Motif ID: Klf6_Patz1

Z-value: 1.492

Transcription factors associated with Klf6_Patz1:

Gene SymbolEntrez IDGene Name
Klf6 ENSMUSG00000000078.6 Klf6
Patz1 ENSMUSG00000020453.11 Patz1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Patz1mm10_v2_chr11_+_3289168_3289281-0.311.2e-01Click!
Klf6mm10_v2_chr13_+_5861489_5861501-0.144.8e-01Click!


Activity profile for motif Klf6_Patz1.

activity profile for motif Klf6_Patz1


Sorted Z-values histogram for motif Klf6_Patz1

Sorted Z-values for motif Klf6_Patz1



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf6_Patz1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102296618 8.654 ENSMUST00000107132.2
ENSMUST00000073234.2
 Atxn7l3

ataxin 7-like 3

chr5_+_37028329 5.818 ENSMUST00000173836.1
 Jakmip1
janus kinase and microtubule interacting protein 1
chr7_+_44310213 5.382 ENSMUST00000107938.1
 Shank1
SH3/ankyrin domain gene 1
chr11_-_95514570 4.537 ENSMUST00000058866.7
 Nxph3
neurexophilin 3
chr6_-_85502858 3.583 ENSMUST00000161546.1
ENSMUST00000161078.1
 Fbxo41

F-box protein 41

chr11_-_6065538 3.549 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr6_-_85502980 3.389 ENSMUST00000159062.1
 Fbxo41
F-box protein 41
chr19_+_6418731 3.336 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
 Nrxn2


neurexin II


chr2_-_24763047 3.298 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
 Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr12_+_12262139 3.225 ENSMUST00000069066.6
ENSMUST00000069005.8
 Fam49a

family with sequence similarity 49, member A

chr18_+_37955544 3.200 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
 Rell2




RELT-like 2




chr11_+_67455339 3.074 ENSMUST00000108681.1
 Gas7
growth arrest specific 7
chr14_-_39472825 2.983 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
 Nrg3


neuregulin 3


chr19_+_6497772 2.937 ENSMUST00000113458.1
ENSMUST00000113459.1
 Nrxn2

neurexin II

chr11_+_119942763 2.878 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
 Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2




chr5_-_138279960 2.865 ENSMUST00000014089.7
ENSMUST00000161827.1
 Gpc2

glypican 2 (cerebroglycan)

chr4_-_120287349 2.768 ENSMUST00000102656.3
 Foxo6
forkhead box O6
chr17_+_86167777 2.719 ENSMUST00000097275.2
 Prkce
protein kinase C, epsilon
chr9_-_106656081 2.699 ENSMUST00000023959.7
 Grm2
glutamate receptor, metabotropic 2
chr18_-_24709348 2.691 ENSMUST00000067987.1
 Gm9955
predicted gene 9955

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 640 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 18.0 GO:0071625 vocalization behavior(GO:0071625)
0.3 8.7 GO:0060074 synapse maturation(GO:0060074)
0.5 7.9 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.3 7.8 GO:0016578 histone deubiquitination(GO:0016578)
0.5 7.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 7.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 6.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.2 6.4 GO:0007520 myoblast fusion(GO:0007520)
0.3 6.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 5.6 GO:0071242 cellular response to ammonium ion(GO:0071242)
1.8 5.4 GO:0046959 habituation(GO:0046959)
0.4 5.3 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.2 4.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
1.5 4.6 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.7 4.3 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1 4.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.4 4.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.4 4.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 4.2 GO:0071806 intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
0.3 4.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 216 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 21.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 20.5 GO:0070382 exocytic vesicle(GO:0070382)
0.3 17.8 GO:0042734 presynaptic membrane(GO:0042734)
0.2 16.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 13.0 GO:0043025 neuronal cell body(GO:0043025)
0.1 10.0 GO:0055037 recycling endosome(GO:0055037)
0.3 9.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 9.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.4 9.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 9.1 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 8.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.5 7.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.6 7.2 GO:0000124 SAGA complex(GO:0000124)
0.2 7.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 6.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.7 6.8 GO:0044327 dendritic spine head(GO:0044327)
0.7 6.6 GO:0045298 tubulin complex(GO:0045298)
0.1 6.6 GO:0030027 lamellipodium(GO:0030027)
0.1 5.5 GO:0031225 anchored component of membrane(GO:0031225)
0.4 5.4 GO:0030122 AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 362 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.4 9.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 9.0 GO:0017124 SH3 domain binding(GO:0017124)
0.1 8.9 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 8.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.6 8.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 7.3 GO:0050811 GABA receptor binding(GO:0050811)
0.3 7.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 7.2 GO:0005246 calcium channel regulator activity(GO:0005246)
1.8 7.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.9 6.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 6.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 6.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 6.0 GO:0005518 collagen binding(GO:0005518)
0.1 5.9 GO:0045499 chemorepellent activity(GO:0045499)
0.3 5.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 5.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 5.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.6 4.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 4.5 GO:0043274 phospholipase binding(GO:0043274)