Motif ID: Neurod1

Z-value: 1.087


Transcription factors associated with Neurod1:

Gene SymbolEntrez IDGene Name
Neurod1 ENSMUSG00000034701.9 Neurod1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurod1mm10_v2_chr2_-_79456750_794567610.862.6e-08Click!


Activity profile for motif Neurod1.

activity profile for motif Neurod1


Sorted Z-values histogram for motif Neurod1

Sorted Z-values for motif Neurod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 8.067 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr11_-_98329641 6.316 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr6_-_136171722 6.135 ENSMUST00000053880.6
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_-_25319095 4.684 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
 Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr3_+_18054258 4.538 ENSMUST00000026120.6
 Bhlhe22
basic helix-loop-helix family, member e22
chr12_+_29528382 4.246 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr5_-_142608785 4.235 ENSMUST00000037048.7
 Mmd2
monocyte to macrophage differentiation-associated 2
chr18_+_45268876 4.202 ENSMUST00000183850.1
ENSMUST00000066890.7
 Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr2_-_29253001 3.875 ENSMUST00000071201.4
 Ntng2
netrin G2
chr6_+_54681687 3.722 ENSMUST00000046276.6
 2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr2_+_90885860 3.570 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr15_-_99705490 3.544 ENSMUST00000163472.2
 Gm17349
predicted gene, 17349
chr16_+_42907563 3.030 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr10_+_69706326 3.028 ENSMUST00000182992.1
 Ank3
ankyrin 3, epithelial
chr11_+_32000452 3.023 ENSMUST00000020537.2
ENSMUST00000109409.1
 Nsg2

neuron specific gene family member 2

chr13_+_54949388 2.908 ENSMUST00000026994.7
ENSMUST00000109994.2
 Unc5a

unc-5 homolog A (C. elegans)

chr16_-_67620880 2.885 ENSMUST00000114292.1
ENSMUST00000120898.1
 Cadm2

cell adhesion molecule 2

chr10_-_110000219 2.867 ENSMUST00000032719.7
 Nav3
neuron navigator 3
chr11_-_120041774 2.650 ENSMUST00000103019.1
 Aatk
apoptosis-associated tyrosine kinase
chr11_-_107915041 2.625 ENSMUST00000039071.2
 Cacng5
calcium channel, voltage-dependent, gamma subunit 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 8.5 GO:0021542 dentate gyrus development(GO:0021542)
2.1 6.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 6.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 6.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.9 5.7 GO:1900673 olefin metabolic process(GO:1900673)
0.2 5.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.8 4.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 4.2 GO:0019835 cytolysis(GO:0019835)
0.1 4.2 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 3.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 3.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 3.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 2.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 2.9 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.2 2.7 GO:2000821 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.9 2.6 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 2.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 2.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 2.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.5 2.4 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 6.1 GO:0043083 synaptic cleft(GO:0043083)
0.2 6.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 5.8 GO:0045211 postsynaptic membrane(GO:0045211)
1.4 5.7 GO:0044307 dendritic branch(GO:0044307)
0.3 5.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 4.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 4.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 3.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 3.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.8 GO:0005901 caveola(GO:0005901)
0.1 2.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.1 2.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.8 2.4 GO:0043512 inhibin A complex(GO:0043512)
0.2 2.4 GO:0031045 dense core granule(GO:0031045)
0.1 2.4 GO:0060170 ciliary membrane(GO:0060170)
0.1 2.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.1 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 11.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 7.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.2 5.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.9 5.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 5.5 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 5.5 GO:0004672 protein kinase activity(GO:0004672)
0.1 5.1 GO:0070888 E-box binding(GO:0070888)
1.1 4.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 3.9 GO:0042393 histone binding(GO:0042393)
0.3 3.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 3.1 GO:0005125 cytokine activity(GO:0005125)
0.0 3.0 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.5 2.9 GO:0005042 netrin receptor activity(GO:0005042)
0.3 2.7 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 2.6 GO:0003680 AT DNA binding(GO:0003680)
0.2 2.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 2.6 GO:0017022 myosin binding(GO:0017022)
0.8 2.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 2.4 GO:0070699 type II activin receptor binding(GO:0070699)