Motif ID: Mybl1

Z-value: 1.108


Transcription factors associated with Mybl1:

Gene SymbolEntrez IDGene Name
Mybl1 ENSMUSG00000025912.10 Mybl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl1mm10_v2_chr1_-_9700209_97003290.433.0e-02Click!


Activity profile for motif Mybl1.

activity profile for motif Mybl1


Sorted Z-values histogram for motif Mybl1

Sorted Z-values for motif Mybl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mybl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_126862431 3.764 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chrX_-_106485214 3.518 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr17_+_29093763 3.334 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr19_+_60144682 3.086 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr9_+_78191966 3.072 ENSMUST00000034903.5
Gsta4
glutathione S-transferase, alpha 4
chr11_+_32276400 3.061 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr2_+_118814195 2.802 ENSMUST00000110842.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr2_+_118813995 2.777 ENSMUST00000134661.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr2_+_118814237 2.721 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr7_+_79660196 2.632 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chrX_-_102157065 2.631 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chrX_+_50841434 2.610 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr9_+_7764041 2.530 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr14_-_48662740 2.529 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_121506715 2.432 ENSMUST00000028676.5
Wdr76
WD repeat domain 76
chr11_-_69921190 2.369 ENSMUST00000108607.1
Eif5a
eukaryotic translation initiation factor 5A
chr17_-_26095487 2.335 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr14_-_20181773 2.283 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr17_-_23844155 2.267 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
Prss41


protease, serine, 41


chr4_+_65124174 2.266 ENSMUST00000084501.3
Pappa
pregnancy-associated plasma protein A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 238 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.4 GO:0007067 mitotic nuclear division(GO:0007067)
0.5 8.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 6.3 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.2 6.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.9 5.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5 4.7 GO:0090399 replicative senescence(GO:0090399)
1.0 4.0 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.1 3.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 3.2 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.8 3.1 GO:0003360 brainstem development(GO:0003360)
0.6 3.1 GO:0015671 oxygen transport(GO:0015671)
0.1 3.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 2.8 GO:0051384 response to glucocorticoid(GO:0051384)
0.1 2.7 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.5 2.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.8 2.5 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.6 2.5 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 2.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 2.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.8 2.4 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 132 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.1 GO:0005730 nucleolus(GO:0005730)
0.3 9.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 8.3 GO:0005643 nuclear pore(GO:0005643)
0.6 5.8 GO:0005642 annulate lamellae(GO:0005642)
0.0 5.7 GO:0005681 spliceosomal complex(GO:0005681)
0.2 4.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 3.8 GO:0000776 kinetochore(GO:0000776)
0.1 3.5 GO:0005776 autophagosome(GO:0005776)
0.0 3.4 GO:0005635 nuclear envelope(GO:0005635)
1.1 3.3 GO:0070557 PCNA-p21 complex(GO:0070557)
1.0 3.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 3.1 GO:0035861 site of double-strand break(GO:0035861)
0.1 3.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 2.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.7 2.2 GO:1990423 RZZ complex(GO:1990423)
0.1 2.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.7 2.0 GO:0033186 CAF-1 complex(GO:0033186)
0.3 1.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 1.8 GO:0071004 U2-type prespliceosome(GO:0071004)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 162 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.7 GO:0044822 poly(A) RNA binding(GO:0044822)
0.0 8.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 6.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 5.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 4.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.5 4.0 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 3.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 3.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 3.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.6 3.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.5 3.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 3.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 3.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.5 2.5 GO:0042610 CD8 receptor binding(GO:0042610)
0.5 2.4 GO:0032027 myosin light chain binding(GO:0032027)
0.0 2.4 GO:0003684 damaged DNA binding(GO:0003684)
0.2 2.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 2.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.3 GO:0042393 histone binding(GO:0042393)
0.1 2.2 GO:0070034 telomerase RNA binding(GO:0070034)