Motif ID: Msx3

Z-value: 0.364


Transcription factors associated with Msx3:

Gene SymbolEntrez IDGene Name
Msx3 ENSMUSG00000025469.9 Msx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Msx3mm10_v2_chr7_-_140049140_1400491800.048.5e-01Click!


Activity profile for motif Msx3.

activity profile for motif Msx3


Sorted Z-values histogram for motif Msx3

Sorted Z-values for motif Msx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Msx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 63 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_53975246 1.115 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chr4_-_14621805 0.969 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr2_-_45117349 0.856 ENSMUST00000176438.2
 Zeb2
zinc finger E-box binding homeobox 2
chr4_-_14621494 0.715 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr1_-_158356258 0.664 ENSMUST00000004133.8
 Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr10_+_81257277 0.570 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
 Matk


megakaryocyte-associated tyrosine kinase


chr13_+_83732438 0.518 ENSMUST00000182701.1
 C130071C03Rik
RIKEN cDNA C130071C03 gene
chrX_-_143933204 0.467 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr10_+_39612934 0.448 ENSMUST00000019987.6
 Traf3ip2
TRAF3 interacting protein 2
chr4_+_102254739 0.447 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chrX_-_143933089 0.424 ENSMUST00000087313.3
 Dcx
doublecortin
chr2_-_33087169 0.400 ENSMUST00000102810.3
 Garnl3
GTPase activating RANGAP domain-like 3
chr2_-_33086366 0.400 ENSMUST00000049618.2
 Garnl3
GTPase activating RANGAP domain-like 3
chr7_+_103550368 0.392 ENSMUST00000106888.1
 Olfr613
olfactory receptor 613
chr5_+_14514918 0.385 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr18_+_37819543 0.376 ENSMUST00000055935.5
 Pcdhga9
protocadherin gamma subfamily A, 9
chr17_+_21383725 0.320 ENSMUST00000056107.4
ENSMUST00000162659.1
 Zfp677

zinc finger protein 677

chr4_-_14621669 0.319 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr9_+_35423582 0.284 ENSMUST00000154652.1
 Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr7_-_127895578 0.280 ENSMUST00000033074.6
 Vkorc1
vitamin K epoxide reductase complex, subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.0 GO:0019532 oxalate transport(GO:0019532)
0.0 1.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.9 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0043015 cAMP binding(GO:0030552) gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.1 0.2 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)