Motif ID: Mecom

Z-value: 0.454


Transcription factors associated with Mecom:

Gene SymbolEntrez IDGene Name
Mecom ENSMUSG00000027684.10 Mecom



Activity profile for motif Mecom.

activity profile for motif Mecom


Sorted Z-values histogram for motif Mecom

Sorted Z-values for motif Mecom



Network of associatons between targets according to the STRING database.



First level regulatory network of Mecom

PNG image of the network

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Top targets:


Showing 1 to 20 of 58 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_897782 6.094 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr1_+_152399824 0.760 ENSMUST00000044311.8
 Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr10_+_3740348 0.682 ENSMUST00000120274.1
 Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr8_+_12385769 0.668 ENSMUST00000080795.8
 Gm5607
predicted gene 5607
chr13_+_104287855 0.642 ENSMUST00000065766.6
 Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr7_-_103853199 0.523 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr2_+_71786923 0.502 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr14_+_115042752 0.500 ENSMUST00000134140.2
 Mir17hg
Mir17 host gene 1 (non-protein coding)
chr3_+_41742615 0.423 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
 D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr1_+_156838915 0.406 ENSMUST00000111720.1
 Angptl1
angiopoietin-like 1
chr6_+_138140298 0.400 ENSMUST00000008684.4
 Mgst1
microsomal glutathione S-transferase 1
chrX_-_113185485 0.339 ENSMUST00000026607.8
ENSMUST00000113388.2
 Chm

choroidermia

chr13_-_103764502 0.302 ENSMUST00000074616.5
 Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr18_+_4994600 0.294 ENSMUST00000140448.1
 Svil
supervillin
chr13_+_89540636 0.277 ENSMUST00000022108.7
 Hapln1
hyaluronan and proteoglycan link protein 1
chr8_-_18741542 0.274 ENSMUST00000033846.6
 Angpt2
angiopoietin 2
chr2_+_103970115 0.255 ENSMUST00000111143.1
ENSMUST00000138815.1
 Lmo2

LIM domain only 2

chr4_+_11704439 0.247 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr1_-_69685937 0.246 ENSMUST00000027146.2
 Ikzf2
IKAROS family zinc finger 2
chr9_+_72806874 0.232 ENSMUST00000055535.8
 Prtg
protogenin homolog (Gallus gallus)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 6.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.7 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.5 GO:0035878 nail development(GO:0035878)
0.1 0.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 6.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425) E-box binding(GO:0070888)
0.1 0.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)