Motif ID: Mbd2
Z-value: 1.524
Transcription factors associated with Mbd2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Mbd2 | ENSMUSG00000024513.10 | Mbd2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mbd2 | mm10_v2_chr18_+_70568189_70568398 | -0.54 | 4.3e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 148 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 19.1 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 0.1 | 11.6 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 1.5 | 9.0 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
| 0.7 | 7.5 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.6 | 6.7 | GO:1901250 | regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
| 1.4 | 5.8 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.2 | 4.8 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 1.6 | 4.7 | GO:0060596 | mammary placode formation(GO:0060596) |
| 1.2 | 4.7 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 0.2 | 4.5 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 1.0 | 4.0 | GO:0021586 | pons maturation(GO:0021586) |
| 0.1 | 4.0 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.1 | 4.0 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.0 | 4.0 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.2 | 3.8 | GO:0055012 | ventricular cardiac muscle cell differentiation(GO:0055012) |
| 0.0 | 3.7 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.0 | 3.6 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
| 0.1 | 3.5 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.1 | 3.5 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.2 | 3.4 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 74 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 16.2 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 8.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.2 | 8.2 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 7.2 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 7.1 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 6.1 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 6.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 5.8 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 0.3 | 5.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 4.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.2 | 4.6 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.8 | 4.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 1.3 | 4.0 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.4 | 3.8 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.2 | 3.4 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.0 | 3.4 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 3.3 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 3.3 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 2.7 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.1 | 2.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 96 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 16.2 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.2 | 10.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.3 | 8.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.4 | 8.1 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.7 | 5.5 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 5.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.4 | 5.1 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.3 | 4.8 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 4.8 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.3 | 4.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 4.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 4.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 4.1 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.2 | 3.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.5 | 3.8 | GO:0030375 | thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.6 | 3.6 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.6 | 3.6 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.1 | 3.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 3.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 3.4 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
