Motif ID: Neurog2

Z-value: 0.394


Transcription factors associated with Neurog2:

Gene SymbolEntrez IDGene Name
Neurog2 ENSMUSG00000027967.7 Neurog2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurog2mm10_v2_chr3_+_127633134_127633140-0.116.1e-01Click!


Activity profile for motif Neurog2.

activity profile for motif Neurog2


Sorted Z-values histogram for motif Neurog2

Sorted Z-values for motif Neurog2



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurog2

PNG image of the network

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Top targets:


Showing 1 to 20 of 181 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_105790534 0.584 ENSMUST00000185012.1
 Gm12728
predicted gene 12728
chr11_+_73160403 0.445 ENSMUST00000006104.3
 P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr7_-_126704816 0.424 ENSMUST00000032949.7
 Coro1a
coronin, actin binding protein 1A
chr10_+_110920170 0.423 ENSMUST00000020403.5
 Csrp2
cysteine and glycine-rich protein 2
chr11_-_69920892 0.414 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
 Eif5a


eukaryotic translation initiation factor 5A


chr13_-_97747373 0.368 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_-_126704736 0.346 ENSMUST00000131415.1
 Coro1a
coronin, actin binding protein 1A
chr9_-_21918089 0.326 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
 Rab3d



RAB3D, member RAS oncogene family



chr16_-_31314804 0.323 ENSMUST00000115230.1
ENSMUST00000130560.1
 Apod

apolipoprotein D

chr3_-_120886691 0.320 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
 6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr7_-_126704522 0.309 ENSMUST00000135087.1
 Coro1a
coronin, actin binding protein 1A
chr11_+_100320596 0.307 ENSMUST00000152521.1
 Eif1
eukaryotic translation initiation factor 1
chrX_+_7579666 0.304 ENSMUST00000115740.1
ENSMUST00000115739.1
 Foxp3

forkhead box P3

chr11_-_102365111 0.301 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr13_+_49544443 0.301 ENSMUST00000177948.1
ENSMUST00000021820.6
 Aspn

asporin

chr11_-_69920581 0.290 ENSMUST00000108610.1
 Eif5a
eukaryotic translation initiation factor 5A
chr9_+_108560422 0.280 ENSMUST00000081111.8
 Impdh2
inosine 5'-phosphate dehydrogenase 2
chr15_-_77970750 0.270 ENSMUST00000100484.4
 Eif3d
eukaryotic translation initiation factor 3, subunit D
chr14_+_74732297 0.268 ENSMUST00000022573.10
ENSMUST00000175712.1
 Esd

esterase D/formylglutathione hydrolase

chr3_+_118430299 0.267 ENSMUST00000180774.1
 Gm26871
predicted gene, 26871

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.1 GO:0032796 uropod organization(GO:0032796)
0.1 0.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.4 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.1 0.3 GO:0032829 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) negative regulation of interleukin-2 biosynthetic process(GO:0045085) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0002159 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
0.1 0.2 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 0.5 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.1 GO:0034916 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)