Motif ID: Mtf1

Z-value: 0.800


Transcription factors associated with Mtf1:

Gene SymbolEntrez IDGene Name
Mtf1 ENSMUSG00000028890.7 Mtf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mtf1mm10_v2_chr4_+_124802543_1248026780.067.6e-01Click!


Activity profile for motif Mtf1.

activity profile for motif Mtf1


Sorted Z-values histogram for motif Mtf1

Sorted Z-values for motif Mtf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mtf1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_94172618 9.562 ENSMUST00000034214.6
Mt2
metallothionein 2
chr8_+_94179089 5.587 ENSMUST00000034215.6
Mt1
metallothionein 1
chr11_-_32222233 3.019 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr11_+_63133068 2.791 ENSMUST00000108700.1
Pmp22
peripheral myelin protein 22
chr11_+_63132569 2.738 ENSMUST00000108701.1
Pmp22
peripheral myelin protein 22
chr1_+_135729147 1.379 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr6_-_39118211 1.349 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr14_-_26170283 1.181 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr9_-_56635624 1.069 ENSMUST00000114256.1
Lingo1
leucine rich repeat and Ig domain containing 1
chr4_+_134496996 1.031 ENSMUST00000095074.3
Paqr7
progestin and adipoQ receptor family member VII
chr5_+_105415738 0.944 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr9_+_57940104 0.784 ENSMUST00000043059.7
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr1_+_131867224 0.711 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr12_-_4592927 0.672 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr4_+_129985098 0.661 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2

brain-specific angiogenesis inhibitor 2

chr8_-_70776650 0.613 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr3_-_94412883 0.607 ENSMUST00000181305.1
1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr11_+_94741782 0.596 ENSMUST00000021240.6
Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr15_-_58214882 0.576 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr4_+_129984833 0.573 ENSMUST00000120204.1
Bai2
brain-specific angiogenesis inhibitor 2
chr2_+_91237110 0.543 ENSMUST00000181191.1
A330069E16Rik
RIKEN cDNA A330069E16 gene
chr1_+_191906743 0.534 ENSMUST00000044954.6
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr2_+_150323702 0.532 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr10_+_70245083 0.532 ENSMUST00000046807.6
Slc16a9
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr17_-_56716788 0.526 ENSMUST00000067931.5
Vmac
vimentin-type intermediate filament associated coiled-coil protein
chr13_-_45964964 0.526 ENSMUST00000180110.1
ENSMUST00000091628.3
ENSMUST00000167708.2
Atxn1


ataxin 1


chr16_-_91597636 0.509 ENSMUST00000023686.8
Tmem50b
transmembrane protein 50B
chr8_+_13159135 0.430 ENSMUST00000033824.6
Lamp1
lysosomal-associated membrane protein 1
chr18_+_14424821 0.421 ENSMUST00000069552.5
Gm5160
predicted gene 5160
chr3_-_121815212 0.411 ENSMUST00000029770.5
Abcd3
ATP-binding cassette, sub-family D (ALD), member 3
chr1_-_166002591 0.407 ENSMUST00000111429.4
ENSMUST00000176800.1
Pou2f1

POU domain, class 2, transcription factor 1

chr13_-_23934156 0.404 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr1_-_166002613 0.390 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1



POU domain, class 2, transcription factor 1



chr7_+_5056856 0.364 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr7_+_132610620 0.353 ENSMUST00000033241.5
Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr5_-_125341043 0.328 ENSMUST00000111390.1
ENSMUST00000086075.6
Scarb1

scavenger receptor class B, member 1

chr17_+_47688992 0.327 ENSMUST00000156118.1
Frs3
fibroblast growth factor receptor substrate 3
chr8_+_123373778 0.316 ENSMUST00000057934.3
ENSMUST00000108840.2
Tcf25

transcription factor 25 (basic helix-loop-helix)

chr2_-_91236877 0.313 ENSMUST00000111352.1
Ddb2
damage specific DNA binding protein 2
chr2_-_91236967 0.303 ENSMUST00000028696.4
Ddb2
damage specific DNA binding protein 2
chr3_+_107895916 0.296 ENSMUST00000172247.1
ENSMUST00000167387.1
Gstm5

glutathione S-transferase, mu 5

chr4_+_103619580 0.291 ENSMUST00000106827.1
Dab1
disabled 1
chr9_-_14381242 0.282 ENSMUST00000167549.1
Endod1
endonuclease domain containing 1
chr12_+_24572276 0.271 ENSMUST00000085553.5
Grhl1
grainyhead-like 1 (Drosophila)
chr7_-_43313233 0.257 ENSMUST00000012796.7
ENSMUST00000107986.2
Zfp715

zinc finger protein 715

chr10_-_81001338 0.255 ENSMUST00000099462.1
ENSMUST00000118233.1
Gng7

guanine nucleotide binding protein (G protein), gamma 7

chr19_-_4839286 0.244 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr3_-_58692391 0.241 ENSMUST00000070368.7
Siah2
seven in absentia 2
chr18_+_11839220 0.233 ENSMUST00000171109.1
ENSMUST00000046948.8
Cables1

CDK5 and Abl enzyme substrate 1

chr5_+_57718021 0.225 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr17_+_71673255 0.219 ENSMUST00000097284.3
Fam179a
family with sequence similarity 179, member A
chr9_-_112187898 0.218 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr7_-_141539784 0.209 ENSMUST00000118694.1
ENSMUST00000153191.1
ENSMUST00000166082.1
ENSMUST00000026586.6
Chid1



chitinase domain containing 1



chr2_-_130664565 0.207 ENSMUST00000089559.4
Ddrgk1
DDRGK domain containing 1
chr13_+_23934434 0.199 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr1_+_179668202 0.198 ENSMUST00000040538.3
Sccpdh
saccharopine dehydrogenase (putative)
chr7_-_43313063 0.169 ENSMUST00000135130.1
ENSMUST00000139061.1
Zfp715

zinc finger protein 715

chr6_+_90619241 0.164 ENSMUST00000032177.8
Slc41a3
solute carrier family 41, member 3
chr7_+_119794102 0.163 ENSMUST00000084644.2
2610020H08Rik
RIKEN cDNA 2610020H08 gene
chr10_+_17723220 0.127 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr8_-_54529951 0.126 ENSMUST00000067476.8
Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr1_-_64122256 0.121 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr3_+_107896247 0.119 ENSMUST00000169365.1
Gstm5
glutathione S-transferase, mu 5
chr1_-_167393826 0.115 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr3_+_107895821 0.114 ENSMUST00000004134.4
Gstm5
glutathione S-transferase, mu 5
chr5_+_115506668 0.100 ENSMUST00000067268.8
ENSMUST00000086523.3
Pxn

paxillin

chr12_+_33957645 0.094 ENSMUST00000049089.5
Twist1
twist basic helix-loop-helix transcription factor 1
chr7_+_119793987 0.089 ENSMUST00000033218.8
ENSMUST00000106520.1
2610020H08Rik

RIKEN cDNA 2610020H08 gene

chr2_-_173119402 0.089 ENSMUST00000094287.3
ENSMUST00000179693.1
Ctcfl

CCCTC-binding factor (zinc finger protein)-like

chr10_+_77606217 0.084 ENSMUST00000129492.1
ENSMUST00000141228.2
Sumo3

SMT3 suppressor of mif two 3 homolog 3 (yeast)

chr10_+_77606571 0.080 ENSMUST00000099538.5
Sumo3
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr11_+_50131342 0.074 ENSMUST00000093138.6
ENSMUST00000101270.4
Tbc1d9b

TBC1 domain family, member 9B

chr4_-_93335510 0.070 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr17_-_83631892 0.068 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr8_+_84872105 0.062 ENSMUST00000136026.1
ENSMUST00000170296.1
Syce2

synaptonemal complex central element protein 2

chr10_-_39899238 0.053 ENSMUST00000178563.1
AA474331
expressed sequence AA474331
chr10_+_20952547 0.051 ENSMUST00000105525.4
Ahi1
Abelson helper integration site 1
chr8_+_70905970 0.049 ENSMUST00000019405.2
Map1s
microtubule-associated protein 1S
chr15_-_83149307 0.036 ENSMUST00000100375.4
Poldip3
polymerase (DNA-directed), delta interacting protein 3
chr18_-_84589491 0.036 ENSMUST00000125763.1
Zfp407
zinc finger protein 407
chr9_+_78175898 0.025 ENSMUST00000180974.1
C920006O11Rik
RIKEN cDNA C920006O11 gene
chr6_-_56923927 0.009 ENSMUST00000031793.5
Nt5c3
5'-nucleotidase, cytosolic III

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 15.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.5 0.5 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.3 5.5 GO:0032060 bleb assembly(GO:0032060)
0.2 0.6 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.3 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.6 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.5 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 3.0 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.3 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.4 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0030862 regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 1.0 GO:0048477 oogenesis(GO:0048477)
0.0 0.2 GO:0019430 removal of superoxide radicals(GO:0019430)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 GO:0043218 compact myelin(GO:0043218)
0.1 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 5.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.0 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 5.8 GO:0005507 copper ion binding(GO:0005507)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.2 GO:0004568 chitinase activity(GO:0004568)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0005496 steroid binding(GO:0005496)