Motif ID: Klf7

Z-value: 0.457


Transcription factors associated with Klf7:

Gene SymbolEntrez IDGene Name
Klf7 ENSMUSG00000025959.7 Klf7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf7mm10_v2_chr1_-_64122256_64122321-0.086.9e-01Click!


Activity profile for motif Klf7.

activity profile for motif Klf7


Sorted Z-values histogram for motif Klf7

Sorted Z-values for motif Klf7



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf7

PNG image of the network

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Top targets:


Showing 1 to 20 of 91 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_897782 2.473 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr2_-_156312470 1.433 ENSMUST00000079125.6
Scand1
SCAN domain-containing 1
chr12_+_49382791 1.135 ENSMUST00000179669.1
Foxg1
forkhead box G1
chr12_+_49383007 1.067 ENSMUST00000021333.3
Foxg1
forkhead box G1
chr3_+_28263205 0.851 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr6_-_88875035 0.824 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr15_+_30172570 0.732 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr5_+_137761680 0.725 ENSMUST00000110983.2
ENSMUST00000031738.4
Tsc22d4

TSC22 domain family, member 4

chr4_+_107830958 0.718 ENSMUST00000106731.2
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr15_-_102722150 0.628 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr5_+_137778849 0.625 ENSMUST00000126126.1
ENSMUST00000031739.4
Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr15_-_102722120 0.608 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr7_-_28766469 0.577 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr4_+_139622842 0.566 ENSMUST00000039818.9
Aldh4a1
aldehyde dehydrogenase 4 family, member A1
chr2_+_172550991 0.566 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr6_-_88874597 0.562 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2


podocalyxin-like 2


chr18_+_67133713 0.479 ENSMUST00000076605.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr5_-_137741601 0.438 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr7_-_74013676 0.429 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr7_-_68749170 0.414 ENSMUST00000118110.1
ENSMUST00000048068.7
Arrdc4

arrestin domain containing 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.7 2.2 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 1.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.7 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.7 GO:0006970 response to osmotic stress(GO:0006970)
0.2 0.6 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.2 0.6 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 0.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537) proline biosynthetic process(GO:0006561)
0.0 0.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.4 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.4 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.4 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.3 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.3 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.2 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 0.7 GO:0038025 reelin receptor activity(GO:0038025)
0.2 0.7 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.6 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 0.5 GO:0050827 toxin receptor binding(GO:0050827)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0019172 glyoxalase III activity(GO:0019172)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)