Motif ID: Mtf1

Z-value: 0.800


Transcription factors associated with Mtf1:

Gene SymbolEntrez IDGene Name
Mtf1 ENSMUSG00000028890.7 Mtf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mtf1mm10_v2_chr4_+_124802543_1248026780.067.6e-01Click!


Activity profile for motif Mtf1.

activity profile for motif Mtf1


Sorted Z-values histogram for motif Mtf1

Sorted Z-values for motif Mtf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mtf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 82 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_94172618 9.562 ENSMUST00000034214.6
 Mt2
metallothionein 2
chr8_+_94179089 5.587 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr11_-_32222233 3.019 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr11_+_63133068 2.791 ENSMUST00000108700.1
 Pmp22
peripheral myelin protein 22
chr11_+_63132569 2.738 ENSMUST00000108701.1
 Pmp22
peripheral myelin protein 22
chr1_+_135729147 1.379 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr6_-_39118211 1.349 ENSMUST00000038398.6
 Parp12
poly (ADP-ribose) polymerase family, member 12
chr14_-_26170283 1.181 ENSMUST00000100809.4
 Plac9b
placenta specific 9b
chr9_-_56635624 1.069 ENSMUST00000114256.1
 Lingo1
leucine rich repeat and Ig domain containing 1
chr4_+_134496996 1.031 ENSMUST00000095074.3
 Paqr7
progestin and adipoQ receptor family member VII
chr5_+_105415738 0.944 ENSMUST00000112707.1
 Lrrc8b
leucine rich repeat containing 8 family, member B
chr9_+_57940104 0.784 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr1_+_131867224 0.711 ENSMUST00000112386.1
ENSMUST00000027693.7
 Rab7l1

RAB7, member RAS oncogene family-like 1

chr12_-_4592927 0.672 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr4_+_129985098 0.661 ENSMUST00000106017.1
ENSMUST00000121049.1
 Bai2

brain-specific angiogenesis inhibitor 2

chr8_-_70776650 0.613 ENSMUST00000034296.8
 Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr3_-_94412883 0.607 ENSMUST00000181305.1
 1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr11_+_94741782 0.596 ENSMUST00000021240.6
 Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr15_-_58214882 0.576 ENSMUST00000022986.6
 Fbxo32
F-box protein 32
chr4_+_129984833 0.573 ENSMUST00000120204.1
 Bai2
brain-specific angiogenesis inhibitor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 15.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.3 5.5 GO:0032060 bleb assembly(GO:0032060)
0.0 3.0 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 1.4 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 1.0 GO:0048477 oogenesis(GO:0048477)
0.1 0.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 0.6 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.6 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.5 0.5 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.5 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.3 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.5 GO:0043218 compact myelin(GO:0043218)
0.0 5.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.0 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0000801 central element(GO:0000801)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 GO:0005507 copper ion binding(GO:0005507)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:0005496 steroid binding(GO:0005496)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)