Motif ID: Mef2b

Z-value: 1.278


Transcription factors associated with Mef2b:

Gene SymbolEntrez IDGene Name
Mef2b ENSMUSG00000079033.3 Mef2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mef2bmm10_v2_chr8_+_70152754_701527810.281.6e-01Click!


Activity profile for motif Mef2b.

activity profile for motif Mef2b


Sorted Z-values histogram for motif Mef2b

Sorted Z-values for motif Mef2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Mef2b

PNG image of the network

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Top targets:


Showing 1 to 20 of 190 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103843154 9.888 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr6_-_23248264 8.351 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_142899985 8.216 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr7_-_144738478 7.394 ENSMUST00000121758.1
Ano1
anoctamin 1, calcium activated chloride channel
chr7_-_144738520 4.402 ENSMUST00000118556.2
ENSMUST00000033393.8
Ano1

anoctamin 1, calcium activated chloride channel

chr2_-_94264713 4.390 ENSMUST00000129661.1
E530001K10Rik
RIKEN cDNA E530001K10 gene
chr2_-_94264745 4.235 ENSMUST00000134563.1
E530001K10Rik
RIKEN cDNA E530001K10 gene
chr5_-_116422858 3.657 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr4_+_119108711 3.332 ENSMUST00000030398.3
Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
chr4_+_119108795 3.285 ENSMUST00000134105.1
ENSMUST00000144329.1
Slc2a1

solute carrier family 2 (facilitated glucose transporter), member 1

chr17_-_58991343 3.241 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr2_-_172043466 3.212 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chr3_+_40800013 3.207 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chrX_+_75096039 3.070 ENSMUST00000131155.1
ENSMUST00000132000.1
Dkc1

dyskeratosis congenita 1, dyskerin

chr1_+_187609028 2.997 ENSMUST00000110939.1
Esrrg
estrogen-related receptor gamma
chr18_+_50030977 2.927 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr6_-_126939524 2.868 ENSMUST00000144954.1
ENSMUST00000112221.1
ENSMUST00000112220.1
Rad51ap1


RAD51 associated protein 1


chrX_+_75095854 2.856 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chrX_+_159303266 2.657 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr3_+_138143429 2.638 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 11.8 GO:0015705 iodide transport(GO:0015705)
2.0 9.9 GO:0015671 oxygen transport(GO:0015671)
1.4 8.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.1 8.2 GO:0042414 epinephrine metabolic process(GO:0042414)
2.2 6.6 GO:0042908 xenobiotic transport(GO:0042908)
2.0 5.9 GO:1990481 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
0.3 4.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 4.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 4.1 GO:0042384 cilium assembly(GO:0042384)
0.2 3.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 3.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.6 3.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.3 3.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 3.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 2.9 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 2.7 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.2 2.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 2.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 2.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 16.1 GO:0034707 chloride channel complex(GO:0034707)
1.2 9.9 GO:0005833 hemoglobin complex(GO:0005833)
0.3 8.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.7 7.4 GO:0001939 female pronucleus(GO:0001939)
1.5 5.9 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 4.1 GO:0005814 centriole(GO:0005814)
0.4 3.2 GO:0098536 deuterosome(GO:0098536)
0.0 2.6 GO:0030118 clathrin coat(GO:0030118)
0.5 2.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 2.4 GO:0000922 spindle pole(GO:0000922)
0.2 2.3 GO:0043196 varicosity(GO:0043196)
0.1 2.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 2.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.1 GO:0031528 microvillus membrane(GO:0031528)
0.3 2.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 2.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.0 GO:0016607 nuclear speck(GO:0016607)
0.4 1.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.8 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 11.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
2.5 9.9 GO:0031721 hemoglobin alpha binding(GO:0031721)
2.2 8.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
1.4 8.2 GO:0035240 dopamine binding(GO:0035240)
0.0 6.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.5 5.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 4.2 GO:0070402 NADPH binding(GO:0070402)
0.3 4.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 3.6 GO:0000049 tRNA binding(GO:0000049)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.3 3.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 3.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.5 2.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 2.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.6 2.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.7 2.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 2.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)