Motif ID: Mafb

Z-value: 0.895


Transcription factors associated with Mafb:

Gene SymbolEntrez IDGene Name
Mafb ENSMUSG00000074622.3 Mafb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_1603670730.691.1e-04Click!


Activity profile for motif Mafb.

activity profile for motif Mafb


Sorted Z-values histogram for motif Mafb

Sorted Z-values for motif Mafb



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_130936172 5.843 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr13_-_85127514 5.732 ENSMUST00000179230.1
 Gm4076
predicted gene 4076
chr7_-_120202104 5.005 ENSMUST00000033198.5
 Crym
crystallin, mu
chr15_-_81843699 4.703 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chr4_-_136886187 4.298 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr2_+_170731807 3.874 ENSMUST00000029075.4
 Dok5
docking protein 5
chr11_-_116307168 3.721 ENSMUST00000124281.1
 Exoc7
exocyst complex component 7
chr9_-_48911067 3.637 ENSMUST00000003826.7
 Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr18_+_65873478 3.500 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr6_+_127233756 3.002 ENSMUST00000071458.3
 Gm4968
predicted gene 4968
chr9_-_77347816 2.550 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr12_-_24493656 2.480 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr2_-_168741898 2.453 ENSMUST00000109176.1
ENSMUST00000178504.1
 Atp9a

ATPase, class II, type 9A

chr19_-_5510467 2.346 ENSMUST00000070172.4
 Snx32
sorting nexin 32
chr1_-_136260873 2.234 ENSMUST00000086395.5
 Gpr25
G protein-coupled receptor 25
chr9_+_109931774 2.085 ENSMUST00000169851.2
 Map4
microtubule-associated protein 4
chr10_+_40349265 2.078 ENSMUST00000044672.4
ENSMUST00000095743.2
 Cdk19

cyclin-dependent kinase 19

chr7_-_110862944 2.045 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr6_+_124997062 2.005 ENSMUST00000159391.1
 Pianp
PILR alpha associated neural protein
chr19_+_26753588 1.976 ENSMUST00000177116.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 6.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
1.0 5.8 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.0 5.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 4.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.8 4.0 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.4 3.9 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3 3.7 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
1.2 3.6 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.1 3.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 3.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.6 GO:0006334 nucleosome assembly(GO:0006334)
0.1 2.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 2.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.2 2.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 2.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 1.9 GO:0001542 ovulation from ovarian follicle(GO:0001542) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 1.9 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 1.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 1.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 1.9 GO:0007601 visual perception(GO:0007601)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 5.5 GO:0034703 cation channel complex(GO:0034703)
0.1 4.3 GO:0005581 collagen trimer(GO:0005581)
0.0 4.2 GO:0016605 PML body(GO:0016605)
0.1 4.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.0 GO:0072686 mitotic spindle(GO:0072686)
0.3 3.5 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 1.5 GO:0042581 specific granule(GO:0042581)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 1.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 1.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 1.3 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.3 GO:0071564 npBAF complex(GO:0071564)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.3 5.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.6 5.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 3.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.9 3.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.2 3.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.8 GO:0008017 microtubule binding(GO:0008017)
0.1 2.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.4 GO:0005158 insulin receptor binding(GO:0005158)
0.7 2.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.5 2.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.5 1.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 1.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.6 GO:0015459 potassium channel regulator activity(GO:0015459)