Motif ID: Max_Mycn

Z-value: 2.989

Transcription factors associated with Max_Mycn:

Gene SymbolEntrez IDGene Name
Max ENSMUSG00000059436.6 Max
Mycn ENSMUSG00000037169.8 Mycn

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maxmm10_v2_chr12_-_76962178_76962248-0.643.9e-04Click!
Mycnmm10_v2_chr12_-_12941827_12941914-0.135.3e-01Click!


Activity profile for motif Max_Mycn.

activity profile for motif Max_Mycn


Sorted Z-values histogram for motif Max_Mycn

Sorted Z-values for motif Max_Mycn



Network of associatons between targets according to the STRING database.



First level regulatory network of Max_Mycn

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_119578981 11.218 ENSMUST00000117911.1
ENSMUST00000120420.1
 Scn5a

sodium channel, voltage-gated, type V, alpha

chr3_-_95882193 9.118 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
 Gm129


predicted gene 129


chr5_-_76951560 8.802 ENSMUST00000140076.1
 Ppat
phosphoribosyl pyrophosphate amidotransferase
chr11_-_12026732 8.680 ENSMUST00000143915.1
 Grb10
growth factor receptor bound protein 10
chr10_-_77113676 8.489 ENSMUST00000072755.4
ENSMUST00000105409.1
 Col18a1

collagen, type XVIII, alpha 1

chr3_+_104638658 8.424 ENSMUST00000046212.1
 Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr17_-_24960620 8.421 ENSMUST00000024981.7
 Hn1l
hematological and neurological expressed 1-like
chr16_+_32608973 7.952 ENSMUST00000120680.1
 Tfrc
transferrin receptor
chr7_+_144896523 7.874 ENSMUST00000033389.5
 Fgf15
fibroblast growth factor 15
chr11_-_96005872 7.810 ENSMUST00000013559.2
 Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr10_+_127063599 7.525 ENSMUST00000120226.1
ENSMUST00000133115.1
 Cdk4

cyclin-dependent kinase 4

chr5_-_45639501 7.317 ENSMUST00000016023.7
 Fam184b
family with sequence similarity 184, member B
chr11_-_60811228 7.256 ENSMUST00000018744.8
 Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr10_+_127063527 7.107 ENSMUST00000006911.5
 Cdk4
cyclin-dependent kinase 4
chr4_+_137468767 7.090 ENSMUST00000030547.8
ENSMUST00000171332.1
 Hspg2

perlecan (heparan sulfate proteoglycan 2)

chr12_+_17544873 6.999 ENSMUST00000171737.1
 Odc1
ornithine decarboxylase, structural 1
chrX_-_134541847 6.990 ENSMUST00000054213.4
 Timm8a1
translocase of inner mitochondrial membrane 8A1
chr7_-_103843154 6.988 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr5_+_139543889 6.939 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr12_+_117843873 6.780 ENSMUST00000176735.1
ENSMUST00000177339.1
 Cdca7l

cell division cycle associated 7 like


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 686 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 26.9 GO:0051028 mRNA transport(GO:0051028)
0.5 18.8 GO:0006414 translational elongation(GO:0006414)
2.0 18.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
2.6 15.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.7 15.3 GO:0019240 citrulline biosynthetic process(GO:0019240)
1.0 14.7 GO:0010216 maintenance of DNA methylation(GO:0010216)
3.7 14.6 GO:0010288 response to lead ion(GO:0010288)
2.8 14.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.6 12.4 GO:0006220 pyrimidine nucleotide metabolic process(GO:0006220)
0.7 12.1 GO:0038092 nodal signaling pathway(GO:0038092)
1.2 11.7 GO:0046036 CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036)
0.2 11.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.3 11.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
3.7 11.2 GO:0086017 Purkinje myocyte action potential(GO:0086017) membrane depolarization during SA node cell action potential(GO:0086046)
0.7 10.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
2.0 9.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.8 9.9 GO:0033572 transferrin transport(GO:0033572)
1.1 9.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 9.8 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.4 9.5 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 284 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 82.2 GO:0005730 nucleolus(GO:0005730)
0.0 35.7 GO:0005739 mitochondrion(GO:0005739)
0.6 27.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.7 27.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 26.0 GO:0005654 nucleoplasm(GO:0005654)
0.5 25.1 GO:0000791 euchromatin(GO:0000791)
0.1 23.1 GO:0005925 focal adhesion(GO:0005925)
1.2 17.4 GO:0035686 sperm fibrous sheath(GO:0035686)
1.6 15.5 GO:0005642 annulate lamellae(GO:0005642)
0.2 14.6 GO:0022626 cytosolic ribosome(GO:0022626)
0.5 13.8 GO:0015030 Cajal body(GO:0015030)
2.3 13.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 13.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 12.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
1.5 12.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 12.2 GO:0005643 nuclear pore(GO:0005643)
0.2 11.3 GO:0005604 basement membrane(GO:0005604)
1.0 11.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.7 11.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.5 10.8 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 423 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 109.0 GO:0044822 poly(A) RNA binding(GO:0044822)
1.2 34.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.5 23.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.4 19.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.3 18.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.8 17.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 16.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 14.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.5 14.1 GO:0045182 translation regulator activity(GO:0045182)
1.1 13.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.5 12.2 GO:0070064 proline-rich region binding(GO:0070064)
0.7 11.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
3.9 11.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.9 11.6 GO:0031386 protein tag(GO:0031386)
0.1 11.6 GO:0001047 core promoter binding(GO:0001047)
0.2 11.4 GO:0000049 tRNA binding(GO:0000049)
0.8 11.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
1.6 11.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.7 10.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
3.3 9.9 GO:0004998 transferrin receptor activity(GO:0004998)