Motif ID: Maff

Z-value: 0.504


Transcription factors associated with Maff:

Gene SymbolEntrez IDGene Name
Maff ENSMUSG00000042622.7 Maff

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maffmm10_v2_chr15_+_79347534_793475560.321.1e-01Click!


Activity profile for motif Maff.

activity profile for motif Maff


Sorted Z-values histogram for motif Maff

Sorted Z-values for motif Maff



Network of associatons between targets according to the STRING database.



First level regulatory network of Maff

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_136886187 2.804 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr15_+_3270767 2.639 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr7_-_110862944 2.629 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr13_-_23710714 1.457 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
 Hfe


hemochromatosis


chr13_-_85127514 1.335 ENSMUST00000179230.1
 Gm4076
predicted gene 4076
chr5_+_104435112 1.138 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr17_-_25570678 1.100 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr11_+_82101836 1.063 ENSMUST00000000194.3
 Ccl12
chemokine (C-C motif) ligand 12
chr7_-_100964371 0.935 ENSMUST00000060174.4
 P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr14_+_118787894 0.909 ENSMUST00000047761.6
ENSMUST00000071546.7
 Cldn10

claudin 10

chr6_+_120773633 0.862 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr3_-_59262825 0.857 ENSMUST00000050360.7
 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr16_-_22439719 0.850 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr5_+_140505550 0.769 ENSMUST00000043050.8
ENSMUST00000124142.1
 Chst12

carbohydrate sulfotransferase 12

chr17_-_67950908 0.725 ENSMUST00000164647.1
 Arhgap28
Rho GTPase activating protein 28
chr16_+_72663143 0.722 ENSMUST00000023600.7
 Robo1
roundabout homolog 1 (Drosophila)
chr19_+_26753588 0.716 ENSMUST00000177116.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_136260873 0.700 ENSMUST00000086395.5
 Gpr25
G protein-coupled receptor 25
chr12_+_35047180 0.693 ENSMUST00000048519.9
ENSMUST00000163677.1
 Snx13

sorting nexin 13

chr15_-_33687840 0.663 ENSMUST00000042021.3
 Tspyl5
testis-specific protein, Y-encoded-like 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 2.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 2.6 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.5 1.5 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.4 1.1 GO:0072034 renal vesicle induction(GO:0072034)
0.4 1.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 1.1 GO:0033280 response to vitamin D(GO:0033280)
0.3 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.3 0.9 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.9 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 0.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 0.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 0.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.3 1.5 GO:1990357 terminal web(GO:1990357)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.6 GO:0008430 selenium binding(GO:0008430)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.5 GO:0039706 co-receptor binding(GO:0039706)
0.3 1.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 0.9 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.2 0.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)