-_30353468 1.535 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr2_-_119271202 1.512 ENSMUST00000037360.7
Rhov
ras homolog gene family, member V
chr2_-_169405435 1.475 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr8_+_129118043 1.429 ENSMUST00000108744.1
1700008F21Rik
RIKEN cDNA 1700008F21 gene
chr2_-_98667264 1.312 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr3_-_87263518 1.257 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr7_+_19212521 1.254 ENSMUST00000060225.4
Gpr4
G protein-coupled receptor 4
chr6_-_48708206 1.142 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr5_-_137601043 1.118 ENSMUST00000037620.7
ENSMUST00000154708.1
Mospd3

motile sperm domain containing 3

chr2_-_79908428 1.036 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr2_-_52335134 0.967 ENSMUST00000075301.3
Neb
nebulin
chr4_-_139131058 0.963 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr4_-_76344227 0.944 ENSMUST00000050757.9
Ptprd
protein tyrosine phosphatase, receptor type, D
chr4_-_136898803 0.903 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr7_-_101845300 0.885 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chr1_+_159737510 0.883 ENSMUST00000111669.3
Tnr
tenascin R
chr6_-_131247342 0.837 ENSMUST00000032306.8
ENSMUST00000088867.6
Klra2

killer cell lectin-like receptor, subfamily A, member 2

chr9_-_120068263 0.827 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr5_-_43981757 0.791 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr18_+_35770318 0.787 ENSMUST00000165299.1
Gm16490
predicted gene 16490
chr12_-_81421910 0.770 ENSMUST00000085319.3
Adam4
a disintegrin and metallopeptidase domain 4
chr6_+_58833689 0.759 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr2_-_169587745 0.755 ENSMUST00000109160.2
Gm11011
predicted gene 11011
chr2_-_79908389 0.754 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr1_-_22315792 0.754 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr13_+_16014457 0.741 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr2_-_112480817 0.740 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr11_+_43474276 0.712 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2

C1q and tumor necrosis factor related protein 2

chr2_+_173000114 0.707 ENSMUST00000029013.3
ENSMUST00000132212.1
Rae1

RAE1 RNA export 1 homolog (S. pombe)

chr17_+_17316078 0.671 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr6_+_79818031 0.653 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr16_-_77602094 0.648 ENSMUST00000114231.1
Gm11146
predicted gene 11146
chr5_-_17849783 0.610 ENSMUST00000170051.1
ENSMUST00000165232.1
Cd36

CD36 antigen

chr4_+_154142363 0.604 ENSMUST00000030895.5
Wrap73
WD repeat containing, antisense to Trp73
chr12_+_17924294 0.599 ENSMUST00000169657.1
B430203G13Rik
RIKEN cDNA B430203G13 gene
chr5_+_37185897 0.583 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr2_+_131133497 0.580 ENSMUST00000110225.1
Gm11037
predicted gene 11037
chr19_-_57118981 0.565 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
Ablim1


actin-binding LIM protein 1


chr10_-_39122277 0.546 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr7_-_79386943 0.540 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr6_-_56901870 0.535 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr3_-_120886691 0.527 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr14_-_31001311 0.522 ENSMUST00000161219.1
ENSMUST00000182501.1
Spcs1

signal peptidase complex subunit 1 homolog (S. cerevisiae)

chr1_-_173942445 0.510 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr3_-_87263703 0.495 ENSMUST00000146512.1
Fcrls
Fc receptor-like S, scavenger receptor
chr8_+_84872105 0.493 ENSMUST00000136026.1
ENSMUST00000170296.1
Syce2

synaptonemal complex central element protein 2

chr1_-_52817643 0.485 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr11_-_46166397 0.485 ENSMUST00000020679.2
Nipal4
NIPA-like domain containing 4
chr13_-_34077992 0.480 ENSMUST00000056427.8
Tubb2a
tubulin, beta 2A class IIA
chr11_+_70029742 0.462 ENSMUST00000132597.2
Dlg4
discs, large homolog 4 (Drosophila)
chr10_-_29699379 0.458 ENSMUST00000092620.4
Gm10275
predicted pseudogene 10275
chr11_+_49794157 0.454 ENSMUST00000020629.4
Gfpt2
glutamine fructose-6-phosphate transaminase 2
chr2_+_133552159 0.447 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr7_-_4149781 0.441 ENSMUST00000058358.6
Leng9
leukocyte receptor cluster (LRC) member 9
chr13_-_27582168 0.430 ENSMUST00000006664.1
ENSMUST00000095926.1
Prl8a1

prolactin family 8, subfamily a, member 1

chr19_-_6908289 0.417 ENSMUST00000149261.1
Prdx5
peroxiredoxin 5
chr1_+_171840607 0.410 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr6_-_136941887 0.406 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr11_-_51635870 0.405 ENSMUST00000001081.3
Rmnd5b
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr3_-_59210881 0.404 ENSMUST00000040622.1
P2ry13
purinergic receptor P2Y, G-protein coupled 13
chr9_+_65346066 0.398 ENSMUST00000048184.2
Pdcd7
programmed cell death 7
chr2_+_150323702 0.397 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr5_+_61808843 0.392 ENSMUST00000053876.2
G6pd2
glucose-6-phosphate dehydrogenase 2
chr10_+_82378593 0.392 ENSMUST00000165906.1
Gm4924
predicted gene 4924
chr3_+_106113229 0.387 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr19_-_57118897 0.385 ENSMUST00000111526.1
Ablim1
actin-binding LIM protein 1
chr18_+_37447641 0.384 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr11_-_102897123 0.376 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr17_-_81649607 0.376 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr3_+_51559757 0.357 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr7_-_60005101 0.353 ENSMUST00000059305.10
Snrpn
small nuclear ribonucleoprotein N
chr12_+_55199533 0.340 ENSMUST00000177978.1
1700047I17Rik2
RIKEN cDNA 1700047I17 gene 2
chr15_-_35938186 0.336 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr12_+_55124528 0.330 ENSMUST00000177768.1
Fam177a
family with sequence similarity 177, member A
chr12_-_100159601 0.326 ENSMUST00000021596.7
Nrde2
nrde-2 necessary for RNA interference, domain containing
chr3_-_59262825 0.324 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr17_-_27133902 0.323 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr9_-_112217261 0.322 ENSMUST00000159451.1
ENSMUST00000162796.1
ENSMUST00000161097.1
Arpp21


cyclic AMP-regulated phosphoprotein, 21


chr2_-_86347764 0.317 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chrM_+_8600 0.316 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr11_+_118476824 0.309 ENSMUST00000135383.2
Engase
endo-beta-N-acetylglucosaminidase
chr6_-_88875035 0.306 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr10_-_127121125 0.301 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr6_-_136941694 0.294 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr8_+_34154563 0.294 ENSMUST00000033933.5
Tmem66
transmembrane protein 66
chr7_+_28350652 0.294 ENSMUST00000082134.4
Rps16
ribosomal protein S16
chr19_+_20601958 0.293 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr11_+_101155884 0.290 ENSMUST00000043654.9
Tubg2
tubulin, gamma 2
chr8_+_13037308 0.289 ENSMUST00000063820.5
ENSMUST00000033821.4
F10

coagulation factor X

chr12_+_104406704 0.286 ENSMUST00000021506.5
Serpina3n
serine (or cysteine) peptidase inhibitor, clade A, member 3N
chr7_+_27927592 0.284 ENSMUST00000181644.1
Gm26891
predicted gene, 26891
chr19_+_42247544 0.281 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr12_-_81379464 0.280 ENSMUST00000062182.7
Gm4787
predicted gene 4787
chr4_+_129335593 0.277 ENSMUST00000141235.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr7_-_112159034 0.268 ENSMUST00000033036.5
Dkk3
dickkopf homolog 3 (Xenopus laevis)
chr7_+_120842824 0.261 ENSMUST00000047875.8
Eef2k
eukaryotic elongation factor-2 kinase
chr16_-_4003750 0.261 ENSMUST00000171658.1
ENSMUST00000171762.1
Slx4

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

chr4_+_152199805 0.251 ENSMUST00000105652.2
Acot7
acyl-CoA thioesterase 7
chr4_-_36136463 0.250 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr14_+_53324632 0.250 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chrX_+_8271133 0.248 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr3_+_97628804 0.239 ENSMUST00000107050.1
ENSMUST00000029729.8
ENSMUST00000107049.1
Fmo5


flavin containing monooxygenase 5


chr14_-_5863663 0.230 ENSMUST00000178594.1
Gm8237
predicted gene 8237
chr14_+_57798182 0.226 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr3_-_88951146 0.226 ENSMUST00000173135.1
Dap3
death associated protein 3
chr9_+_92309362 0.225 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr1_-_147281942 0.223 ENSMUST00000066758.2
Gm9931
predicted gene 9931
chr10_+_39732099 0.222 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr10_-_99126321 0.221 ENSMUST00000060761.5
Phxr2
per-hexamer repeat gene 2
chr1_-_137969213 0.220 ENSMUST00000182680.1
ENSMUST00000182424.1
Gm26936

predicted gene, 26936

chr3_-_34351685 0.218 ENSMUST00000174114.1
Gm20514
predicted gene 20514
chr16_+_77846693 0.217 ENSMUST00000169531.1
Gm17333
predicted gene, 17333
chr13_+_63282142 0.216 ENSMUST00000159152.1
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr19_-_28967794 0.215 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr2_-_30967859 0.215 ENSMUST00000028200.8
Tor1a
torsin family 1, member A (torsin A)
chr14_+_123659971 0.215 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr5_-_140702241 0.211 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
Iqce


IQ motif containing E


chr6_-_47830867 0.211 ENSMUST00000058844.5
Zfp786
zinc finger protein 786
chr11_+_98026918 0.209 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr14_+_3667518 0.209 ENSMUST00000112801.3
Gm3020
predicted gene 3020
chr7_-_80324115 0.208 ENSMUST00000123189.1
Rccd1
RCC1 domain containing 1
chr3_-_150073620 0.207 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr13_+_23738804 0.204 ENSMUST00000040914.1
Hist1h1c
histone cluster 1, H1c
chr9_+_64173364 0.202 ENSMUST00000034966.7
Rpl4
ribosomal protein L4
chr4_+_119195496 0.200 ENSMUST00000097908.3
Ccdc23
coiled-coil domain containing 23
chr1_-_180996145 0.200 ENSMUST00000154133.1
Ephx1
epoxide hydrolase 1, microsomal
chr5_+_135168283 0.199 ENSMUST00000031692.5
Bcl7b
B cell CLL/lymphoma 7B
chr3_+_106034661 0.194 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr7_-_80324418 0.192 ENSMUST00000047362.4
ENSMUST00000121882.1
Rccd1

RCC1 domain containing 1

chr10_-_58718210 0.190 ENSMUST00000169859.1
Gm17542
predicted gene, 17542
chr14_+_5517172 0.190 ENSMUST00000178220.1
Gm3488
predicted gene, 3488
chr14_+_5164535 0.190 ENSMUST00000179659.1
Gm3317
predicted gene 3317
chr4_-_47057296 0.190 ENSMUST00000107747.1
ENSMUST00000084616.2
Anks6

ankyrin repeat and sterile alpha motif domain containing 6

chr19_+_8892987 0.189 ENSMUST00000096249.5
Ints5
integrator complex subunit 5
chr5_+_115279666 0.187 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr2_-_168734236 0.187 ENSMUST00000109175.2
Atp9a
ATPase, class II, type 9A
chr11_+_98026695 0.186 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr6_+_86078070 0.185 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr15_-_83149307 0.180 ENSMUST00000100375.4
Poldip3
polymerase (DNA-directed), delta interacting protein 3
chr9_-_108428484 0.180 ENSMUST00000076592.2
Ccdc36
coiled-coil domain containing 36
chr11_-_70646889 0.178 ENSMUST00000136383.1
Slc25a11
solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
chr4_+_119195353 0.177 ENSMUST00000106345.2
Ccdc23
coiled-coil domain containing 23
chr3_-_9004472 0.177 ENSMUST00000091355.5
ENSMUST00000134788.1
Tpd52

tumor protein D52

chr4_-_20778852 0.176 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr13_-_104863883 0.176 ENSMUST00000043061.4
Fam159b
family with sequence similarity 159, member B
chr8_-_54724317 0.172 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr7_-_44744230 0.171 ENSMUST00000149011.1
Zfp473
zinc finger protein 473
chr19_-_6128208 0.170 ENSMUST00000025702.7
Snx15
sorting nexin 15
chr8_-_54724474 0.170 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr6_-_85820936 0.170 ENSMUST00000174143.1
Gm11128
predicted gene 11128
chr13_+_49544443 0.168 ENSMUST00000177948.1
ENSMUST00000021820.6
Aspn

asporin

chr12_+_108410542 0.167 ENSMUST00000054955.7
Eml1
echinoderm microtubule associated protein like 1
chr2_+_84826997 0.164 ENSMUST00000028470.3
Timm10
translocase of inner mitochondrial membrane 10
chr18_+_51117754 0.164 ENSMUST00000116639.2
Prr16
proline rich 16
chr6_+_125039760 0.162 ENSMUST00000140131.1
ENSMUST00000032480.7
Ing4

inhibitor of growth family, member 4

chr17_-_24455265 0.162 ENSMUST00000056032.7
E4f1
E4F transcription factor 1
chr4_-_116075022 0.161 ENSMUST00000050580.4
ENSMUST00000078676.5
Uqcrh

ubiquinol-cytochrome c reductase hinge protein

chr10_+_95792571 0.159 ENSMUST00000084674.4
4732465J04Rik
RIKEN cDNA 4732465J04 gene
chr18_+_37518341 0.159 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr8_+_71469186 0.158 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
Dda1


DET1 and DDB1 associated 1


chr4_+_116075269 0.156 ENSMUST00000030471.8
Lrrc41
leucine rich repeat containing 41
chr15_-_3979432 0.154 ENSMUST00000022791.8
Fbxo4
F-box protein 4
chr14_+_4514758 0.153 ENSMUST00000112776.2
Gm3173
predicted gene 3173
chr15_+_44196135 0.153 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr12_-_102423741 0.153 ENSMUST00000110020.1
Lgmn
legumain
chr17_-_57839233 0.152 ENSMUST00000095218.3
Rpl7a-ps5
ribosomal protein L7A, pseudogene 5
chr6_+_86371489 0.152 ENSMUST00000089558.5
Snrpg
small nuclear ribonucleoprotein polypeptide G
chr16_-_52296924 0.151 ENSMUST00000167115.1
Alcam
activated leukocyte cell adhesion molecule
chr13_+_78024892 0.149 ENSMUST00000175955.2
Pou5f2
POU domain class 5, transcription factor 2
chr3_-_106167564 0.146 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr7_-_60005049 0.146 ENSMUST00000179360.1
Snurf
SNRPN upstream reading frame
chr9_-_58202281 0.146 ENSMUST00000163897.1
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr2_+_131909928 0.144 ENSMUST00000091288.6
Prnp
prion protein
chr19_-_32466575 0.143 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr15_+_102503722 0.143 ENSMUST00000096145.4
Gm10337
predicted gene 10337
chr14_-_121915774 0.141 ENSMUST00000055475.7
Gpr18
G protein-coupled receptor 18
chr7_+_127573376 0.139 ENSMUST00000033086.1
Phkg2
phosphorylase kinase, gamma 2 (testis)
chr15_-_35938009 0.138 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr11_+_100320596 0.138 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr11_+_48837465 0.138 ENSMUST00000046903.5
Trim7
tripartite motif-containing 7
chr7_+_102210335 0.137 ENSMUST00000140631.1
ENSMUST00000120879.1
ENSMUST00000146996.1
Pgap2


post-GPI attachment to proteins 2


chr12_+_108410625 0.137 ENSMUST00000109857.1
Eml1
echinoderm microtubule associated protein like 1
chr4_-_133872997 0.136 ENSMUST00000137486.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr17_+_28691342 0.136 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
Mapk14



mitogen-activated protein kinase 14



chr14_+_50870355 0.136 ENSMUST00000181697.1
ENSMUST00000181482.1
Gm26782

predicted gene, 26782

chrM_+_7759 0.131 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr1_+_194938821 0.131 ENSMUST00000016638.2
ENSMUST00000110815.2
Cd34

CD34 antigen

chr14_+_4430992 0.130 ENSMUST00000164603.1
ENSMUST00000166848.1
Gm3173

predicted gene 3173

chr17_-_80290476 0.128 ENSMUST00000086555.3
ENSMUST00000038166.7
Dhx57

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.7 2.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.5 1.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.4 1.3 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.3 0.9 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 0.8 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
0.2 0.6 GO:0070543 response to linoleic acid(GO:0070543)
0.2 0.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.4 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.1 0.7 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.4 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.1 0.4 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.9 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 1.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.1 0.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.1 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.3 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) regulation of cortisol biosynthetic process(GO:2000064) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1 0.3 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 2.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.6 GO:0045047 protein targeting to ER(GO:0045047)
0.0 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) cellular response to copper ion(GO:0071280)
0.0 0.7 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.1 GO:0006507 GPI anchor release(GO:0006507)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:2000507 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464) positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.4 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.5 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 1.0 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0010511 serotonin receptor signaling pathway(GO:0007210) regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.0 GO:0043379 memory T cell differentiation(GO:0043379)
0.0 2.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 2.3 GO:0008033 tRNA processing(GO:0008033)
0.0 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.7 GO:0048515 spermatid differentiation(GO:0048515)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0043374 gamma-delta T cell differentiation(GO:0042492) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 5.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 0.9 GO:0072534 perineuronal net(GO:0072534)
0.2 0.7 GO:0043512 inhibin A complex(GO:0043512)
0.2 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.2 0.5 GO:0000801 central element(GO:0000801)
0.2 1.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.3 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0046930 pore complex(GO:0046930)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0070052 collagen V binding(GO:0070052)
0.7 2.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.4 1.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.4 5.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 0.9 GO:0051870 methotrexate binding(GO:0051870)
0.3 1.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.3 1.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.8 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.4 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 2.4 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.1 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 0.5 GO:0019841 retinol binding(GO:0019841)
0.1 0.3 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.9 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.3 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 2.3 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0023026 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)