Motif ID: Mef2b
Z-value: 1.278
Transcription factors associated with Mef2b:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Mef2b | ENSMUSG00000079033.3 | Mef2b |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mef2b | mm10_v2_chr8_+_70152754_70152781 | 0.28 | 1.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 11.8 | GO:0015705 | iodide transport(GO:0015705) |
| 2.2 | 6.6 | GO:0042908 | xenobiotic transport(GO:0042908) |
| 2.1 | 8.2 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
| 2.0 | 9.9 | GO:0015671 | oxygen transport(GO:0015671) |
| 2.0 | 5.9 | GO:1990481 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481) |
| 1.4 | 8.4 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.8 | 2.4 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.6 | 3.2 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.6 | 1.9 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 0.6 | 2.4 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.6 | 2.3 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.6 | 2.3 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.5 | 1.5 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
| 0.4 | 1.3 | GO:0060023 | soft palate development(GO:0060023) |
| 0.4 | 1.6 | GO:0019287 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490) |
| 0.4 | 1.8 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.3 | 2.0 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.3 | 1.3 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.3 | 3.2 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.3 | 1.9 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.3 | 0.9 | GO:1903351 | regulation of protein autoubiquitination(GO:1902498) response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
| 0.3 | 0.9 | GO:0003219 | atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219) |
| 0.3 | 1.2 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 0.3 | 0.9 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.3 | 4.2 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
| 0.3 | 0.8 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.2 | 0.7 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.2 | 2.0 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.2 | 1.6 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.2 | 2.0 | GO:1901409 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.2 | 1.6 | GO:0036506 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.2 | 4.1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.2 | 2.6 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.2 | 3.9 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.2 | 1.1 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.2 | 1.7 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.1 | 0.6 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
| 0.1 | 2.2 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.1 | 1.5 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 2.9 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.1 | 0.9 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.1 | 2.6 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
| 0.1 | 1.1 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.1 | 1.0 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 0.1 | 0.7 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.1 | 2.1 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
| 0.1 | 0.5 | GO:2000780 | negative regulation of double-strand break repair(GO:2000780) |
| 0.1 | 0.8 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.1 | 1.1 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 0.9 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 0.3 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 0.1 | 0.4 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.1 | 0.4 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.1 | 0.3 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.1 | 0.4 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.1 | 1.3 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.1 | 3.0 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 1.4 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 0.3 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
| 0.1 | 0.3 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.1 | 0.6 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 2.9 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
| 0.0 | 0.6 | GO:0010388 | cullin deneddylation(GO:0010388) |
| 0.0 | 3.3 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.5 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 2.7 | GO:0002224 | toll-like receptor signaling pathway(GO:0002224) |
| 0.0 | 1.0 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 1.1 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 1.6 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
| 0.0 | 0.9 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 1.0 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
| 0.0 | 1.1 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 0.6 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.0 | 0.9 | GO:0003016 | respiratory system process(GO:0003016) |
| 0.0 | 1.8 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 0.7 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.0 | 0.6 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 0.8 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.0 | 2.2 | GO:0006694 | steroid biosynthetic process(GO:0006694) |
| 0.0 | 1.6 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.0 | 0.5 | GO:0071385 | cellular response to glucocorticoid stimulus(GO:0071385) |
| 0.0 | 4.1 | GO:0042384 | cilium assembly(GO:0042384) |
| 0.0 | 1.1 | GO:0006821 | chloride transport(GO:0006821) |
| 0.0 | 0.5 | GO:0061045 | negative regulation of wound healing(GO:0061045) |
| 0.0 | 0.1 | GO:0031272 | regulation of pseudopodium assembly(GO:0031272) |
| 0.0 | 0.2 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.0 | 2.6 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
| 0.0 | 1.4 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.2 | GO:0046069 | cGMP catabolic process(GO:0046069) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 5.9 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 1.2 | 9.9 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.7 | 7.4 | GO:0001939 | female pronucleus(GO:0001939) |
| 0.5 | 2.4 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.4 | 3.2 | GO:0098536 | deuterosome(GO:0098536) |
| 0.4 | 16.1 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.4 | 1.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.3 | 2.0 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.3 | 8.2 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.3 | 0.9 | GO:0044754 | amphisome(GO:0044753) autolysosome(GO:0044754) |
| 0.3 | 0.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 1.7 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.2 | 0.9 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.2 | 2.3 | GO:0043196 | varicosity(GO:0043196) |
| 0.2 | 2.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 1.5 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 2.1 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 1.3 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 1.6 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 0.3 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.1 | 1.8 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.1 | 2.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 4.1 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 2.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.6 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.0 | 0.7 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 1.1 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.0 | 1.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 2.4 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.7 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 1.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.1 | GO:0090537 | CERF complex(GO:0090537) |
| 0.0 | 2.0 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.8 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 1.0 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 1.8 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 11.8 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 2.5 | 9.9 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
| 2.2 | 8.7 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 1.5 | 5.9 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 1.4 | 8.2 | GO:0035240 | dopamine binding(GO:0035240) |
| 0.7 | 2.2 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.6 | 2.3 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.6 | 1.7 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.5 | 2.6 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.5 | 1.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.5 | 1.8 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.5 | 1.4 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 0.3 | 1.6 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.3 | 1.4 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.3 | 4.1 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.3 | 1.4 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.3 | 0.8 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.3 | 3.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.2 | 4.2 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.2 | 1.9 | GO:0031432 | titin binding(GO:0031432) |
| 0.2 | 1.5 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.2 | 1.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.2 | 1.0 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.2 | 1.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.2 | 2.0 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.2 | 0.5 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 0.1 | 3.0 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 0.4 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.1 | 1.5 | GO:0005536 | glucose binding(GO:0005536) |
| 0.1 | 1.1 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.1 | 0.4 | GO:0008251 | tRNA-specific adenosine deaminase activity(GO:0008251) |
| 0.1 | 1.1 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.1 | 2.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 1.6 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.1 | 2.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.2 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.1 | 0.2 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.1 | 0.9 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
| 0.1 | 3.6 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.1 | 1.5 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.1 | 2.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.6 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.0 | 0.5 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.0 | 2.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.5 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 1.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 1.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.3 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.0 | 0.9 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 2.4 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
| 0.0 | 1.9 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 0.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 6.0 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 2.9 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 0.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.3 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 1.2 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.2 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.0 | 0.6 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.9 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 1.1 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.0 | 0.1 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
| 0.0 | 3.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.6 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.6 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.1 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
