Motif ID: Maf_Nrl

Z-value: 0.485

Transcription factors associated with Maf_Nrl:

Gene SymbolEntrez IDGene Name
Maf ENSMUSG00000055435.6 Maf
Nrl ENSMUSG00000040632.9 Nrl

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafmm10_v2_chr8_-_115706994_1157070960.144.9e-01Click!


Activity profile for motif Maf_Nrl.

activity profile for motif Maf_Nrl


Sorted Z-values histogram for motif Maf_Nrl

Sorted Z-values for motif Maf_Nrl



Network of associatons between targets according to the STRING database.



First level regulatory network of Maf_Nrl

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 1.435 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr10_+_4710119 1.060 ENSMUST00000105588.1
ENSMUST00000105589.1
 Esr1

estrogen receptor 1 (alpha)

chr7_-_103843154 1.035 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr4_-_135573623 0.643 ENSMUST00000105855.1
 Grhl3
grainyhead-like 3 (Drosophila)
chr1_-_136260873 0.621 ENSMUST00000086395.5
 Gpr25
G protein-coupled receptor 25
chr13_+_72632597 0.594 ENSMUST00000172353.1
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr7_-_110862944 0.588 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr15_-_42676967 0.577 ENSMUST00000022921.5
 Angpt1
angiopoietin 1
chr6_+_110645572 0.571 ENSMUST00000071076.6
ENSMUST00000172951.1
 Grm7

glutamate receptor, metabotropic 7

chr5_+_110544326 0.513 ENSMUST00000040001.7
 Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr15_+_89453913 0.504 ENSMUST00000023291.5
 Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr19_+_55894508 0.455 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr2_+_120476911 0.415 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
 Capn3



calpain 3



chr4_+_155839724 0.400 ENSMUST00000030947.3
 Mxra8
matrix-remodelling associated 8
chr19_+_20601958 0.383 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr5_-_24730635 0.377 ENSMUST00000068693.5
 Wdr86
WD repeat domain 86
chr7_-_70360593 0.364 ENSMUST00000032768.7
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr5_-_115652974 0.364 ENSMUST00000121746.1
ENSMUST00000118576.1
 Ccdc64

coiled-coil domain containing 64

chr6_+_17491216 0.360 ENSMUST00000080469.5
 Met
met proto-oncogene
chr10_+_87859255 0.339 ENSMUST00000105300.2
 Igf1
insulin-like growth factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.5 GO:0015671 oxygen transport(GO:0015671)
0.3 1.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.3 0.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.6 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.6 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.6 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.5 GO:0046958 nonassociative learning(GO:0046958)
0.1 0.5 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.3 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0044299 C-fiber(GO:0044299)
0.1 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.4 1.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 0.6 GO:0070905 serine binding(GO:0070905)
0.0 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)