Motif ID: Jun

Z-value: 0.464


Transcription factors associated with Jun:

Gene SymbolEntrez IDGene Name
Jun ENSMUSG00000052684.3 Jun

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Junmm10_v2_chr4_-_95052188_950522220.442.3e-02Click!


Activity profile for motif Jun.

activity profile for motif Jun


Sorted Z-values histogram for motif Jun

Sorted Z-values for motif Jun



Network of associatons between targets according to the STRING database.



First level regulatory network of Jun

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_25395866 1.835 ENSMUST00000028328.2
Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr14_+_65968483 1.755 ENSMUST00000022616.6
Clu
clusterin
chr10_-_76725978 0.956 ENSMUST00000001147.4
Col6a1
collagen, type VI, alpha 1
chr6_+_17463927 0.922 ENSMUST00000115442.1
Met
met proto-oncogene
chr3_-_88503187 0.885 ENSMUST00000120377.1
Lmna
lamin A
chr7_+_139834148 0.766 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr7_+_4460687 0.750 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr7_+_110772604 0.736 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr3_-_88503331 0.703 ENSMUST00000029699.6
Lmna
lamin A
chr13_-_113663670 0.664 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr2_+_164948219 0.618 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr5_-_92348871 0.614 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr6_+_17463749 0.612 ENSMUST00000115443.1
Met
met proto-oncogene
chr18_+_61045139 0.609 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr7_-_105482197 0.579 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr1_-_22805994 0.578 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr2_-_77703252 0.555 ENSMUST00000171063.1
Zfp385b
zinc finger protein 385B
chr2_-_129371131 0.543 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr2_+_71117923 0.513 ENSMUST00000028403.2
Cybrd1
cytochrome b reductase 1
chr7_-_100964371 0.494 ENSMUST00000060174.4
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3 1.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.2 1.8 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.4 1.6 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 1.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.7 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.7 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.2 0.6 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.2 0.6 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.2 0.6 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.1 0.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122)
0.1 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.6 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.2 0.5 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.2 0.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.5 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.5 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.9 GO:0009925 basal plasma membrane(GO:0009925)
0.3 1.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.2 1.6 GO:0005638 lamin filament(GO:0005638)
0.1 1.5 GO:0005605 basal lamina(GO:0005605)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.1 0.7 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.8 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 1.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.0 GO:0042805 actinin binding(GO:0042805)
0.1 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 0.4 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)