Motif ID: Myb

Z-value: 2.475


Transcription factors associated with Myb:

Gene SymbolEntrez IDGene Name
Myb ENSMUSG00000019982.8 Myb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybmm10_v2_chr10_-_21160925_211609840.922.3e-11Click!


Activity profile for motif Myb.

activity profile for motif Myb


Sorted Z-values histogram for motif Myb

Sorted Z-values for motif Myb



Network of associatons between targets according to the STRING database.



First level regulatory network of Myb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_123749696 9.631 ENSMUST00000031366.7
 Kntc1
kinetochore associated 1
chr18_+_60925612 9.000 ENSMUST00000102888.3
ENSMUST00000025519.4
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr2_-_127831817 8.325 ENSMUST00000028858.7
 Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr16_+_64851991 7.664 ENSMUST00000067744.7
 Cggbp1
CGG triplet repeat binding protein 1
chr16_-_46496955 7.652 ENSMUST00000023335.6
ENSMUST00000023334.8
 Pvrl3

poliovirus receptor-related 3

chr1_-_191575534 7.639 ENSMUST00000027933.5
 Dtl
denticleless homolog (Drosophila)
chrX_+_58030999 7.529 ENSMUST00000088631.4
ENSMUST00000088629.3
 Zic3

zinc finger protein of the cerebellum 3

chr9_+_72438534 7.354 ENSMUST00000034746.8
 Mns1
meiosis-specific nuclear structural protein 1
chr11_+_23665615 7.346 ENSMUST00000109525.1
ENSMUST00000020520.4
 Pus10

pseudouridylate synthase 10

chr17_-_70851189 7.243 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr9_+_72438519 7.227 ENSMUST00000184604.1
 Mns1
meiosis-specific nuclear structural protein 1
chr11_+_23666007 7.035 ENSMUST00000058163.4
 Pus10
pseudouridylate synthase 10
chr2_+_118813995 6.730 ENSMUST00000134661.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding
chr7_-_144939823 6.711 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr6_-_28261907 6.613 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
 Zfp800



zinc finger protein 800



chr2_+_118814195 6.602 ENSMUST00000110842.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding
chr2_+_118814237 6.457 ENSMUST00000028803.7
ENSMUST00000126045.1
 Knstrn

kinetochore-localized astrin/SPAG5 binding

chr10_+_84838143 6.283 ENSMUST00000095388.4
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chrX_-_102157065 6.067 ENSMUST00000056904.2
 Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr2_-_37703275 5.830 ENSMUST00000072186.5
 Strbp
spermatid perinuclear RNA binding protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 23.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 17.8 GO:0007067 mitotic nuclear division(GO:0007067)
2.1 16.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.0 14.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.9 14.6 GO:0070986 left/right axis specification(GO:0070986)
0.7 14.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.4 14.0 GO:0007099 centriole replication(GO:0007099)
2.1 12.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.8 12.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 11.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 10.8 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
1.8 10.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 10.3 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.6 10.0 GO:0022027 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
1.8 8.8 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.5 8.3 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.7 8.2 GO:0019985 translesion synthesis(GO:0019985)
0.5 7.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.0 7.8 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
1.0 7.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 29.9 GO:0005813 centrosome(GO:0005813)
0.2 26.8 GO:0000776 kinetochore(GO:0000776)
0.6 19.8 GO:0035371 microtubule plus-end(GO:0035371)
0.7 19.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 15.9 GO:0005730 nucleolus(GO:0005730)
0.2 14.8 GO:0005882 intermediate filament(GO:0005882)
0.0 13.8 GO:0005635 nuclear envelope(GO:0005635)
0.2 11.5 GO:0005814 centriole(GO:0005814)
1.1 11.0 GO:0005642 annulate lamellae(GO:0005642)
0.3 10.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 10.1 GO:0005871 kinesin complex(GO:0005871)
0.5 9.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
3.2 9.6 GO:1990423 RZZ complex(GO:1990423)
0.1 8.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 8.4 GO:0005643 nuclear pore(GO:0005643)
2.1 8.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.4 8.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.5 7.8 GO:0031616 spindle pole centrosome(GO:0031616)
1.1 7.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 6.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.2 14.4 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.5 12.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 11.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.8 10.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 10.1 GO:0003777 microtubule motor activity(GO:0003777)
0.3 8.7 GO:0017025 TBP-class protein binding(GO:0017025)
2.7 8.0 GO:0097100 supercoiled DNA binding(GO:0097100)
2.0 7.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 7.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 7.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.4 7.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 7.2 GO:0070410 co-SMAD binding(GO:0070410)
0.3 6.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 6.7 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 6.4 GO:0042393 histone binding(GO:0042393)
0.9 6.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 6.0 GO:0004386 helicase activity(GO:0004386)
0.0 6.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.5 5.9 GO:1990226 histone methyltransferase binding(GO:1990226)