Motif ID: Klf3

Z-value: 0.285


Transcription factors associated with Klf3:

Gene SymbolEntrez IDGene Name
Klf3 ENSMUSG00000029178.8 Klf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf3mm10_v2_chr5_+_64812336_64812350-0.242.4e-01Click!


Activity profile for motif Klf3.

activity profile for motif Klf3


Sorted Z-values histogram for motif Klf3

Sorted Z-values for motif Klf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103827922 0.494 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr12_+_87026286 0.489 ENSMUST00000146292.1
Tmem63c
transmembrane protein 63c
chr12_+_87026564 0.488 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr15_-_102722150 0.477 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr15_-_102722120 0.425 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr7_+_82337218 0.375 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr7_-_4149781 0.316 ENSMUST00000058358.6
Leng9
leukocyte receptor cluster (LRC) member 9
chr3_-_89089955 0.294 ENSMUST00000166687.1
Rusc1
RUN and SH3 domain containing 1
chr1_+_135147615 0.263 ENSMUST00000125774.1
Arl8a
ADP-ribosylation factor-like 8A
chr1_+_107511489 0.262 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_107511416 0.243 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr15_+_76457438 0.232 ENSMUST00000043089.7
Scx
scleraxis
chr3_+_90080442 0.136 ENSMUST00000127955.1
Tpm3
tropomyosin 3, gamma
chr19_+_10041548 0.129 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chrX_+_7884321 0.104 ENSMUST00000096514.3
ENSMUST00000123277.1
Slc35a2

solute carrier family 35 (UDP-galactose transporter), member A2

chr1_+_72824482 0.102 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr11_-_97500340 0.088 ENSMUST00000056955.1
4933428G20Rik
RIKEN cDNA 4933428G20 gene
chr9_+_109931863 0.069 ENSMUST00000165876.1
Map4
microtubule-associated protein 4
chr4_-_41774097 0.069 ENSMUST00000108036.1
ENSMUST00000173865.1
ENSMUST00000108037.2
ENSMUST00000108032.2
Ccl27a



chemokine (C-C motif) ligand 27A



chr1_+_131867224 0.053 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr11_+_68968107 0.050 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chrX_-_74246534 0.043 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr3_+_89266552 0.038 ENSMUST00000040824.1
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr7_-_17027853 0.019 ENSMUST00000003183.5
Ppp5c
protein phosphatase 5, catalytic subunit
chr3_+_90079540 0.018 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
Tpm3


tropomyosin 3, gamma


chr7_-_17027807 0.008 ENSMUST00000142597.1
Ppp5c
protein phosphatase 5, catalytic subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.0 1.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)