Motif ID: Lef1

Z-value: 1.964


Transcription factors associated with Lef1:

Gene SymbolEntrez IDGene Name
Lef1 ENSMUSG00000027985.8 Lef1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lef1mm10_v2_chr3_+_131110350_1311104710.699.0e-05Click!


Activity profile for motif Lef1.

activity profile for motif Lef1


Sorted Z-values histogram for motif Lef1

Sorted Z-values for motif Lef1



Network of associatons between targets according to the STRING database.



First level regulatory network of Lef1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_98169542 16.441 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr7_-_144939823 11.816 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr14_-_48662740 11.579 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr17_-_70851189 10.312 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr7_-_49636847 9.765 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr10_-_92165159 9.065 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr19_+_55742242 7.742 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr5_+_75075464 7.613 ENSMUST00000160104.1
ENSMUST00000040477.3
Gsx2

GS homeobox 2

chr12_-_119238794 7.460 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr2_+_70474923 6.625 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr3_-_57575760 6.612 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr12_+_103314944 6.288 ENSMUST00000179363.1
Fam181a
family with sequence similarity 181, member A
chr11_+_108920800 6.266 ENSMUST00000140821.1
Axin2
axin2
chr8_+_108714644 6.224 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr3_+_102010138 6.216 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr8_-_46294592 6.184 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr6_-_148944750 6.132 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr3_-_57575907 5.885 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr19_+_55741884 5.775 ENSMUST00000111658.3
ENSMUST00000111654.1
Tcf7l2

transcription factor 7 like 2, T cell specific, HMG box

chr19_+_55742056 5.749 ENSMUST00000111659.2
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr12_+_52516077 5.703 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr10_-_92164666 5.544 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr3_+_131110350 5.436 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr7_-_115824699 5.361 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr11_+_88068242 5.243 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr1_-_138842429 5.232 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr2_+_30078584 5.196 ENSMUST00000045246.7
Pkn3
protein kinase N3
chr18_+_82914632 5.175 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr1_+_6734827 5.053 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr2_-_26092149 4.975 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr12_-_54986363 4.896 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr1_-_165934900 4.782 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr18_+_11633276 4.740 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr14_+_27039001 4.718 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr19_+_55895508 4.706 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr19_+_55741810 4.488 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr2_-_180889660 4.465 ENSMUST00000137629.1
Gm14342
predicted gene 14342
chr4_-_21685782 4.359 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr4_+_8691303 4.273 ENSMUST00000051558.3
Chd7
chromodomain helicase DNA binding protein 7
chr11_+_108920342 4.247 ENSMUST00000052915.7
Axin2
axin2
chr4_-_34882919 4.235 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr15_+_34238026 4.214 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr7_+_45216671 4.176 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr12_-_54986328 4.169 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr19_-_59170978 4.144 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr4_-_63403330 4.111 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr6_-_72788952 3.942 ENSMUST00000114053.2
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr3_-_116424007 3.938 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr7_-_70366735 3.890 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr5_+_110330697 3.871 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr6_-_72789240 3.865 ENSMUST00000069536.5
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr6_-_138426735 3.839 ENSMUST00000162932.1
Lmo3
LIM domain only 3
chrX_-_48034842 3.832 ENSMUST00000039026.7
Apln
apelin
chr18_+_82910863 3.808 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr4_-_97584605 3.778 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_-_37772868 3.746 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr1_+_187997835 3.742 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr1_+_187997821 3.687 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr14_-_48667508 3.631 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr6_+_15185456 3.597 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr4_+_62965560 3.586 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr3_-_116423930 3.566 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr7_-_37773555 3.562 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr1_+_135232045 3.521 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr11_+_117332335 3.489 ENSMUST00000106349.1
Sept9
septin 9
chr10_-_5805412 3.468 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr4_-_97584612 3.426 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr18_+_34625009 3.416 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr9_+_119402444 3.400 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr7_-_103843154 3.378 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr11_+_108921648 3.349 ENSMUST00000144511.1
Axin2
axin2
chr3_-_154330543 3.305 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr8_+_44950208 3.302 ENSMUST00000098796.3
Fat1
FAT tumor suppressor homolog 1 (Drosophila)
chrX_+_109095359 3.292 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr1_-_163313661 3.230 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr4_-_58499398 3.175 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr12_-_73113407 3.163 ENSMUST00000175693.1
Six4
sine oculis-related homeobox 4
chr12_+_76072016 3.147 ENSMUST00000131480.1
Syne2
spectrin repeat containing, nuclear envelope 2
chr5_+_77266196 3.147 ENSMUST00000113449.1
Rest
RE1-silencing transcription factor
chr5_+_47984571 3.135 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr5_+_47984793 3.082 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
Slit2



slit homolog 2 (Drosophila)



chr9_+_91368970 3.040 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr5_+_77265454 3.039 ENSMUST00000080359.5
Rest
RE1-silencing transcription factor
chr2_+_15055274 3.031 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr10_-_21160925 2.981 ENSMUST00000020158.6
Myb
myeloblastosis oncogene
chr6_+_53573364 2.971 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr6_+_83137089 2.970 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr6_-_124813065 2.936 ENSMUST00000149610.2
Tpi1
triosephosphate isomerase 1
chr12_-_16800674 2.928 ENSMUST00000162112.1
Greb1
gene regulated by estrogen in breast cancer protein
chr7_-_116038734 2.922 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr18_-_62756275 2.886 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr15_-_50889691 2.874 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr10_+_94036001 2.855 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr13_+_35741313 2.826 ENSMUST00000163595.2
Cdyl
chromodomain protein, Y chromosome-like
chr11_-_102925086 2.823 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr18_+_34624621 2.819 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr19_-_37330613 2.779 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr2_-_101883010 2.773 ENSMUST00000154525.1
Prr5l
proline rich 5 like
chr4_-_97778042 2.750 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_+_108479081 2.748 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr9_+_91368811 2.670 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr17_+_8182247 2.655 ENSMUST00000161898.1
Fgfr1op
Fgfr1 oncogene partner
chr9_-_71896047 2.636 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr14_+_12189943 2.628 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr10_-_37138863 2.612 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr9_+_65630552 2.583 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr19_+_55894508 2.578 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr8_-_112015036 2.576 ENSMUST00000071732.5
Gm6793
predicted gene 6793
chr10_-_13388753 2.487 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr5_-_112228633 2.444 ENSMUST00000182699.1
ENSMUST00000182258.1
ENSMUST00000183036.1
Miat


myocardial infarction associated transcript (non-protein coding)


chr5_-_28210022 2.364 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr1_+_165788681 2.364 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr13_-_113046357 2.350 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr19_+_40831248 2.344 ENSMUST00000025983.6
ENSMUST00000120057.1
Ccnj

cyclin J

chr13_-_29984219 2.339 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr3_+_5218546 2.295 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr14_+_46760526 2.285 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr8_+_88521344 2.261 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr10_-_13388830 2.252 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr9_-_99876147 2.230 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr1_-_183147461 2.228 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr3_+_54481429 2.209 ENSMUST00000091130.3
Gm5641
predicted gene 5641
chr19_+_40831296 2.167 ENSMUST00000119316.1
Ccnj
cyclin J
chr5_-_51553896 2.158 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr2_+_73271925 2.138 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr7_-_37769624 2.076 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr12_+_119945957 2.071 ENSMUST00000058644.8
Tmem196
transmembrane protein 196
chrX_+_71556874 2.071 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr3_+_5218516 2.043 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr2_+_181767283 2.038 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr11_+_78115565 2.037 ENSMUST00000155571.1
Fam222b
family with sequence similarity 222, member B
chr18_+_4921662 2.021 ENSMUST00000143254.1
Svil
supervillin
chr8_+_45507768 2.017 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chrX_+_129749830 1.989 ENSMUST00000113320.2
Diap2
diaphanous homolog 2 (Drosophila)
chr6_+_134035691 1.967 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr2_-_60125651 1.952 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr2_+_181767040 1.945 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chrX_-_38564519 1.936 ENSMUST00000016681.8
Cul4b
cullin 4B
chr12_-_57546121 1.913 ENSMUST00000044380.6
Foxa1
forkhead box A1
chrX_+_129749740 1.888 ENSMUST00000167619.2
ENSMUST00000037854.8
Diap2

diaphanous homolog 2 (Drosophila)

chr12_+_76370266 1.875 ENSMUST00000042779.3
Zbtb1
zinc finger and BTB domain containing 1
chr11_-_49712674 1.867 ENSMUST00000020624.6
ENSMUST00000145353.1
Cnot6

CCR4-NOT transcription complex, subunit 6

chr1_+_165788746 1.819 ENSMUST00000161559.2
Cd247
CD247 antigen
chr4_+_107367757 1.819 ENSMUST00000139560.1
Ndc1
NDC1 transmembrane nucleoporin
chr6_+_29735667 1.809 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr5_-_16731074 1.800 ENSMUST00000073014.5
Gm8991
predicted pseudogene 8991
chr3_-_75956888 1.793 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
Golim4


golgi integral membrane protein 4


chr7_-_73541738 1.792 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chrX_+_143518671 1.784 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr4_+_115057683 1.782 ENSMUST00000161601.1
Tal1
T cell acute lymphocytic leukemia 1
chr2_-_18048347 1.780 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr13_-_98926374 1.773 ENSMUST00000109401.1
Tnpo1
transportin 1
chr12_-_98737405 1.769 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr5_+_108065742 1.752 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr11_-_88718078 1.747 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr19_-_28680077 1.746 ENSMUST00000162022.1
ENSMUST00000112612.2
Glis3

GLIS family zinc finger 3

chr14_-_26442824 1.725 ENSMUST00000136635.1
ENSMUST00000125437.1
Slmap

sarcolemma associated protein

chr3_-_141982224 1.723 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr17_+_53566971 1.721 ENSMUST00000000724.8
Kat2b
K(lysine) acetyltransferase 2B
chr16_+_70314057 1.680 ENSMUST00000171132.1
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr6_+_65042575 1.678 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_+_91257323 1.663 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr10_+_53596936 1.653 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr16_-_56024628 1.646 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr15_-_13173607 1.642 ENSMUST00000036439.4
Cdh6
cadherin 6
chr5_-_21785115 1.633 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr9_+_96259246 1.632 ENSMUST00000179065.1
ENSMUST00000165768.2
Tfdp2

transcription factor Dp 2

chr15_-_50882806 1.626 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr2_-_172370506 1.621 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr2_+_18055203 1.619 ENSMUST00000028076.8
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr14_+_48670147 1.578 ENSMUST00000183522.1
ENSMUST00000184869.1
RP23-131O4.2

RP23-131O4.2

chr7_+_100493795 1.573 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr9_+_54863742 1.560 ENSMUST00000034843.7
Ireb2
iron responsive element binding protein 2
chr2_-_18048784 1.539 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr13_+_14063776 1.538 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
Arid4b




AT rich interactive domain 4B (RBP1-like)




chr16_-_64786321 1.529 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr16_-_4559720 1.527 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr3_+_5218589 1.523 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr9_+_110132015 1.504 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr2_+_31950257 1.478 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr11_-_120598346 1.441 ENSMUST00000026125.2
Alyref
Aly/REF export factor
chrX_+_6415736 1.439 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr8_-_111027752 1.421 ENSMUST00000040241.8
Ddx19b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
chr12_-_56613270 1.392 ENSMUST00000072631.5
Nkx2-9
NK2 homeobox 9
chr11_-_52282564 1.392 ENSMUST00000086844.3
Tcf7
transcription factor 7, T cell specific
chr1_-_181183739 1.389 ENSMUST00000159290.1
Wdr26
WD repeat domain 26
chr19_-_34877880 1.389 ENSMUST00000112460.1
Pank1
pantothenate kinase 1
chr3_+_20057802 1.378 ENSMUST00000002502.5
Hltf
helicase-like transcription factor
chr13_-_75943812 1.376 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3

Rho-related BTB domain containing 3

chr12_-_51829525 1.374 ENSMUST00000179265.1
ENSMUST00000042052.8
Hectd1

HECT domain containing 1

chr14_+_54894573 1.367 ENSMUST00000141446.1
ENSMUST00000139985.1
ENSMUST00000172557.1
Pabpn1


poly(A) binding protein, nuclear 1


chr15_-_84855093 1.355 ENSMUST00000016768.5
Phf21b
PHD finger protein 21B
chr8_-_54529951 1.327 ENSMUST00000067476.8
Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chrX_+_18162575 1.324 ENSMUST00000044484.6
ENSMUST00000052368.8
Kdm6a

lysine (K)-specific demethylase 6A

chr14_+_47663756 1.320 ENSMUST00000022391.7
Ktn1
kinectin 1
chr7_+_100494044 1.318 ENSMUST00000153287.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr5_-_28210168 1.312 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr5_+_108065696 1.297 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr7_+_44896125 1.287 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chr3_-_141931523 1.260 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
3.9 31.0 GO:0048625 myoblast fate commitment(GO:0048625)
3.8 15.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
3.5 13.9 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
2.6 7.8 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
2.1 6.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
2.1 6.2 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
1.8 5.4 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.8 12.5 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
1.7 11.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.5 6.2 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
1.4 4.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.4 2.8 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.3 5.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
1.3 20.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.1 7.5 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
1.0 5.2 GO:0035262 gonad morphogenesis(GO:0035262)
1.0 2.9 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.9 4.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.9 2.8 GO:0038203 TORC2 signaling(GO:0038203)
0.9 1.8 GO:0060242 contact inhibition(GO:0060242)
0.8 2.5 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.8 7.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.8 4.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.8 3.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.8 8.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.7 3.0 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.7 2.2 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.7 1.4 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.7 3.4 GO:0015671 oxygen transport(GO:0015671)
0.6 3.9 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.6 7.1 GO:0060539 diaphragm development(GO:0060539)
0.6 1.9 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.6 7.6 GO:0048853 forebrain morphogenesis(GO:0048853)
0.6 3.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.6 1.9 GO:0002572 pro-T cell differentiation(GO:0002572)
0.6 3.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.6 1.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.5 3.8 GO:0051461 positive regulation of heat generation(GO:0031652) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.5 3.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.5 1.6 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 9.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.5 2.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.5 5.0 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.5 2.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.5 1.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 3.0 GO:0007296 vitellogenesis(GO:0007296)
0.4 3.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 1.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 1.2 GO:0060023 soft palate development(GO:0060023)
0.4 2.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.4 3.2 GO:0048664 neuron fate determination(GO:0048664)
0.4 1.2 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.4 4.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 1.9 GO:2000325 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4 1.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.3 2.8 GO:0010815 bradykinin catabolic process(GO:0010815)
0.3 6.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 5.5 GO:0030903 notochord development(GO:0030903)
0.3 1.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 7.2 GO:0001967 suckling behavior(GO:0001967)
0.3 5.2 GO:0045446 endothelial cell development(GO:0001885) endothelial cell differentiation(GO:0045446)
0.3 6.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.3 9.0 GO:0009409 response to cold(GO:0009409)
0.3 1.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.3 1.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.3 1.6 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.3 2.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 3.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 6.2 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 1.8 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.3 4.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 1.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 0.7 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.2 2.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 1.1 GO:0031133 cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133)
0.2 0.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 2.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.5 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 0.4 GO:0002295 T-helper cell lineage commitment(GO:0002295)
0.2 5.2 GO:0001573 ganglioside metabolic process(GO:0001573)
0.2 1.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 5.2 GO:0090132 epithelial cell migration(GO:0010631) tissue migration(GO:0090130) epithelium migration(GO:0090132)
0.2 7.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 3.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 0.4 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.2 2.1 GO:0003417 growth plate cartilage development(GO:0003417)
0.2 7.0 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.2 2.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 1.9 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 1.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 0.5 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.1 1.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 2.7 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 0.6 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.6 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 1.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 1.2 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 2.0 GO:0060538 skeletal muscle organ development(GO:0060538)
0.1 0.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.5 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1 0.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.4 GO:0090148 membrane fission(GO:0090148)
0.1 0.8 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) detoxification of inorganic compound(GO:0061687)
0.1 2.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 0.8 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.8 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.7 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.3 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.1 3.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.5 GO:0070561 vitamin D receptor signaling pathway(GO:0070561) regulation of hematopoietic stem cell proliferation(GO:1902033)
0.1 0.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.2 GO:0060431 primary lung bud formation(GO:0060431)
0.1 1.1 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 0.8 GO:0043928 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 9.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 1.4 GO:0034453 microtubule anchoring(GO:0034453)
0.1 3.1 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.2 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.1 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382)
0.1 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.7 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1 2.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 2.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.4 GO:0006301 postreplication repair(GO:0006301)
0.1 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 2.6 GO:1901998 toxin transport(GO:1901998)
0.1 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.6 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 2.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.9 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.9 GO:0042552 myelination(GO:0042552)
0.0 0.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.6 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 1.9 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.2 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 1.6 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 1.0 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 1.4 GO:0051028 mRNA transport(GO:0051028)
0.0 1.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 31.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
2.7 5.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.8 9.1 GO:0008623 CHRAC(GO:0008623)
1.4 4.2 GO:0042585 germinal vesicle(GO:0042585)
1.1 3.3 GO:0001674 female germ cell nucleus(GO:0001674)
1.0 4.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.8 3.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.6 1.8 GO:0033193 Lsd1/2 complex(GO:0033193)
0.6 13.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 2.8 GO:0000235 astral microtubule(GO:0000235)
0.4 3.4 GO:0005833 hemoglobin complex(GO:0005833)
0.4 3.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 7.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.3 2.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 30.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 0.9 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.3 1.8 GO:0044294 dendritic growth cone(GO:0044294)
0.3 6.1 GO:0016580 Sin3 complex(GO:0016580)
0.3 3.5 GO:0031105 septin complex(GO:0031105)
0.3 1.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.0 GO:0097165 nuclear stress granule(GO:0097165)
0.2 0.7 GO:0036156 inner dynein arm(GO:0036156)
0.2 2.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 2.8 GO:0031932 TORC2 complex(GO:0031932)
0.2 2.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 70.4 GO:0005667 transcription factor complex(GO:0005667)
0.2 3.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 2.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.9 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 1.4 GO:0016460 myosin II complex(GO:0016460)
0.1 0.7 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 6.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.5 GO:0071564 npBAF complex(GO:0071564)
0.1 2.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 2.2 GO:0043034 costamere(GO:0043034)
0.1 1.7 GO:0035861 site of double-strand break(GO:0035861)
0.1 8.9 GO:0005819 spindle(GO:0005819)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 1.0 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.7 GO:0005844 polysome(GO:0005844)
0.0 2.1 GO:0005643 nuclear pore(GO:0005643)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 99.8 GO:0005634 nucleus(GO:0005634)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.7 GO:0031985 Golgi cisterna(GO:0031985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.8 50.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.6 4.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.9 9.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.8 3.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.7 3.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.7 2.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.6 4.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 2.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.5 3.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.5 1.6 GO:0030350 iron-responsive element binding(GO:0030350)
0.5 4.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.5 10.6 GO:0070410 co-SMAD binding(GO:0070410)
0.5 11.4 GO:0070064 proline-rich region binding(GO:0070064)
0.5 4.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.5 4.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 7.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.4 3.9 GO:0001972 retinoic acid binding(GO:0001972)
0.4 1.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 1.7 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.4 6.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.4 3.4 GO:0048185 activin binding(GO:0048185)
0.4 1.8 GO:0005113 patched binding(GO:0005113)
0.3 3.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 1.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 1.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.3 2.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 1.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.7 GO:0043559 insulin binding(GO:0043559)
0.2 3.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 2.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 3.2 GO:0071837 HMG box domain binding(GO:0071837)
0.2 6.6 GO:0004697 protein kinase C activity(GO:0004697)
0.2 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 10.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 2.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 2.2 GO:0015197 peptide transporter activity(GO:0015197)
0.2 2.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 5.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.6 GO:0035497 cAMP response element binding(GO:0035497)
0.1 3.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 5.4 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 1.4 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 6.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 5.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 2.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 93.4 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.1 1.4 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.1 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.1 GO:0035198 miRNA binding(GO:0035198)
0.1 0.6 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 9.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 20.3 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 5.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 1.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 2.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.8 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 3.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 4.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.9 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 5.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0 10.0 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 6.6 GO:0051015 actin filament binding(GO:0051015)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 1.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0004601 peroxidase activity(GO:0004601)
0.0 1.7 GO:0004386 helicase activity(GO:0004386)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 13.8 GO:0003677 DNA binding(GO:0003677)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 2.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0035496 alpha-1,3-galactosyltransferase activity(GO:0001962) UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)