Motif ID: Nfatc4

Z-value: 0.583


Transcription factors associated with Nfatc4:

Gene SymbolEntrez IDGene Name
Nfatc4 ENSMUSG00000023411.5 Nfatc4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc4mm10_v2_chr14_+_55824795_55824889-0.291.5e-01Click!


Activity profile for motif Nfatc4.

activity profile for motif Nfatc4


Sorted Z-values histogram for motif Nfatc4

Sorted Z-values for motif Nfatc4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_56978534 4.488 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr4_+_48049080 3.410 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr13_+_83504032 3.151 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr19_+_26623419 2.852 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_56969864 2.811 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr15_+_92051153 1.920 ENSMUST00000169825.1
Cntn1
contactin 1
chr15_+_3270767 1.523 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr11_+_97415527 1.304 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr1_-_170110491 1.283 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr19_-_4943049 1.221 ENSMUST00000133254.1
ENSMUST00000120475.1
ENSMUST00000025834.7
Peli3


pellino 3


chr2_+_55435918 1.215 ENSMUST00000067101.3
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
chr13_+_31806627 1.179 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr16_+_43364145 1.178 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr14_+_70555900 1.114 ENSMUST00000163060.1
Hr
hairless
chr12_-_84450944 0.874 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr6_-_59024340 0.764 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr5_+_117363513 0.743 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr6_-_59024470 0.720 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr13_-_52981027 0.685 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr9_+_113812547 0.654 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr2_-_66410064 0.576 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr1_-_126830632 0.554 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr4_+_130107556 0.531 ENSMUST00000030563.5
Pef1
penta-EF hand domain containing 1
chr11_+_29692937 0.505 ENSMUST00000102843.3
ENSMUST00000102842.3
ENSMUST00000078830.4
ENSMUST00000170731.1
Rtn4



reticulon 4



chr12_+_76533540 0.500 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrX_+_7638674 0.497 ENSMUST00000128890.1
Syp
synaptophysin
chr3_-_37125943 0.490 ENSMUST00000029275.5
Il2
interleukin 2
chr1_+_34005872 0.479 ENSMUST00000182296.1
Dst
dystonin
chr14_-_25927250 0.457 ENSMUST00000100811.5
Tmem254a
transmembrane protein 254a
chr10_+_21993890 0.449 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr1_-_193370260 0.426 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr1_-_193370225 0.419 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr14_-_25927672 0.419 ENSMUST00000185006.1
Tmem254a
transmembrane protein 254a
chr6_+_134981998 0.392 ENSMUST00000167323.1
Apold1
apolipoprotein L domain containing 1
chr12_-_86079019 0.392 ENSMUST00000003687.6
Tgfb3
transforming growth factor, beta 3
chr11_-_35980473 0.388 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr14_-_26067355 0.375 ENSMUST00000100819.5
Tmem254c
transmembrane protein 254c
chr11_-_47379405 0.359 ENSMUST00000077221.5
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr2_+_125136692 0.308 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr2_+_116067213 0.307 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chrX_+_48623737 0.292 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_-_73660351 0.255 ENSMUST00000154258.1
Chn1
chimerin (chimaerin) 1
chr12_+_91400990 0.251 ENSMUST00000021346.7
ENSMUST00000021343.6
Tshr

thyroid stimulating hormone receptor

chr17_-_49564262 0.249 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr15_-_79932516 0.232 ENSMUST00000177044.1
ENSMUST00000109615.1
ENSMUST00000089293.4
ENSMUST00000109616.2
Cbx7



chromobox 7



chr15_-_79062866 0.211 ENSMUST00000151889.1
ENSMUST00000040676.4
Ankrd54

ankyrin repeat domain 54

chr19_+_8839298 0.201 ENSMUST00000160556.1
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr2_-_116067391 0.201 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr5_+_145114280 0.184 ENSMUST00000141602.1
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr19_-_8839181 0.159 ENSMUST00000096259.4
Gng3
guanine nucleotide binding protein (G protein), gamma 3
chr12_+_84451485 0.154 ENSMUST00000137170.1
Lin52
lin-52 homolog (C. elegans)
chr1_-_126830786 0.116 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr19_-_24477356 0.103 ENSMUST00000099556.1
Fam122a
family with sequence similarity 122, member A
chr1_-_64121456 0.099 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr1_-_64121389 0.086 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr3_-_106001474 0.082 ENSMUST00000066319.6
Pifo
primary cilia formation
chr19_+_29101375 0.077 ENSMUST00000064393.5
Rcl1
RNA terminal phosphate cyclase-like 1
chr3_+_94837533 0.077 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr8_-_64205970 0.071 ENSMUST00000066166.4
Tll1
tolloid-like
chr7_-_79920599 0.059 ENSMUST00000075657.6
Ap3s2
adaptor-related protein complex 3, sigma 2 subunit
chr11_+_75468040 0.041 ENSMUST00000043598.7
ENSMUST00000108435.1
Tlcd2

TLC domain containing 2

chr8_-_41041828 0.035 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr3_-_96594128 0.026 ENSMUST00000145001.1
ENSMUST00000091924.3
Polr3gl

polymerase (RNA) III (DNA directed) polypeptide G like


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.1 3.2 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.5 7.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 1.2 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.4 1.2 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.3 2.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 0.9 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.3 1.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 1.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.4 GO:1905005 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 1.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.9 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 2.9 GO:0071564 npBAF complex(GO:0071564)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 8.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 3.2 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.5 GO:0030315 T-tubule(GO:0030315)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 GO:0003680 AT DNA binding(GO:0003680)
0.2 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 3.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.2 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.5 GO:0008430 selenium binding(GO:0008430)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 2.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.9 GO:0001948 glycoprotein binding(GO:0001948)
0.0 1.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)