Motif ID: Meis2

Z-value: 1.301


Transcription factors associated with Meis2:

Gene SymbolEntrez IDGene Name
Meis2 ENSMUSG00000027210.14 Meis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis2mm10_v2_chr2_-_116065798_1160658530.423.3e-02Click!


Activity profile for motif Meis2.

activity profile for motif Meis2


Sorted Z-values histogram for motif Meis2

Sorted Z-values for motif Meis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_49822710 7.440 ENSMUST00000031843.6
 Npy
neuropeptide Y
chr4_+_105790534 5.675 ENSMUST00000185012.1
 Gm12728
predicted gene 12728
chr7_+_44850393 5.186 ENSMUST00000136232.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr1_+_194619815 5.054 ENSMUST00000027952.5
 Plxna2
plexin A2
chr5_-_109558957 5.008 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2
chr4_+_105789869 4.770 ENSMUST00000184254.1
 Gm12728
predicted gene 12728
chr8_-_89187560 4.747 ENSMUST00000093326.2
 Gm5356
predicted pseudogene 5356
chr9_-_121495678 4.546 ENSMUST00000035120.4
 Cck
cholecystokinin
chr5_-_100159261 4.140 ENSMUST00000139520.1
 Tmem150c
transmembrane protein 150C
chr3_-_82074639 4.036 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr4_+_128058962 3.866 ENSMUST00000184063.1
 Csmd2
CUB and Sushi multiple domains 2
chr12_-_24493656 3.698 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr8_+_120114144 3.665 ENSMUST00000108948.1
ENSMUST00000034281.6
ENSMUST00000108951.1
 6430548M08Rik


RIKEN cDNA 6430548M08 gene


chr7_+_48959089 3.526 ENSMUST00000183659.1
 Nav2
neuron navigator 2
chr19_+_42247544 3.483 ENSMUST00000122375.1
 Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr10_+_93589413 3.449 ENSMUST00000181835.1
 4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr2_+_158667119 3.395 ENSMUST00000045503.4
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr1_-_6215292 3.133 ENSMUST00000097832.1
 4732440D04Rik
RIKEN cDNA 4732440D04 gene
chr3_-_107518001 3.047 ENSMUST00000169449.1
ENSMUST00000029499.8
 Slc6a17

solute carrier family 6 (neurotransmitter transporter), member 17

chr18_+_36939178 3.032 ENSMUST00000115662.2
 Pcdha2
protocadherin alpha 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 7.4 GO:0019732 antifungal humoral response(GO:0019732)
1.5 6.2 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 5.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.5 5.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.3 5.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.5 5.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.2 5.1 GO:0007020 microtubule nucleation(GO:0007020)
0.8 5.0 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
1.5 4.6 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 4.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 4.0 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 4.0 GO:0008643 carbohydrate transport(GO:0008643)
0.1 3.7 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.9 3.5 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 3.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 3.0 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 3.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 3.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 2.9 GO:0000209 protein polyubiquitination(GO:0000209)
0.9 2.6 GO:1904457 positive regulation of neuronal action potential(GO:1904457)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.2 GO:0043195 terminal bouton(GO:0043195)
0.1 8.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.5 5.2 GO:0031931 TORC1 complex(GO:0031931)
0.5 5.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.9 4.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 4.5 GO:0043203 axon hillock(GO:0043203)
0.9 4.4 GO:0044316 cone cell pedicle(GO:0044316)
0.5 4.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 4.3 GO:0000139 Golgi membrane(GO:0000139)
0.2 4.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 3.5 GO:0008021 synaptic vesicle(GO:0008021)
0.2 2.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.9 GO:0097060 synaptic membrane(GO:0097060)
0.2 2.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.6 GO:0043198 dendritic shaft(GO:0043198)
0.6 2.5 GO:0045098 type III intermediate filament(GO:0045098)
0.2 2.4 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.1 2.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.4 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 11.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 7.2 GO:0003779 actin binding(GO:0003779)
0.4 6.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 5.4 GO:0005125 cytokine activity(GO:0005125)
0.4 5.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.9 4.6 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.5 4.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 4.0 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 3.4 GO:0030552 cAMP binding(GO:0030552)
0.0 3.4 GO:0008201 heparin binding(GO:0008201)
0.5 3.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 3.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 3.0 GO:0030553 cGMP binding(GO:0030553)
0.3 2.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 2.8 GO:0017124 SH3 domain binding(GO:0017124)
0.2 2.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.6 2.5 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 2.5 GO:0019215 intermediate filament binding(GO:0019215)
0.1 2.4 GO:0005179 hormone activity(GO:0005179)