Motif ID: Meox2

Z-value: 0.591


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_371085460.357.5e-02Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

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Top targets:


Showing 1 to 20 of 161 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_26119811 2.073 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26259109 2.004 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr16_-_26989974 1.884 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr13_+_104229366 1.852 ENSMUST00000022227.6
 Cenpk
centromere protein K
chr9_-_36726374 1.712 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1


chr14_+_25980039 1.621 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr8_-_46294592 1.487 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr12_+_117843489 1.297 ENSMUST00000021592.9
 Cdca7l
cell division cycle associated 7 like
chr16_+_14906622 1.262 ENSMUST00000090277.1
 Efcab1
EF hand calcium binding domain 1
chr6_+_5390387 1.157 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr14_+_25979401 1.048 ENSMUST00000173580.1
 Duxbl1
double homeobox B-like 1
chr12_-_54986363 1.009 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr8_-_4779513 0.947 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr14_-_20496780 0.859 ENSMUST00000022353.3
 Mss51
MSS51 mitochondrial translational activator
chr14_+_26119173 0.816 ENSMUST00000174564.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 0.816 ENSMUST00000172517.1
 Duxbl3
double homeobox B-like 3
chr15_-_99651580 0.789 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
 Racgap1




Rac GTPase-activating protein 1




chr3_+_107291215 0.773 ENSMUST00000029502.7
 Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr3_+_127553462 0.760 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr3_-_98339921 0.740 ENSMUST00000065793.5
 Phgdh
3-phosphoglycerate dehydrogenase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 1.9 GO:0006270 DNA replication initiation(GO:0006270)
0.3 1.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.5 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.1 1.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 1.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.2 0.9 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.9 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 0.8 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 0.7 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.7 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.7 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.7 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.2 0.6 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 0.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.6 GO:1901970 positive regulation of mitotic sister chromatid separation(GO:1901970)
0.1 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0000776 kinetochore(GO:0000776)
0.0 1.7 GO:0005657 replication fork(GO:0005657)
0.3 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.0 GO:0008623 CHRAC(GO:0008623)
0.0 1.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.2 0.8 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0070469 respiratory chain(GO:0070469)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.6 GO:0032797 SMN complex(GO:0032797)
0.0 0.6 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 1.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 1.1 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.0 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.7 GO:0051287 NAD binding(GO:0051287)
0.2 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)