Motif ID: Klf15

Z-value: 1.407


Transcription factors associated with Klf15:

Gene SymbolEntrez IDGene Name
Klf15 ENSMUSG00000030087.5 Klf15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf15mm10_v2_chr6_+_90465287_904653040.681.2e-04Click!


Activity profile for motif Klf15.

activity profile for motif Klf15


Sorted Z-values histogram for motif Klf15

Sorted Z-values for motif Klf15



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_56971762 9.650 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr18_-_66291770 6.309 ENSMUST00000130300.1
 Ccbe1
collagen and calcium binding EGF domains 1
chr1_-_56972437 5.479 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr17_+_46297917 5.234 ENSMUST00000166617.1
ENSMUST00000170271.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr18_-_89769479 5.172 ENSMUST00000097495.3
 Dok6
docking protein 6
chr3_+_117575268 4.389 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr6_-_148444336 4.347 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr2_-_5714490 3.993 ENSMUST00000044009.7
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr11_+_98348404 3.787 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_+_24076529 3.733 ENSMUST00000148087.1
 Gm12063
predicted gene 12063
chr7_+_46396439 3.223 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr1_-_72536930 3.212 ENSMUST00000047786.5
 March4
membrane-associated ring finger (C3HC4) 4
chr5_+_130448801 3.179 ENSMUST00000111288.2
 Caln1
calneuron 1
chr11_+_50602072 3.155 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr11_-_54068932 2.983 ENSMUST00000093109.4
ENSMUST00000018755.3
 Pdlim4

PDZ and LIM domain 4

chr11_+_69765970 2.979 ENSMUST00000108642.1
ENSMUST00000156932.1
 Zbtb4

zinc finger and BTB domain containing 4

chr11_+_69765899 2.948 ENSMUST00000108640.1
ENSMUST00000108639.1
 Zbtb4

zinc finger and BTB domain containing 4

chr14_-_39472825 2.816 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
 Nrg3


neuregulin 3


chr5_-_100159261 2.632 ENSMUST00000139520.1
 Tmem150c
transmembrane protein 150C
chr3_+_117575227 2.586 ENSMUST00000106473.2
 4833424O15Rik
RIKEN cDNA 4833424O15 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 138 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 15.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.6 6.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
1.0 6.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 5.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 4.6 GO:0006491 N-glycan processing(GO:0006491)
0.6 4.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 3.9 GO:0060074 synapse maturation(GO:0060074)
1.3 3.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 3.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 3.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.9 3.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 3.2 GO:0030574 collagen catabolic process(GO:0030574)
0.1 3.2 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.2 2.9 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.9 2.8 GO:0060596 mammary placode formation(GO:0060596)
0.9 2.8 GO:0071544 diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.5 2.7 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.4 2.7 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 2.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.5 2.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 8.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 5.3 GO:0097440 apical dendrite(GO:0097440)
0.1 5.0 GO:0032590 dendrite membrane(GO:0032590)
0.1 4.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
1.3 4.0 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.0 4.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.8 GO:0005795 Golgi stack(GO:0005795)
0.0 3.8 GO:0030175 filopodium(GO:0030175)
0.1 3.6 GO:0042734 presynaptic membrane(GO:0042734)
0.1 3.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 2.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.4 2.3 GO:0008091 spectrin(GO:0008091)
0.1 2.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.1 GO:0045335 phagocytic vesicle(GO:0045335)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.2 GO:0070412 R-SMAD binding(GO:0070412)
0.2 7.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 6.3 GO:0005518 collagen binding(GO:0005518)
0.2 6.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 5.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 5.2 GO:0005158 insulin receptor binding(GO:0005158)
0.5 4.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 4.2 GO:0008083 growth factor activity(GO:0008083)
1.3 3.8 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.3 3.5 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.0 3.3 GO:0017124 SH3 domain binding(GO:0017124)
0.1 3.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 2.8 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.3 2.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 2.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 2.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 2.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.2 GO:0003714 transcription corepressor activity(GO:0003714)