Motif ID: Maz_Zfp281

Z-value: 1.765

Transcription factors associated with Maz_Zfp281:

Gene SymbolEntrez IDGene Name
Maz ENSMUSG00000030678.6 Maz
Zfp281 ENSMUSG00000041483.8 Zfp281

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp281mm10_v2_chr1_+_136624901_1366249490.554.0e-03Click!
Mazmm10_v2_chr7_-_127026479_127026496-0.029.4e-01Click!


Activity profile for motif Maz_Zfp281.

activity profile for motif Maz_Zfp281


Sorted Z-values histogram for motif Maz_Zfp281

Sorted Z-values for motif Maz_Zfp281



Network of associatons between targets according to the STRING database.



First level regulatory network of Maz_Zfp281

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_144939823 12.808 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr10_-_120476469 11.508 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chrX_-_106485367 9.838 ENSMUST00000140707.1
 Fndc3c1
fibronectin type III domain containing 3C1
chr14_-_98169542 9.779 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chrX_-_106485214 9.474 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr14_-_52316323 8.475 ENSMUST00000135523.1
 Sall2
sal-like 2 (Drosophila)
chr1_-_138847579 7.920 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr16_+_84774123 7.299 ENSMUST00000114195.1
 Jam2
junction adhesion molecule 2
chr3_+_131110350 7.295 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
 Lef1


lymphoid enhancer binding factor 1


chr8_-_87959560 7.081 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr17_+_85620816 6.959 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr13_-_29984219 6.580 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr3_+_87948666 6.395 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr2_+_164562579 6.161 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
 Wfdc2


WAP four-disulfide core domain 2


chr10_+_108332173 6.065 ENSMUST00000095313.3
 Pawr
PRKC, apoptosis, WT1, regulator
chr17_+_85613432 5.962 ENSMUST00000176081.1
 Six3
sine oculis-related homeobox 3
chr7_-_116308241 5.960 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
 Plekha7


pleckstrin homology domain containing, family A member 7


chr7_+_19094594 5.887 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr7_-_144738520 5.812 ENSMUST00000118556.2
ENSMUST00000033393.8
 Ano1

anoctamin 1, calcium activated chloride channel

chr6_-_95718800 5.611 ENSMUST00000079847.5
 Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,181 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 27.6 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.2 21.5 GO:0051028 mRNA transport(GO:0051028)
1.2 18.5 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
1.3 17.1 GO:0032252 secretory granule localization(GO:0032252)
3.4 16.8 GO:0035262 gonad morphogenesis(GO:0035262)
5.3 16.0 GO:0097402 neuroblast migration(GO:0097402)
1.6 16.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 15.4 GO:0008380 RNA splicing(GO:0008380)
1.7 15.2 GO:0010587 miRNA catabolic process(GO:0010587)
1.7 14.9 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.8 13.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.4 13.4 GO:0006270 DNA replication initiation(GO:0006270)
1.5 13.3 GO:0060613 fat pad development(GO:0060613)
0.5 12.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.3 11.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
1.1 11.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 11.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
1.0 11.2 GO:0006105 succinate metabolic process(GO:0006105)
1.9 11.1 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
2.2 11.0 GO:0015705 iodide transport(GO:0015705)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 354 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 144.3 GO:0005634 nucleus(GO:0005634)
0.1 118.8 GO:0005654 nucleoplasm(GO:0005654)
0.2 53.6 GO:0005667 transcription factor complex(GO:0005667)
0.6 37.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.7 31.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 25.3 GO:0005844 polysome(GO:0005844)
0.1 23.2 GO:0005681 spliceosomal complex(GO:0005681)
0.4 22.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 17.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
1.5 16.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 16.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.4 16.4 GO:0005876 spindle microtubule(GO:0005876)
0.1 15.1 GO:0000228 nuclear chromosome(GO:0000228)
0.1 14.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2 13.2 GO:0005643 nuclear pore(GO:0005643)
0.1 13.0 GO:0031965 nuclear membrane(GO:0031965)
0.2 12.6 GO:0005814 centriole(GO:0005814)
0.6 12.0 GO:0016580 Sin3 complex(GO:0016580)
0.6 10.0 GO:0097470 ribbon synapse(GO:0097470)
0.8 9.8 GO:0043219 lateral loop(GO:0043219)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 618 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 99.7 GO:0001159 core promoter proximal region DNA binding(GO:0001159)
0.1 61.2 GO:0003677 DNA binding(GO:0003677)
0.3 27.0 GO:0001047 core promoter binding(GO:0001047)
1.0 24.9 GO:0070064 proline-rich region binding(GO:0070064)
0.3 22.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.4 20.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 19.9 GO:0044822 poly(A) RNA binding(GO:0044822)
1.7 18.6 GO:0003680 AT DNA binding(GO:0003680)
0.2 15.9 GO:0004386 helicase activity(GO:0004386)
0.5 15.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.9 15.3 GO:0070410 co-SMAD binding(GO:0070410)
0.9 15.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.7 15.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.9 14.9 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.6 14.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 14.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 14.2 GO:0051287 NAD binding(GO:0051287)
0.1 14.0 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.9 13.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.7 13.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)